Proteasome activator enhances survival of Huntington's disease neuronal model cells - Wikidata - awgldk - TriplyDB

Proteasome activator enhances survival of Huntington's disease neuronal model cells

Proteasome activator enhances survival of Huntington's disease neuronal model cells

http://www.wikidata.org/entity/Q33275949

about

Autophagy and the ubiquitin-proteasome system: collaborators in neuroprotection Proteomics in Traditional Chinese Medicine with an Emphasis on Alzheimer's Disease The Ubiquitin-Proteasome System and Molecular Chaperone Deregulation in Alzheimer's Disease Regulation of proteasome activity in health and disease Targeting several CAG expansion diseases by a single antisense oligonucleotide Upregulation of GSK3β Contributes to Brain Disorders in Elderly REGγ-knockout Mice Calcium-dependent plasma membrane repair requires m- or mu-calpain, but not calpain-3, the proteasome, or caspases.The 11S Proteasomal Activator REGγ Impacts Polyglutamine-Expanded Androgen Receptor Aggregation and Motor Neuron Viability through Distinct Mechanisms Autophagy and the ubiquitin-proteasome system in cardiac dysfunction.The over-expression of the β2 catalytic subunit of the proteasome decreases homologous recombination and impairs DNA double-strand break repair in human cells.The ubiquitin-proteasome system in neurodegenerative diseases: precipitating factor, yet part of the solution Ubiquitin/proteasome pathway impairment in neurodegeneration: therapeutic implications Proteostasis in striatal cells and selective neurodegeneration in Huntington's disease.Proteasome activation is a mechanism for pyrazolone small molecules displaying therapeutic potential in amyotrophic lateral sclerosis Integration of clearance mechanisms: the proteasome and autophagy.Inhibitory effect of b-AP15 on the 20S proteasome miR-126 contributes to Parkinson's disease by dysregulating the insulin-like growth factor/phosphoinositide 3-kinase signaling.Huntington's Disease and Striatal Signaling.MiR-126 Regulates Growth Factor Activities and Vulnerability to Toxic Insult in Neurons.Synthesis of Lithocholic Acid Derivatives as Proteasome Regulators Compensatory changes in the ubiquitin-proteasome system, brain-derived neurotrophic factor and mitochondrial complex II/III in YAC72 and R6/2 transgenic mice partially model Huntington's disease patients.Neuroprotection for Huntington's disease: ready, set, slow Proteasome regulators: activators and inhibitors.Mitochondrial permeability transition pore induces mitochondria injury in Huntington disease.The Mechanistic Links Between Proteasome Activity, Aging and Age-related Diseases.Sulforaphane enhances proteasomal and autophagic activities in mice and is a potential therapeutic reagent for Huntington's disease.Generalization of the prion hypothesis to other neurodegenerative diseases: an imperfect fit.Polyglutamine (PolyQ) diseases: genetics to treatments.Ubiquitin pathways in neurodegenerative disease.Inverse association between cancer and neurodegenerative disease: review of the epidemiologic and biological evidence.The role of protein clearance mechanisms in organismal ageing and age-related diseases.Walking the tightrope: proteostasis and neurodegenerative disease.Life and death in the trash heap: The ubiquitin proteasome pathway and UCHL1 in brain aging, neurodegenerative disease and cerebral Ischemia.The Ubiquitin Receptor ADRM1 Modulates HAP40-Induced Proteasome Activity.Interplay between the ubiquitin-proteasome system and autophagy in proteinopathies.Activation and inhibition of the proteasome by betulinic acid and its derivatives.Biological networks in Parkinson's disease: an insight into the epigenetic mechanisms associated with this disease Proteostasis of Huntingtin in Health and Disease The Ubiquitin-Proteasome System in Huntington's Disease: Are Proteasomes Impaired, Initiators of Disease, or Coming to the Rescue?Defective Protein Catabolism in Atherosclerotic Vascular Inflammation.

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P2860

Proteasome activator enhances survival of Huntington's disease neuronal model cells

http://www.wikidata.org/entity/Q33275949

description

2007 nî lūn-bûn

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2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի փետրվարին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

Proteasome activator enhances survival of Huntington's disease neuronal model cells

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Proteasome activator enhances survival of Huntington's disease neuronal model cells

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type

label

Proteasome activator enhances survival of Huntington's disease neuronal model cells

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Proteasome activator enhances survival of Huntington's disease neuronal model cells

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prefLabel

Proteasome activator enhances survival of Huntington's disease neuronal model cells

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Proteasome activator enhances survival of Huntington's disease neuronal model cells

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Proteasome activator enhances survival of Huntington's disease neuronal model cells

@en

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Hyemyung Seo

http://www.w3.org/2001/XMLSchema#string

Kai-Christian Sonntag

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Woori Kim

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P2860

Huntington's disease genetics

The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction

Structure and functions of the 20S and 26S proteasomes

Yeast counterparts of subunits S5a and p58 (S3) of the human 26S proteasome are encoded by two multicopy suppressors of nin1-1

A gated channel into the proteasome core particle

Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form

Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease

The caspase-like sites of proteasomes, their substrate specificity, new inhibitors and substrates, and allosteric interactions with the trypsin-like sites.

The proteasome, a novel protease regulated by multiple mechanisms.

Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery.

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