Enteropathogenic E. coli Tir binds Nck to initiate actin pedestal formation in host cells.
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Phosphorylation of tyrosine 291 enhances the ability of WASp to stimulate actin polymerization and filopodium formation. Wiskott-Aldrich Syndrome proteinNck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytesThe EHEC-host interactome reveals novel targets for the translocated intimin receptorInsulin receptor tyrosine kinase substrate links the E. coli O157:H7 actin assembly effectors Tir and EspF(U) during pedestal formationDistinct phosphorylation requirements regulate cortactin activation by TirEPEC and its binding to N-WASPInvolvement of the Arp2/3 complex and Scar2 in Golgi polarity in scratch wound modelsA chlamydial type III translocated protein is tyrosine-phosphorylated at the site of entry and associated with recruitment of actinThe murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin networkEpithelial Intermediate Filaments: Guardians against Microbial Infection?Effector triggered manipulation of host immune response elicited by different pathotypes of Escherichia coliPlexin-B2 negatively regulates macrophage motility, Rac, and Cdc42 activationStructural basis for complex formation between human IRSp53 and the translocated intimin receptor Tir of enterohemorrhagic E. coli.Proteomic discovery of host kinase signaling in bacterial infectionsInteraction domains: from simple binding events to complex cellular behaviorDisabling poxvirus pathogenesis by inhibition of Abl-family tyrosine kinasesHigh-throughput analysis of peptide-binding modulesOncogenic mechanisms of the Helicobacter pylori CagA proteinCytosolic extract induces Tir translocation and pedestals in EPEC-infected red blood cellsThe adaptor molecule Nck localizes the WAVE complex to promote actin polymerization during CEACAM3-mediated phagocytosis of bacteriac-Abl phosphorylates Dok1 to promote filopodia during cell spreadingEnteropathogenic Escherichia coli and vaccinia virus do not require the family of WASP-interacting proteins for pathogen-induced actin assemblyNeph1 cooperates with nephrin to transduce a signal that induces actin polymerizationAllosteric N-WASP activation by an inter-SH3 domain linker in NckConserved interdomain linker promotes phase separation of the multivalent adaptor protein Nck.Nck adaptors, besides promoting N-WASP mediated actin-nucleation activity at pedestals, influence the cellular levels of enteropathogenic Escherichia coli Tir effector.WIP provides an essential link between Nck and N-WASP during Arp2/3-dependent actin polymerization.Nck adaptors are positive regulators of the size and sensitivity of the T-cell repertoire.Nck adaptor proteins link Tks5 to invadopodia actin regulation and ECM degradation.Nck adapter proteins: functional versatility in T cellsThe phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains.Cortactin is essential for F-actin assembly in enteropathogenic Escherichia coli (EPEC)- and enterohaemorrhagic E. coli (EHEC)-induced pedestals and the alpha-helical region is involved in the localization of cortactin to bacterial attachment sites.Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization.Nck-dependent activation of extracellular signal-regulated kinase-1 and regulation of cell survival during endoplasmic reticulum stress.A C-terminal class I PDZ binding motif of EspI/NleA modulates the virulence of attaching and effacing Escherichia coli and Citrobacter rodentium.Effect of protein kinase A-mediated phosphorylation on the structure and association properties of the enteropathogenic Escherichia coli Tir virulence protein.Involvement of the intermediate filament protein cytokeratin-18 in actin pedestal formation during EPEC infection.The localized adherence pattern of an atypical enteropathogenic Escherichia coli is mediated by intimin omicron and unexpectedly promotes HeLa cell invasion.All blood, no stool: enterohemorrhagic Escherichia coli O157:H7 infection.The T3SS effector EspT defines a new category of invasive enteropathogenic E. coli (EPEC) which form intracellular actin pedestals.Dissecting the role of the Tir:Nck and Tir:IRTKS/IRSp53 signalling pathways in vivo
P2860
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P2860
Enteropathogenic E. coli Tir binds Nck to initiate actin pedestal formation in host cells.
description
2001 nî lūn-bûn
@nan
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Enteropathogenic E. coli Tir b ...... estal formation in host cells.
@ast
Enteropathogenic E. coli Tir b ...... estal formation in host cells.
@en
Enteropathogenic E. coli Tir b ...... estal formation in host cells.
@nl
type
label
Enteropathogenic E. coli Tir b ...... estal formation in host cells.
@ast
Enteropathogenic E. coli Tir b ...... estal formation in host cells.
@en
Enteropathogenic E. coli Tir b ...... estal formation in host cells.
@nl
prefLabel
Enteropathogenic E. coli Tir b ...... estal formation in host cells.
@ast
Enteropathogenic E. coli Tir b ...... estal formation in host cells.
@en
Enteropathogenic E. coli Tir b ...... estal formation in host cells.
@nl
P2093
P356
P1433
P1476
Enteropathogenic E. coli Tir b ...... estal formation in host cells.
@en
P2093
DeVinney R
Gruenheid S
P2888
P304
P356
10.1038/NCB0901-856
P577
2001-09-01T00:00:00Z
P6179
1029438507