Signal transducer and activator of transcription 3 is involved in cell growth and survival of human rhabdomyosarcoma and osteosarcoma cells - Wikidata - awgldk - TriplyDB

Signal transducer and activator of transcription 3 is involved in cell growth and survival of human rhabdomyosarcoma and osteosarcoma cells

Signal transducer and activator of transcription 3 is involved in cell growth and survival of human rhabdomyosarcoma and osteosarcoma cells

http://www.wikidata.org/entity/Q33289241

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Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models.Characterization of STAT3 activation and expression in canine and human osteosarcoma.Small interfering RNA library screen of human kinases and phosphatases identifies polo-like kinase 1 as a promising new target for the treatment of pediatric rhabdomyosarcomas.Oleanane triterpenoid CDDO-Me induces apoptosis in multidrug resistant osteosarcoma cells through inhibition of Stat3 pathway STAT inhibitors for cancer therapy.Repositioning Bazedoxifene as a novel IL-6/GP130 signaling antagonist for human rhabdomyosarcoma therapy Anti-angiogenic activity of a small molecule STAT3 inhibitor LLL12.Initial solid tumor testing (stage 1) of AZD1480, an inhibitor of Janus kinases 1 and 2 by the pediatric preclinical testing program.The novel curcumin analog FLLL32 decreases STAT3 DNA binding activity and expression, and induces apoptosis in osteosarcoma cell lines Prognostic significance of STAT3 and phosphorylated STAT3 in human soft tissue tumors - a clinicopathological analysis Human parvovirus B19 NS1 protein modulates inflammatory signaling by activation of STAT3/PIAS3 in human endothelial cells.Signal transducer and activator of transcription 3 activation is associated with bladder cancer cell growth and survival.Inhibition of STAT3 with orally active JAK inhibitor, AZD1480, decreases tumor growth in Neuroblastoma and Pediatric Sarcomas In vitro and In vivo Targeting STAT3 inhibits growth and enhances radiosensitivity in head and neck squamous cell carcinoma Cross talk of signals between EGFR and IL-6R through JAK2/STAT3 mediate epithelial-mesenchymal transition in ovarian carcinomas.Intestinal phenotype in mice overexpressing a heparin-binding EGF-like growth factor transgene in enterocytes.Ameloblastin induces tumor suppressive phenotype and enhances chemosensitivity to doxorubicin via Src-Stat3 inactivation in osteosarcoma.Inflammation: what role in pediatric cancer?Proof-of-concept rare cancers in drug development: the case for rhabdomyosarcoma.Canine osteosarcoma: a naturally occurring disease to inform pediatric oncology.Current and future intratumoral targeted treatment for pancreatic cancer.Target specificity, in vivo pharmacokinetics, and efficacy of the putative STAT3 inhibitor LY5 in osteosarcoma, Ewing's sarcoma, and rhabdomyosarcoma.CXCL12 suppresses cisplatin-induced apoptosis through activation of JAK2/STAT3 signaling in human non-small-cell lung cancer cells.Role of interleukin-6 in cancer progression and therapeutic resistance.Fluorofenidone protects against renal fibrosis by inhibiting STAT3 tyrosine phosphorylation.STAT3 activation in infection and infection-associated cancer.Biologic activity of the novel small molecule STAT3 inhibitor LLL12 against canine osteosarcoma cell lines.Up-regulation of Anxa2 gene promotes proliferation and invasion of breast cancer MCF-7 cells.Novel small molecule, XZH-5, inhibits constitutive and interleukin-6-induced STAT3 phosphorylation in human rhabdomyosarcoma cells.Small molecules, LLL12 and FLLL32, inhibit STAT3 and exhibit potent growth suppressive activity in osteosarcoma cells and tumor growth in mice.Persistent GP130/STAT3 Signaling Contributes to the Resistance of Doxorubicin, Cisplatin, and MEK Inhibitor in Human Rhabdomyosarcoma Cells.Expressional STAT3/STAT5 Ratio is an Independent Prognostic Marker in Colon Carcinoma.Mice lacking dystrophin or alpha sarcoglycan spontaneously develop embryonal rhabdomyosarcoma with cancer-associated p53 mutations and alternatively spliced or mutant Mdm2 transcripts.Identification and analysis of key genes in osteosarcoma using bioinformatics.Targeting the IL-6/JAK/STAT3 signalling axis in cancer.GADD45A and CDKN1A are involved in apoptosis and cell cycle modulatory effects of viscumTT with further inactivation of the STAT3 pathway.PPP2R1A regulated by PAX3/FOXO1 fusion contributes to the acquisition of aggressive behavior in PAX3/FOXO1-positive alveolar rhabdomyosarcoma.PI3K/AKT inhibition induces compensatory activation of the MET/STAT3 pathway in non-small cell lung cancer.The immune environment of paediatric solid malignancies: evidence from an immunohistochemical study of clinical cases

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Signal transducer and activator of transcription 3 is involved in cell growth and survival of human rhabdomyosarcoma and osteosarcoma cells

http://www.wikidata.org/entity/Q33289241

description

2007 nî lūn-bûn

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2007 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2007年の論文

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Signal transducer and activato ...... sarcoma and osteosarcoma cells

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Signal transducer and activato ...... sarcoma and osteosarcoma cells

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Signal transducer and activato ...... sarcoma and osteosarcoma cells

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Signal transducer and activato ...... sarcoma and osteosarcoma cells

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Signal transducer and activato ...... sarcoma and osteosarcoma cells

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Signal transducer and activato ...... sarcoma and osteosarcoma cells

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Abbey Loy

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Bryant Wu

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Christina Chan

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Chun-Liang Chen

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Fu-Chuan Hsieh

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Gong Cheng

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Jiayuh Lin

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Keiko Yamauchi-Takihara

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Keita Kunisada

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Ling Cen

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P2860

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

HOXA5-induced apoptosis in breast cancer cells is mediated by caspases 2 and 8

Signal transducer and activator of transcription 3 (STAT3) activation in prostate cancer: Direct STAT3 inhibition induces apoptosis in prostate cancer lines.

The STATs of cancer--new molecular targets come of age

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

Transcriptional responses to polypeptide ligands: the JAK-STAT pathway

A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles.

Stat3 activation is required for cellular transformation by v-src.

Progestins induce transcriptional activation of signal transducer and activator of transcription 3 (Stat3) via a Jak- and Src-dependent mechanism in breast cancer cells

A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells.

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