Mimicking damaged DNA with a small molecule inhibitor of human UNG2. - Wikidata - awgldk - TriplyDB

Mimicking damaged DNA with a small molecule inhibitor of human UNG2.

Mimicking damaged DNA with a small molecule inhibitor of human UNG2.

http://www.wikidata.org/entity/Q33261442

about

Uracil-DNA glycosylases SMUG1 and UNG2 coordinate the initial steps of base excision repair by distinct mechanisms Impact of linker strain and flexibility in the design of a fragment-based inhibitor Structure of uracil-DNA glycosylase fromMycobacterium tuberculosis: insights into interactions with ligands Structural plasticity in Mycobacterium tuberculosis uracil-DNA glycosylase (MtUng) and its functional implications Uracil-DNA glycosylase: Structural, thermodynamic and kinetic aspects of lesion search and recognition Competitive inhibition of uracil DNA glycosylase by a modified nucleotide whose triphosphate is a substrate for DNA polymerase.Inhibition of DNA glycosylases via small molecule purine analogs DNA polymerase bypass in vitro and in E. coli of a C-nucleotide analogue of Fapy-dG.Potent inhibition of human apurinic/apyrimidinic endonuclease 1 by arylstibonic acids.Vpr expression abolishes the capacity of HIV-1 infected cells to repair uracilated DNA.Probing secondary interactions in biomolecular recognition by dynamic combinatorial chemistry.Zinc finger oxidation of Fpg/Nei DNA glycosylases by 2-thioxanthine: biochemical and X-ray structural characterization.

P2860

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P2860

Mimicking damaged DNA with a small molecule inhibitor of human UNG2.

http://www.wikidata.org/entity/Q33261442

description

2006 nî lūn-bûn

@nan

2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

Mimicking damaged DNA with a small molecule inhibitor of human UNG2.

@ast

Mimicking damaged DNA with a small molecule inhibitor of human UNG2.

@en

type

label

Mimicking damaged DNA with a small molecule inhibitor of human UNG2.

@ast

Mimicking damaged DNA with a small molecule inhibitor of human UNG2.

@en

prefLabel

Mimicking damaged DNA with a small molecule inhibitor of human UNG2.

@ast

Mimicking damaged DNA with a small molecule inhibitor of human UNG2.

@en

P1433

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P1433

Nucleic Acids Research

P1476

Mimicking damaged DNA with a small molecule inhibitor of human UNG2.

@en

P2093

Daniel J Krosky

http://www.w3.org/2001/XMLSchema#string

James T Stivers

http://www.w3.org/2001/XMLSchema#string

Lauren Seiple

http://www.w3.org/2001/XMLSchema#string

Suhman Chung

http://www.w3.org/2001/XMLSchema#string

P2860

Uracil-DNA glycosylase-DNA substrate and product structures: conformational strain promotes catalytic efficiency by coupled stereoelectronic effects

hUNG2 is the major repair enzyme for removal of uracil from U:A matches, U:G mismatches, and U in single-stranded DNA, with hSMUG1 as a broad specificity backup

Linking uracil base excision repair and 5-fluorouracil toxicity in yeast

Heteronuclear NMR and crystallographic studies of wild-type and H187Q Escherichia coli uracil DNA glycosylase: electrophilic catalysis of uracil expulsion by a neutral histidine 187

Stressing-out DNA? The contribution of serine-phosphodiester interactions in catalysis by uracil DNA glycosylase

The CCP4 suite: programs for protein crystallography

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

Excision of deaminated cytosine from the vertebrate genome: role of the SMUG1 uracil-DNA glycosylase

Escherichia coli uracil DNA glycosylase: NMR characterization of the short hydrogen bond from His187 to uracil O2.

Combinatorial target-guided ligand assembly: identification of potent subtype-selective c-Src inhibitors.

P304

5872-5879

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scholarly article

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10.1093/NAR/GKL747

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20

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34

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P50

Mario A Bianchet

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2006-10-24T00:00:00Z

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6732731

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17062624

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1635321

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