Identification of type 1 inosine monophosphate dehydrogenase as an antiangiogenic drug target. - Wikidata - awgldk - TriplyDB

Identification of type 1 inosine monophosphate dehydrogenase as an antiangiogenic drug target.

Identification of type 1 inosine monophosphate dehydrogenase as an antiangiogenic drug target.

http://www.wikidata.org/entity/Q33241154

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Clofazimine inhibits human Kv1.3 potassium channel by perturbing calcium oscillation in T lymphocytes IMP dehydrogenase: structure, mechanism, and inhibition.Increased riboflavin production by manipulation of inosine 5'-monophosphate dehydrogenase in Ashbya gossypii Itraconazole, a commonly used antifungal that inhibits Hedgehog pathway activity and cancer growth Identification of cetrimonium bromide and irinotecan as compounds with synthetic lethality against NDRG1 deficient prostate cancer cells Synergistic inhibition of endothelial cell proliferation, tube formation, and sprouting by cyclosporin A and itraconazole Triazole-linked inhibitors of inosine monophosphate dehydrogenase from human and Mycobacterium tuberculosis High throughput screening for neurodegeneration and complex disease phenotypes.Identification of inhibitors of ABCG2 by a bioluminescence imaging-based high-throughput assay.One-carbon metabolism and nucleotide biosynthesis as attractive targets for anticancer therapy.Recent advances in drug repositioning for the discovery of new anticancer drugs Antiproliferative effects of AVN944, a novel inosine 5-monophosphate dehydrogenase inhibitor, in prostate cancer cells Chemical screen identifies FDA-approved drugs and target pathways that induce precocious pancreatic endocrine differentiation.Reversal of TNP-470-induced endothelial cell growth arrest by guanine and guanine nucleosides.Identification of an old antibiotic clofoctol as a novel activator of unfolded protein response pathways and an inhibitor of prostate cancer.Selective inhibition of HER2-positive breast cancer cells by the HIV protease inhibitor nelfinavir.In silico design of human IMPDH inhibitors using pharmacophore mapping and molecular docking approaches Small-molecule screening of PC3 prostate cancer cells identifies tilorone dihydrochloride to selectively inhibit cell growth based on cyclin-dependent kinase 5 expression.A High-Throughput Enzyme-Coupled Assay for SAMHD1 dNTPase.First quantitative high-throughput screen in zebrafish identifies novel pathways for increasing pancreatic β-cell mass.Pyrrolidine dithiocarbamate and diethyldithiocarbamate are active against growing and nongrowing persister Mycobacterium tuberculosis.Guanine nucleotide binding to the Bateman domain mediates the allosteric inhibition of eukaryotic IMP dehydrogenases.Nonsteroidal anti-inflammatory drug sensitizes Mycobacterium tuberculosis to endogenous and exogenous antimicrobials Paediatric use of mycophenolate mofetil.Inosine monophosphate dehydrogenase as a probe in antiviral drug discovery.Neurobiological applications of small molecule screening.Synthesis of the inosine 5'-monophosphate dehydrogenase (IMPDH) inhibitors.Production of valuable compounds by molds and yeasts.A preclinical and clinical study of mycophenolate mofetil in pancreatic cancer.DB Dehydrogenase: an online integrated structural database on enzyme dehydrogenase.Balanced production of ribosome components is required for proper G1/S transition in Saccharomyces cerevisiae.A phase I dose-ranging study of the pharmacokinetics, pharmacodynamics, safety, and tolerability of AVN944, an IMPDH inhibitor, in healthy male volunteers.Mycophenolic acid induces senescence of vascular precursor cells.Drug Repositioning for Effective Prostate Cancer Treatment.Newer human inosine 5'-monophosphate dehydrogenase 2 (hIMPDH2) inhibitors as potential anticancer agents.A Review of the Potential Utility of Mycophenolate Mofetil as a Cancer Therapeutic

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P2860

Identification of type 1 inosine monophosphate dehydrogenase as an antiangiogenic drug target.

http://www.wikidata.org/entity/Q33241154

description

2006 nî lūn-bûn

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2006 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2006 թվականի մայիսին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Identification of type 1 inosi ...... an antiangiogenic drug target.

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Identification of type 1 inosi ...... an antiangiogenic drug target.

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type

label

Identification of type 1 inosi ...... an antiangiogenic drug target.

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Identification of type 1 inosi ...... an antiangiogenic drug target.

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prefLabel

Identification of type 1 inosi ...... an antiangiogenic drug target.

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Identification of type 1 inosi ...... an antiangiogenic drug target.

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Journal of Medicinal Chemistry

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Identification of type 1 inosi ...... an antiangiogenic drug target.

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P2093

Curtis R Chong

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David J Sullivan

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David Z Qian

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Fan Pan

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Jun O Liu

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Roberto Pili

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Yongfeng Wei

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2677-2680

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scholarly article

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10.1021/JM051225T

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9

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49

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2006-05-01T00:00:00Z

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7141419

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16640327

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P921

mycophenolic acid