GPCR deorphanizations: the novel, the known and the unexpected transmitters.
about
IUPHAR-DB: the IUPHAR database of G protein-coupled receptors and ion channelsThe orphan GPR50 receptor specifically inhibits MT1 melatonin receptor function through heterodimerizationCharacterization of an orphan G protein-coupled receptor, GPR20, that constitutively activates Gi proteinsDo orphan G-protein-coupled receptors have ligand-independent functions? New insights from receptor heterodimersProduction of bioactive peptides in an in vitro systemThe effects of propionate and valerate on insulin responsiveness for glucose uptake in 3T3-L1 adipocytes and C2C12 myotubes via G protein-coupled receptor 41Engineering vascularized tissues using natural and synthetic small moleculesGPR3 receptor, a novel actor in the emotional-like responsesIdentifying structural features on 1,1-diphenyl-hexahydro-oxazolo[3,4-a]pyrazin-3-ones critical for Neuropeptide S antagonist activityStructure-activity studies on neuropeptide S: identification of the amino acid residues crucial for receptor activation.Identification of farnesyl pyrophosphate and N-arachidonylglycine as endogenous ligands for GPR92Differential Virtual Screening (DVS) with Active and Inactive Molecular Models for Finding and Profiling GPCR Modulators: Case of the CCK1 Receptor.A Strategy Combining Differential Low-Throughput Screening and Virtual Screening (DLS-VS) Accelerating the Discovery of new Modulators for the Orphan GPR34 Receptor.Probing cell type-specific functions of Gi in vivo identifies GPCR regulators of insulin secretion.Investigating endogenous peptides and peptidases using peptidomicsAPJ acts as a dual receptor in cardiac hypertrophy.Impact of GPCRs in clinical medicine: monogenic diseases, genetic variants and drug targetsGenetic variation in G-protein-coupled receptors--consequences for G-protein-coupled receptors as drug targets.Modulating and evaluating receptor promiscuity through directed evolution and modeling.GLIDA: GPCR--ligand database for chemical genomics drug discovery--database and tools updateMechanism of N-terminal modulation of activity at the melanocortin-4 receptor GPCR.A constitutively active GPCR governs morphogenic transitions in Cryptococcus neoformansTopology of class A G protein-coupled receptors: insights gained from crystal structures of rhodopsins, adrenergic and adenosine receptorsPharmacological characterization of a selective agonist for bombesin receptor subtype-3.Deorphanization of novel peptides and their receptors.Novel neuropeptides as ligands of orphan G protein-coupled receptors.Low affinity GPCRs for metabolic intermediates: challenges for pharmacologists.Activation of GPR40 as a therapeutic target for the treatment of type 2 diabetes.Possible abilities of dietary factors to prevent and treat diabetes via the stimulation of glucagon-like peptide-1 secretion.Discovery and validation of novel peptide agonists for G-protein-coupled receptors.Regulation of prostaglandin EP1 and EP4 receptor signaling by carrier-mediated ligand reuptake.G-protein-coupled receptors: evolving views on physiological signalling: symposium on G-protein-coupled receptors: evolving concepts and new techniques.RHYTHM--a server to predict the orientation of transmembrane helices in channels and membrane-coils.Role of GPR120 in cell motile activity induced by 12-O-tetradecanoylphorbol-13-acetate in liver epithelial WB-F344 cells.
P2860
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P2860
GPCR deorphanizations: the novel, the known and the unexpected transmitters.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
GPCR deorphanizations: the novel, the known and the unexpected transmitters.
@ast
GPCR deorphanizations: the novel, the known and the unexpected transmitters.
@en
type
label
GPCR deorphanizations: the novel, the known and the unexpected transmitters.
@ast
GPCR deorphanizations: the novel, the known and the unexpected transmitters.
@en
prefLabel
GPCR deorphanizations: the novel, the known and the unexpected transmitters.
@ast
GPCR deorphanizations: the novel, the known and the unexpected transmitters.
@en
P1476
GPCR deorphanizations: the novel, the known and the unexpected transmitters.
@en
P2093
Olivier Civelli
P356
10.1016/J.TIPS.2004.11.005
P577
2005-01-01T00:00:00Z