Aberrant DNA methylation of p57KIP2 identifies a cell-cycle regulatory pathway with prognostic impact in adult acute lymphocytic leukemia. - Wikidata - awgldk - TriplyDB

Aberrant DNA methylation of p57KIP2 identifies a cell-cycle regulatory pathway with prognostic impact in adult acute lymphocytic leukemia.

Aberrant DNA methylation of p57KIP2 identifies a cell-cycle regulatory pathway with prognostic impact in adult acute lymphocytic leukemia.

http://www.wikidata.org/entity/Q33186068

about

Tumor Suppressor Inactivation in the Pathogenesis of Adult T-Cell Leukemia Imprinted CDKN1C is a tumor suppressor in rhabdoid tumor and activated by restoration of SMARCB1 and histone deacetylase inhibitors DNA methylation predicts survival and response to therapy in patients with myelodysplastic syndromes Safety and clinical activity of 5-aza-2'-deoxycytidine (decitabine) with or without Hyper-CVAD in relapsed/refractory acute lymphocytic leukaemia.Imprinting disruption of the CDKN1C/KCNQ1OT1 domain: the molecular mechanisms causing Beckwith-Wiedemann syndrome and cancer.Evolution of decitabine development: accomplishments, ongoing investigations, and future strategies Estrogen-mediated epigenetic repression of the imprinted gene cyclin-dependent kinase inhibitor 1C in breast cancer cells.p53 Family: Role of Protein Isoforms in Human Cancer.DNA methylation in haematological malignancies: the role of decitabine.Characterization, tissue expression, and imprinting analysis of the porcine CDKN1C and NAP1L4 genes.Phase 1/2 study of the combination of 5-aza-2'-deoxycytidine with valproic acid in patients with leukemia.Genome-wide DNA methylation profiling of chronic lymphocytic leukemia allows identification of epigenetically repressed molecular pathways with clinical impact.Molecular marks for epigenetic identification of developmental and cancer stem cells Transcriptional upregulation of p57 (Kip2) by the cyclin-dependent kinase inhibitor BMS-387032 is E2F dependent and serves as a negative feedback loop limiting cytotoxicity Correlation between CpG methylation profiles and hormone receptor status in breast cancers.Adverse prognostic impact of CDKN2B hyper-methylation in acute promyelocytic leukemia.Mutation of epigenetic regulators TET2 and MLL3 in patients with HTLV-I-induced acute adult T-cell leukemia.Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray Aberrant CpG island methylation in acute myeloid leukemia is accentuated at relapse.Poor prognosis in acute lymphoblastic leukemia may relate to promoter hypermethylation of cancer-related genes.Residual DNA methylation at remission is prognostic in adult Philadelphia chromosome-negative acute lymphocytic leukemia.Downregulation of JUNB mRNA expression in advanced phase chronic myelogenous leukemia.Epigenetics of acute lymphocytic leukemia.Transforming growth factor beta-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation.Impact of aberrant DNA methylation patterns including CYP1B1 methylation in adolescents and young adults with acute lymphocytic leukemia.Age-related epigenetic drift in the pathogenesis of MDS and AML.Role of epigenetic therapy in myelodysplastic syndrome.Targeting epigenetics through histone deacetylase inhibitors in acute lymphoblastic leukemia.Cell cycle regulatory molecular profiles of pediatric T-cell lymphoblastic leukemia and lymphoma.Role of p53 family members p73 and p63 in human hematological malignancies.Rapamycin restores p14, p15 and p57 expression and inhibits the mTOR/p70S6K pathway in acute lymphoblastic leukemia cells.DNA methylation of membrane-bound tyrosine phosphatase genes in acute lymphoblastic leukaemia.Aberrant methylation and decreased expression of the RIZ1 gene are frequent in adult acute lymphoblastic leukemia of T-cell phenotype.Differential tumor suppressor properties and transforming growth factor-beta responsiveness of p57KIP2 in leukemia cells with aberrant p57KIP2 promoter DNA methylation.Aberrant DNA methylation associated with silencing BNIP3 gene expression in haematopoietic tumours.Alternative mechanisms associated with silencing of CDKN1C in Beckwith-Wiedemann syndrome.Some facts and thoughts: p73 as a tumor suppressor gene in the network of tumor suppressors.Aberrant EPHB4 gene methylation and childhood acute lymphoblastic leukemia.RNA-Seq reveals the existence of a CDKN1C-E2F1-TP53 axis that is altered in human T-cell lymphoblastic lymphomas.Genetic and Epigenetic Control of CDKN1C Expression: Importance in Cell Commitment and Differentiation, Tissue Homeostasis and Human Diseases.

P2860

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P2860

Aberrant DNA methylation of p57KIP2 identifies a cell-cycle regulatory pathway with prognostic impact in adult acute lymphocytic leukemia.

http://www.wikidata.org/entity/Q33186068

description

2003 nî lūn-bûn

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2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2003 թվականի փետրվարին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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Aberrant DNA methylation of p5 ...... lt acute lymphocytic leukemia.

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Aberrant DNA methylation of p5 ...... lt acute lymphocytic leukemia.

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type

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Aberrant DNA methylation of p5 ...... lt acute lymphocytic leukemia.

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Aberrant DNA methylation of p5 ...... lt acute lymphocytic leukemia.

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Aberrant DNA methylation of p5 ...... lt acute lymphocytic leukemia.

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Aberrant DNA methylation of p5 ...... lt acute lymphocytic leukemia.

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Aberrant DNA methylation of p5 ...... lt acute lymphocytic leukemia.

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Jean-Pierre J Issa

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Kohzoh Imai

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LanLan Shen

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Minoru Toyota

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Sophia Daniel

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Toshiro Obata

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Yutaka Kondo

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4131-4136

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scholarly article

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10.1182/BLOOD-2002-08-2466

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10

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Hagop Kantarjian

Guillermo Garcia-Manero

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2003-02-13T00:00:00Z

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10899739

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DNA methylation