Addressing polyspecificity of antibodies selected from an in vitro yeast presentation system: a FACS-based, high-throughput selection and analytical tool.
about
Serology in the 21st century: the molecular-level analysis of the serum antibody repertoireImproving monoclonal antibody selection and engineering using measurements of colloidal protein interactionsFive birds, one stone: neutralization of α-hemolysin and 4 bi-component leukocidins of Staphylococcus aureus with a single human monoclonal antibody.Discovery of high affinity anti-ricin antibodies by B cell receptor sequencing and by yeast display of combinatorial VH:VL libraries from immunized animals.Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin of Staphylococcus aureus for the generation of neutralizing antibodies.Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design.High throughput cross-interaction measures for human IgG1 antibodies correlate with clearance rates in miceIsolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreakBroad epitope coverage of a human in vitro antibody library.Rapid profiling of RSV antibody repertoires from the memory B cells of naturally infected adult donorsBiophysical properties of the clinical-stage antibody landscape.An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability.High-throughput screening for developability during early-stage antibody discovery using self-interaction nanoparticle spectroscopy.Pharmacokinetic de-risking tools for selection of monoclonal antibody lead candidates.Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo.Target-independent variable region mediated effects on antibody clearance can be FcRn independent.Facile Affinity Maturation of Antibody Variable Domains Using Natural Diversity Mutagenesis.An alternative assay to hydrophobic interaction chromatography for high-throughput characterization of monoclonal antibodies.Chaperone proteins as single component reagents to assess antibody nonspecificity.Nonspecificity in a nonimmune human scFv repertoire.Antibody engineering and therapeutics, The Annual Meeting of the Antibody Society: December 8-12, 2013, Huntington Beach, CAPrinciples for computational design of binding antibodies.Reduction of Nonspecificity Motifs in Synthetic Antibody Libraries.Arginine mutations in antibody complementarity-determining regions display context-dependent affinity/specificity trade-offs.A role for macromolecular crowding in off-target binding of therapeutic antibodies.Productive common light chain libraries yield diverse panels of high affinity bispecific antibodies.Purification of common light chain IgG-like bispecific antibodies using highly linear pH gradients.Discovery of highly soluble antibodies prior to purification using affinity-capture self-interaction nanoparticle spectroscopy.Single-Domain Antibodies and the Promise of Modular Targeting in Cancer Imaging and Treatment.Assessing the function of pneumococcal neuraminidases NanA, NanB and NanC in in vitro and in vivo lung infection models using monoclonal antibodies
P2860
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P2860
Addressing polyspecificity of antibodies selected from an in vitro yeast presentation system: a FACS-based, high-throughput selection and analytical tool.
description
2013 nî lūn-bûn
@nan
2013 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Addressing polyspecificity of ...... selection and analytical tool.
@ast
Addressing polyspecificity of ...... selection and analytical tool.
@en
Addressing polyspecificity of ...... selection and analytical tool.
@nl
type
label
Addressing polyspecificity of ...... selection and analytical tool.
@ast
Addressing polyspecificity of ...... selection and analytical tool.
@en
Addressing polyspecificity of ...... selection and analytical tool.
@nl
prefLabel
Addressing polyspecificity of ...... selection and analytical tool.
@ast
Addressing polyspecificity of ...... selection and analytical tool.
@en
Addressing polyspecificity of ...... selection and analytical tool.
@nl
P2093
P2860
P356
P1476
Addressing polyspecificity of ...... selection and analytical tool.
@en
P2093
Bianka Prinz
Eric Krauland
Jerry Thomas
Joshua Torrey
K Dane Wittrup
Maximiliano Vásquez
Piotr Bobrowicz
Tingwan Sun
William Roach
P2860
P304
P356
10.1093/PROTEIN/GZT047
P50
P577
2013-09-17T00:00:00Z