Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion
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Beta cell antigens in type 1 diabetes: triggers in pathogenesis and therapeutic targetsEnvironmental risk factors for type 1 diabetesType 1 diabetes mellitus.Pathogenic CD4+ T cells in patients with asthma.Reactive oxygen species are required for driving efficient and sustained aerobic glycolysis during CD4+ T cell activation.Dual non-contiguous peptide occupancy of HLA class I evoke antiviral human CD8 T cell response and form neo-epitopes with self-antigens.Progress and challenges for treating Type 1 diabetes.Single-cell analysis of glandular T cell receptors in Sjögren's syndrome.B Cell Receptor Affinity for Insulin Dictates Autoantigen Acquisition and B Cell Functionality in Autoimmune Diabetes.Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes.Narrowing in on the anti-β cell-specific T cells: looking 'where the action is'.Efficient Presentation of Multiple Endogenous Epitopes to Both CD4+ and CD8+ Diabetogenic T Cells for ToleranceIn Vivo Enrichment of Diabetogenic T Cells.Apportioning Blame: Autoreactive CD4+ and CD8+ T Cells in Type 1 Diabetes.Of the multiple mechanisms leading to type 1 diabetes, T cell receptor revision may play a prominent role (is type 1 diabetes more than a single disease?).Chromogranin A as biomarker in diabetes.Receptor for Advanced Glycation End Products (RAGE) in Type 1 Diabetes Pathogenesis.Restoring Regulatory T Cells in Type 1 Diabetes.Endoplasmic reticulum stress in beta cells and autoimmune diabetes.Immune targets and neoantigens for cancer immunotherapy and precision medicine.The multiple pathways to autoimmunity.Understanding type 1 diabetes through proteomics.Memory T Cells in Type 1 Diabetes: the Devil is in the Detail.Tolerogenic nanoparticles inhibit T cell-mediated autoimmunity through SOCS2.Interferon alpha impairs insulin production in human beta cells via endoplasmic reticulum stress.Rapid identification and expression of human TCRs in retrogenic mice.Antibodies to post-translationally modified insulin as a novel biomarker for prediction of type 1 diabetes in children.The Four-Way Stop Sign: Viruses, 12-Lipoxygenase, Islets, and Natural Killer Cells in Type 1 Diabetes ProgressionThe SysteMHC Atlas project.Glucose Driven Changes in Beta Cell Identity Are Important for Function and Possibly Autoimmune Vulnerability during the Progression of Type 1 Diabetes.Is Tolerance Broken in Autoimmunity?Environmental Factors Contribute to β Cell Endoplasmic Reticulum Stress and Neo-Antigen Formation in Type 1 Diabetes.T Cell Receptor Profiling in Type 1 Diabetes.Antigen-Specific Immune Modulation Targets mTORC1 Function To Drive Chemokine Receptor-Mediated T Cell Tolerance.Islet-Derived CD4 T Cells Targeting Proinsulin in Human Autoimmune Diabetes.Stacking the Deck: Studies of Patients with Multiple Autoimmune Diseases Propelled Our Understanding of Type 1 Diabetes as an Autoimmune Disease.Isogenic Cellular Systems Model the Impact of Genetic Risk Variants in the Pathogenesis of Type 1 Diabetes.C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes.CD40-mediated signalling influences trafficking, T-cell receptor expression, and T-cell pathogenesis, in the NOD model of type 1 diabetes.Avidity and Bystander Suppressive Capacity of Human Regulatory T Cells Expressing De Novo Autoreactive T-Cell Receptors in Type 1 Diabetes.
P2860
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P2860
Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion
@en
type
label
Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion
@en
prefLabel
Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion
@en
P2093
P2860
P356
P1433
P1476
Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion
@en
P2093
Alvin C Powers
Brenda Bradley
Colleen M Elso
David M Harlan
Gene Barbour
Kathryn Haskins
Megan DeNicola
Michael Armstrong
Nichole Reisdorph
Nitesh Kumar
P2860
P304
P356
10.1126/SCIENCE.AAD2791
P407
P577
2016-02-01T00:00:00Z