Murine Flt3, a gene encoding a novel tyrosine kinase receptor of the PDGFR/CSF1R family.
about
STK-1, the human homolog of Flk-2/Flt-3, is selectively expressed in CD34+ human bone marrow cells and is involved in the proliferation of early progenitor/stem cellsMegakaryocyte biology and related disordersFlk-2 is a marker in hematopoietic stem cell differentiation: a simple method to isolate long-term stem cellsShc, Grb2, Sos1, and a 150-kilodalton tyrosine-phosphorylated protein form complexes with Fms in hematopoietic cellsImmunity and Tolerance Induced by Intestinal Mucosal Dendritic CellsMutation of Tyr697, a GRB2-binding site, and Tyr721, a PI 3-kinase binding site, abrogates signal transduction by the murine CSF-1 receptor expressed in Rat-2 fibroblastsTyrosine 569 in the c-Fms juxtamembrane domain is essential for kinase activity and macrophage colony-stimulating factor-dependent internalizationStructure of Full-Length Human PDGFRβ Bound to Its Activating Ligand PDGF-B as Determined by Negative-Stain Electron Microscopy.Absence of fetal liver hematopoiesis in mice deficient in transcriptional coactivator core binding factor beta.CD133+ adult human retinal cells remain undifferentiated in Leukaemia Inhibitory Factor (LIF)RNA interference screen in primary human T cells reveals FLT3 as a modulator of IL-10 levels.Flt3-L increases CD4+CD25+Foxp3+ICOS+ cells in the lungs of cockroach-sensitized and -challenged mice.Identification of a unique membrane-bound molecule on a hemopoietic stem cell line and on multipotent progenitor cellsThe Cytokine Flt3-Ligand in Normal and Malignant HematopoiesisMolecular basis and management of gastrointestinal stromal tumorsFms-like tyrosine kinase 3 ligand decreases T helper type 17 cells and suppressors of cytokine signaling proteins in the lung of house dust mite-sensitized and -challenged mice.Long-term culture system for selective growth of human B-cell progenitors.FLT3 inhibitors in the treatment of acute myeloid leukemia: the start of an era?Coexpression of flt-3 ligand/flt-3 and SCF/c-kit signal transduction system in bile-duct-ligated SI and W mice.cDNA microarray analysis of macroregenerative and dysplastic nodules in end-stage hepatitis C virus-induced cirrhosis.Roles of tyrosine 589 and 591 in STAT5 activation and transformation mediated by FLT3-ITD.Mitogenic signalling and substrate specificity of the Flk2/Flt3 receptor tyrosine kinase in fibroblasts and interleukin 3-dependent hematopoietic cellsSmall molecule tyrosine kinase inhibitors for the treatment of intestinal inflammationIn vivo evidence for an instructive role of fms-like tyrosine kinase-3 (FLT3) ligand in hematopoietic development.Mucosal adjuvants for vaccines to control upper respiratory infections in the elderly.Platelet-derived growth factors and their receptors: structural and functional perspectives.Developmental and Functional Control of Natural Killer Cells by Cytokines.Targeting gene expression to haemopoietic stem cells: a chromatin-dependent upstream element mediates cell type-specific expression of the stem cell antigen CD34.FLT3 and FLT3-ITD phosphorylate and inactivate the cyclin-dependent kinase inhibitor p27Kip1 in acute myeloid leukemia.Flt3 ligand expands CD103⁺ dendritic cells and FoxP3⁺ T regulatory cells, and attenuates Crohn's-like murine ileitis.Selective Expression of Flt3 within the Mouse Hematopoietic Stem Cell Compartment.The Challenge of t (6;9) and FLT3-Positive Acute Myelogenous Leukemia in a Young Adult.The FLT3 ligand potently and directly stimulates the growth and expansion of primitive murine bone marrow progenitor cells in vitro: synergistic interactions with interleukin (IL) 11, IL-12, and other hematopoietic growth factors.FLT3 INHIBITORS: RECENT ADVANCES AND PROBLEMS FOR CLINICAL APPLICATION.Silencing of adaptor protein SH3BP2 reduces KIT/PDGFRA receptors expression and impairs gastrointestinal stromal tumors growth.New nucleotide sequence data on the EMBL File Server
P2860
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P2860
Murine Flt3, a gene encoding a novel tyrosine kinase receptor of the PDGFR/CSF1R family.
description
1991 nî lūn-bûn
@nan
1991 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Murine Flt3, a gene encoding a novel tyrosine kinase receptor of the PDGFR/CSF1R family.
@ast
Murine Flt3, a gene encoding a novel tyrosine kinase receptor of the PDGFR/CSF1R family.
@en
type
label
Murine Flt3, a gene encoding a novel tyrosine kinase receptor of the PDGFR/CSF1R family.
@ast
Murine Flt3, a gene encoding a novel tyrosine kinase receptor of the PDGFR/CSF1R family.
@en
prefLabel
Murine Flt3, a gene encoding a novel tyrosine kinase receptor of the PDGFR/CSF1R family.
@ast
Murine Flt3, a gene encoding a novel tyrosine kinase receptor of the PDGFR/CSF1R family.
@en
P2093
P1433
P1476
Murine Flt3, a gene encoding a novel tyrosine kinase receptor of the PDGFR/CSF1R family.
@en
P2093
Birnbaum D
Marchetto S
deLapeyriere O
P304
P407
P577
1991-09-01T00:00:00Z