Pathogenic T-cell clones in autoimmune diabetes: more lessons from the NOD mouse.
about
Chromogranin A is an autoantigen in type 1 diabetesDendritic cells in islets of Langerhans constitutively present beta cell-derived peptides bound to their class II MHC moleculesRapid identification of MHC class I-restricted antigens relevant to autoimmune diabetes using retrogenic T cells.IL-21 limits peripheral lymphocyte numbers through T cell homeostatic mechanismsInsulin as a key autoantigen in the development of type 1 diabetesZnT8-reactive T cells are weakly pathogenic in NOD mice but can participate in diabetes under inflammatory conditionsAn update on the use of NOD mice to study autoimmune (Type 1) diabetes.Unique autoreactive T cells recognize insulin peptides generated within the islets of Langerhans in autoimmune diabetes.Loss of T cell CD98 H chain specifically ablates T cell clonal expansion and protects from autoimmunityIslet amyloid polypeptide is a target antigen for diabetogenic CD4+ T cells.Prevention of type 1 diabetes in the rat with an allele-specific anti-T-cell receptor antibody: Vβ13 as a therapeutic target and biomarkerModulation of redox balance leaves murine diabetogenic TH1 T cells "LAG-3-ing" behind.Diabetogenic T-cell clones recognize an altered peptide of chromogranin A.Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusionB Cell in Autoimmune Diseases.T cells interact with T cells via CD40-CD154 to promote autoimmunity in type 1 diabetes.Novel autoantigens for diabetogenic CD4 T cells in autoimmune diabetes.Cutting edge: CD4 T cells reactive to an islet amyloid polypeptide peptide accumulate in the pancreas and contribute to disease pathogenesis in nonobese diabetic mice.T cell islet accumulation in type 1 diabetes is a tightly regulated, cell-autonomous eventT Cell Repertoire Diversity Is Decreased in Type 1 Diabetes PatientsExosomes released by islet-derived mesenchymal stem cells trigger autoimmune responses in NOD mice.CD4 T cells and their antigens in the pathogenesis of autoimmune diabetes.Analysis of the rat Iddm14 diabetes susceptibility locus in multiple rat strains: identification of a susceptibility haplotype in the Tcrb-V locus.The anti-insulin trimolecular complex in type 1 diabetes.Mechanisms of diabetic autoimmunity: I--the inductive interface between islets and the immune system at onset of inflammation.Mechanisms of autoimmunity in the non-obese diabetic mouse: effector/regulatory cell equilibrium during peak inflammation.A citrullinated fibrinogen-specific T cell line enhances autoimmune arthritis in a mouse model of rheumatoid arthritis.Status of autoimmune diabetes 20-year after generation of BDC2.5-TCR transgenic non-obese diabetic mouse.Double deficiency in IL-17 and IFN-γ signalling significantly suppresses the development of diabetes in the NOD mouse.T Cell-Mediated Beta Cell Destruction: Autoimmunity and Alloimmunity in the Context of Type 1 Diabetes.Simultaneous Recognition of Allogeneic MHC and Cognate Autoantigen by Autoreactive T Cells in Transplant Rejection.An insulin-IAPP hybrid peptide is an endogenous antigen for CD4 T cells in the non-obese diabetic mouse.Recent insights into CD4+T-cell specificity and function in Type 1 diabetes
P2860
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P2860
Pathogenic T-cell clones in autoimmune diabetes: more lessons from the NOD mouse.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Pathogenic T-cell clones in autoimmune diabetes: more lessons from the NOD mouse.
@ast
Pathogenic T-cell clones in autoimmune diabetes: more lessons from the NOD mouse.
@en
type
label
Pathogenic T-cell clones in autoimmune diabetes: more lessons from the NOD mouse.
@ast
Pathogenic T-cell clones in autoimmune diabetes: more lessons from the NOD mouse.
@en
prefLabel
Pathogenic T-cell clones in autoimmune diabetes: more lessons from the NOD mouse.
@ast
Pathogenic T-cell clones in autoimmune diabetes: more lessons from the NOD mouse.
@en
P1476
Pathogenic T-cell clones in autoimmune diabetes: more lessons from the NOD mouse.
@en
P2093
Kathryn Haskins
P304
P356
10.1016/S0065-2776(05)87004-X
P577
2005-01-01T00:00:00Z