Distinct turnover of alternatively spliced isoforms of the RET kinase receptor mediated by differential recruitment of the Cbl ubiquitin ligase.
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GDNF-Ret signaling in midbrain dopaminergic neurons and its implication for Parkinson diseaseMolecular mechanisms of RET-induced Hirschsprung pathogenesisEnigma prevents Cbl-c-mediated ubiquitination and degradation of RETMEN2ABex1, a novel interactor of the p75 neurotrophin receptor, links neurotrophin signaling to the cell cycleCD2-associated protein (CD2AP) enhances casitas B lineage lymphoma-3/c (Cbl-3/c)-mediated Ret isoform-specific ubiquitination and degradation via its amino-terminal Src homology 3 domains.The differential axonal degradation of Ret accounts for cell-type-specific function of glial cell line-derived neurotrophic factor as a retrograde survival factor.Phosphotyrosine 1062 is critical for the in vivo activity of the Ret9 receptor tyrosine kinase isoform.Negative Regulation of Receptor Tyrosine Kinase (RTK) Signaling: A Developing FieldAlternative splicing in oncogenic kinases: from physiological functions to cancerMolecular pathways: cbl proteins in tumorigenesis and antitumor immunity-opportunities for cancer treatment.Alternative splicing results in RET isoforms with distinct trafficking properties.Brain ischemia downregulates the neuroprotective GDNF-Ret signaling by a calpain-dependent mechanism in cultured hippocampal neurons.Neurotrophic factor receptor RET: structure, cell biology, and inherited diseases.Genetic and epigenetic factors affect RET gene expression in breast cancer cell lines and influence survival in patients.Structural implication of splicing stochasticsCD2AP and Cbl-3/Cbl-c constitute a critical checkpoint in the regulation of ret signal transduction.Molecular mechanisms of RET receptor-mediated oncogenesis in multiple endocrine neoplasia 2.The RET oncogene in papillary thyroid carcinoma.Differential recruitment of E3-ubiquitin ligase complexes regulates RET isoform internalization.Optimal doses of EGF and GDNF act as biological response modifiers to improve porcine oocyte maturation and quality.Protein-tyrosine phosphatase SHP2 contributes to GDNF neurotrophic activity through direct binding to phospho-Tyr687 in the RET receptor tyrosine kinase.Cellular localization of GDNF and its GFRalpha1/RET receptor complex in the developing pancreas of cat.NGF augments the autophosphorylation of Ret via inhibition of ubiquitin-dependent degradation.Engineering the recruitment of phosphotyrosine binding domain-containing adaptor proteins reveals distinct roles for RET receptor-mediated cell survival.Extended Synaptotagmin Interaction with the Fibroblast Growth Factor Receptor Depends on Receptor Conformation, Not Catalytic Activity.Analysis of Newly Identified and Rare Synonymous Genetic Variants in the RET Gene in Patients with Medullary Thyroid Carcinoma in Polish Population.Endocytosis and cancer.Manganese-Mediated Decrease in Levels of c-RET and Tyrosine Hydroxylase Expression In Vitro.
P2860
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P2860
Distinct turnover of alternatively spliced isoforms of the RET kinase receptor mediated by differential recruitment of the Cbl ubiquitin ligase.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Distinct turnover of alternati ...... t of the Cbl ubiquitin ligase.
@ast
Distinct turnover of alternati ...... t of the Cbl ubiquitin ligase.
@en
type
label
Distinct turnover of alternati ...... t of the Cbl ubiquitin ligase.
@ast
Distinct turnover of alternati ...... t of the Cbl ubiquitin ligase.
@en
prefLabel
Distinct turnover of alternati ...... t of the Cbl ubiquitin ligase.
@ast
Distinct turnover of alternati ...... t of the Cbl ubiquitin ligase.
@en
P2093
P2860
P356
P1476
Distinct turnover of alternati ...... t of the Cbl ubiquitin ligase.
@en
P2093
Carlos F Ibáñez
Helena Aineskog
Susanna Eketjäll
P2860
P304
13442-13449
P356
10.1074/JBC.M500507200
P407
P577
2005-01-27T00:00:00Z