Karyopherin-alpha2 protein interacts with Chk2 and contributes to its nuclear import.
about
Prognostic value of increased KPNA2 expression in some solid tumors: A systematic review and meta-analysisThe FHA domain determines Drosophila Chk2/Mnk localization to key mitotic structures and is essential for early embryonic DNA damage responses.Identification of two poorly prognosed ovarian carcinoma subtypes associated with CHEK2 germ-line mutation and non-CHEK2 somatic mutation gene signatures.Human cytomegalovirus inhibits a DNA damage response by mislocalizing checkpoint proteinsHepatitis C virus NS2 protein inhibits DNA damage pathway by sequestering p53 to the cytoplasm.CHK2 kinase in the DNA damage response and beyondDifferential roles of ATM- and Chk2-mediated phosphorylations of Hdmx in response to DNA damage.KPNA2 is a nuclear export protein that contributes to aberrant localisation of key proteins and poor prognosis of breast cancerQuantitative proteomics reveals regulation of karyopherin subunit alpha-2 (KPNA2) and its potential novel cargo proteins in nonsmall cell lung cancer.MiR-26b/KPNA2 axis inhibits epithelial ovarian carcinoma proliferation and metastasis through downregulating OCT4.Low cytoplasmic and nuclear KPNA2 expression in radiotherapy-treated head and neck squamous cell cancer is associated with an adverse outcome.KPNA2 promotes cell proliferation and tumorigenicity in epithelial ovarian carcinoma through upregulation of c-Myc and downregulation of FOXO3a.Low Doses of Cisplatin Induce Gene Alterations, Cell Cycle Arrest, and Apoptosis in Human Promyelocytic Leukemia CellsMicroRNA-567 dysregulation contributes to carcinogenesis of breast cancer, targeting tumor cell proliferation, and migration.Importin β-dependent nuclear import of TopBP1 in ATR-Chk1 checkpoint in Xenopus egg extracts.CCAR2/DBC1 is required for Chk2-dependent KAP1 phosphorylation and repair of DNA damage.Chk2 and REGγ-dependent DBC1 regulation in DNA damage induced apoptosis.Negative regulation of CHK2 activity by protein phosphatase 2A is modulated by DNA damage.Intrinsic kinase activity and SQ/TQ domain of Chk2 kinase as well as N-terminal domain of Wip1 phosphatase are required for regulation of Chk2 by Wip1.Importin KPNA2 is required for proper nuclear localization and multiple functions of NBS1.Mismatch repair system decreases cell survival by stabilizing the tetraploid G1 arrest in response to SN-38.Clinical and biological significance of RAD51 expression in breast cancer: a key DNA damage response protein.Overexpression of KPNA2 correlates with poor prognosis in patients with gastric adenocarcinoma.Nuclear karyopherin a2: a novel biomarker for infiltrative astrocytomas.Silencing of the nucleocytoplasmic shuttling protein karyopherin a2 promotes cell-cycle arrest and apoptosis in glioblastoma multiforme
P2860
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P2860
Karyopherin-alpha2 protein interacts with Chk2 and contributes to its nuclear import.
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Karyopherin-alpha2 protein interacts with Chk2 and contributes to its nuclear import.
@ast
Karyopherin-alpha2 protein interacts with Chk2 and contributes to its nuclear import.
@en
type
label
Karyopherin-alpha2 protein interacts with Chk2 and contributes to its nuclear import.
@ast
Karyopherin-alpha2 protein interacts with Chk2 and contributes to its nuclear import.
@en
prefLabel
Karyopherin-alpha2 protein interacts with Chk2 and contributes to its nuclear import.
@ast
Karyopherin-alpha2 protein interacts with Chk2 and contributes to its nuclear import.
@en
P2093
P2860
P50
P356
P1476
Karyopherin-alpha2 protein interacts with Chk2 and contributes to its nuclear import
@en
P2093
Claudio Schneider
Domenico Delia
Sofia Lisanti
P2860
P304
42346-42351
P356
10.1074/JBC.M303304200
P407
P577
2003-08-09T00:00:00Z