ERK-mediated phosphorylation of Thr735 in TNFalpha-converting enzyme and its potential role in TACE protein trafficking.
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Transforming growth factor beta engages TACE and ErbB3 to activate phosphatidylinositol-3 kinase/Akt in ErbB2-overexpressing breast cancer and desensitizes cells to trastuzumabA Disintegrin and Metalloprotease 17 in the Cardiovascular and Central Nervous SystemsRegulation and function of TPL-2, an IκB kinase-regulated MAP kinase kinase kinaseA biosensor for the activity of the "sheddase" TACE (ADAM17) reveals novel and cell type-specific mechanisms of TACE activationCentral role of the exchange factor GEF-H1 in TNF-α-induced sequential activation of Rac, ADAM17/TACE, and RhoA in tubular epithelial cells.GSK3 and Polo-like kinase regulate ADAM13 function during cranial neural crest cell migration.PKCα and PKCδ regulate ADAM17-mediated ectodomain shedding of heparin binding-EGF through separate pathways.Ectodomain Shedding by ADAM17: Its Role in Neutrophil Recruitment and the Impairment of This Process during SepsisPhosphorylation of iRhom2 at the plasma membrane controls mammalian TACE-dependent inflammatory and growth factor signalling.ADAM-17: the enzyme that does it all.Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte traffickingTACE/ADAM-17 phosphorylation by PKC-epsilon mediates premalignant changes in tobacco smoke-exposed lung cellsRAS mutations affect tumor necrosis factor-induced apoptosis in colon carcinoma cells via ERK-modulatory negative and positive feedback circuits along with non-ERK pathway effectsALCAM/CD166 is a TGF-β-responsive marker and functional regulator of prostate cancer metastasis to boneHuman beta1-adrenergic receptor is subject to constitutive and regulated N-terminal cleavageInvestigation of the role of TNF-α converting enzyme (TACE) in the inhibition of cell surface and soluble TNF-α production by acute ethanol exposureSuppression of ADAM17-mediated Lyn/Akt pathways induces apoptosis of human leukemia U937 cells: Bungarus multicinctus protease inhibitor-like protein-1 uncovers the cytotoxic mechanismTumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACENetwork dynamics determine the autocrine and paracrine signaling functions of TNF.A1 adenosine receptor-stimulated exocytosis in bladder umbrella cells requires phosphorylation of ADAM17 Ser-811 and EGF receptor transactivation.Direct activation of TACE-mediated ectodomain shedding by p38 MAP kinase regulates EGF receptor-dependent cell proliferation.TACE activation by MAPK-mediated regulation of cell surface dimerization and TIMP3 association.A mechanism of male germ cell apoptosis induced by bisphenol-A and nonylphenol involving ADAM17 and p38 MAPK activation.Migration of growth factor-stimulated epithelial and endothelial cells depends on EGFR transactivation by ADAM17.Transiently reduced PI3K/Akt activity drives the development of regulatory function in antigen-stimulated Naïve T-cells.Differential surface expression of ADAM10 and ADAM17 on human T lymphocytes and tumor cells.TNF-α converting enzyme-mediated ErbB4 transactivation by TNF promotes colonic epithelial cell survivalNeurotrophins regulate ApoER2 proteolysis through activation of the Trk signaling pathway.The extracellular regulated kinase-1 (ERK1) controls regulated alpha-secretase-mediated processing, promoter transactivation, and mRNA levels of the cellular prion protein.Shedding of the Mer tyrosine kinase receptor is mediated by ADAM17 protein through a pathway involving reactive oxygen species, protein kinase Cδ, and p38 mitogen-activated protein kinase (MAPK).Substrate selectivity of epidermal growth factor-receptor ligand sheddases and their regulation by phorbol esters and calcium influx.Inhibitory role of TACE/ADAM17 cytotail in protein ectodomain sheddingHigh-throughput protease activity cytometry reveals dose-dependent heterogeneity in PMA-mediated ADAM17 activation.Different signaling pathways stimulate a disintegrin and metalloprotease-17 (ADAM17) in neutrophils during apoptosis and activation.Structure of the EGF receptor transactivation circuit integrates multiple signals with cell context.Regulation of a disintegrin and metalloprotease-33 expression by transforming growth factor-β.p38γ and p38δ kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activationα-Lipoic acid reduces neurogenic hypertension by blunting oxidative stress-mediated increase in ADAM17.A systematic study of modulation of ADAM-mediated ectodomain shedding by site-specific O-glycosylation.A role for cGMP in inducible nitric-oxide synthase (iNOS)-induced tumor necrosis factor (TNF) α-converting enzyme (TACE/ADAM17) activation, translocation, and TNF receptor 1 (TNFR1) shedding in hepatocytes.
P2860
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P2860
ERK-mediated phosphorylation of Thr735 in TNFalpha-converting enzyme and its potential role in TACE protein trafficking.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
ERK-mediated phosphorylation o ...... e in TACE protein trafficking.
@ast
ERK-mediated phosphorylation o ...... e in TACE protein trafficking.
@en
type
label
ERK-mediated phosphorylation o ...... e in TACE protein trafficking.
@ast
ERK-mediated phosphorylation o ...... e in TACE protein trafficking.
@en
prefLabel
ERK-mediated phosphorylation o ...... e in TACE protein trafficking.
@ast
ERK-mediated phosphorylation o ...... e in TACE protein trafficking.
@en
P2093
P356
P1476
ERK-mediated phosphorylation o ...... e in TACE protein trafficking.
@en
P2093
Bethany Everson
David W H Riches
Gillian Murphy
Surinder M Soond
P304
P356
10.1242/JCS.02357
P407
P577
2005-06-01T00:00:00Z