Dissecting the role of the Tir:Nck and Tir:IRTKS/IRSp53 signalling pathways in vivo
about
Nck adaptors, besides promoting N-WASP mediated actin-nucleation activity at pedestals, influence the cellular levels of enteropathogenic Escherichia coli Tir effector.Indispensable functions of ABL and PDGF receptor kinases in epithelial adherence of attaching/effacing pathogens under physiological conditions.The ability of an attaching and effacing pathogen to trigger localized actin assembly contributes to virulence by promoting mucosal attachment.Enteropathogenic and enterohaemorrhagic Escherichia coli: even more subversive elements.Actin pedestal formation by enterohemorrhagic Escherichia coli enhances bacterial host cell attachment and concomitant type III translocationContribution of Crk adaptor proteins to host cell and bacteria interactions.Enteropathogenic and enterohemorrhagic Escherichia coli type III secretion effector EspV induces radical morphological changes in eukaryotic cells.Crk adaptors negatively regulate actin polymerization in pedestals formed by enteropathogenic Escherichia coli (EPEC) by binding to Tir effector.Bacterial subversion of host actin dynamics at the plasma membrane.Allele- and tir-independent functions of intimin in diverse animal infection modelsTir Triggers Expression of CXCL1 in Enterocytes and Neutrophil Recruitment during Citrobacter rodentium InfectionCitrobacter rodentium mouse model of bacterial infection.The L-Arginine Transporter Solute Carrier Family 7 Member 2 Mediates the Immunopathogenesis of Attaching and Effacing Bacteria.Pre-treatment with Bifidobacterium breve UCC2003 modulates Citrobacter rodentium-induced colonic inflammation and organ specificity.Deficiency of IRTKS as an adaptor of insulin receptor leads to insulin resistance.Infection strategies of enteric pathogenic Escherichia coli.Intimate host attachment: enteropathogenic and enterohaemorrhagic Escherichia coli.Extracellular motility and cell-to-cell transmission of enterohemorrhagic E. coli is driven by EspFU-mediated actin assembly.The Enterohemorrhagic Escherichia coli Effector EspW Triggers Actin Remodeling in a Rac1-Dependent Manner.Calpain mediates epithelial cell microvillar effacement by enterohemorrhagic Escherichia coli.Type III Secreted Virulence Factors Manipulating Signaling to Actin Dynamics.Enhanced Actin Pedestal Formation by Enterohemorrhagic Escherichia coli O157:H7 Adapted to the Mammalian HostThe enteropathogenic E. coli effector EspH promotes actin pedestal formation and elongation via WASP-interacting protein (WIP).4D multimodality imaging of Citrobacter rodentium infections in mice.Actin cytoskeleton manipulation by effector proteins secreted by diarrheagenic Escherichia coli pathotypes.Citrobacter rodentium Relies on Commensals for Colonization of the Colonic Mucosa.Attaching-and-Effacing Pathogens Exploit Junction Regulatory Activities of N-WASP and SNX9 to Disrupt the Intestinal Barrier.IRTKS (BAIAP2L1) Elongates Epithelial Microvilli Using EPS8-Dependent and Independent Mechanisms
P2860
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P2860
Dissecting the role of the Tir:Nck and Tir:IRTKS/IRSp53 signalling pathways in vivo
description
2009 nî lūn-bûn
@nan
2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Dissecting the role of the Tir:Nck and Tir:IRTKS/IRSp53 signalling pathways in vivo
@ast
Dissecting the role of the Tir:Nck and Tir:IRTKS/IRSp53 signalling pathways in vivo
@en
type
label
Dissecting the role of the Tir:Nck and Tir:IRTKS/IRSp53 signalling pathways in vivo
@ast
Dissecting the role of the Tir:Nck and Tir:IRTKS/IRSp53 signalling pathways in vivo
@en
prefLabel
Dissecting the role of the Tir:Nck and Tir:IRTKS/IRSp53 signalling pathways in vivo
@ast
Dissecting the role of the Tir:Nck and Tir:IRTKS/IRSp53 signalling pathways in vivo
@en
P2093
P2860
P50
P1476
Dissecting the role of the Tir:Nck and Tir:IRTKS/IRSp53 signalling pathways in vivo
@en
P2093
Alan D Phillips
Francis Girard
Valérie F Crepin
P2860
P304
P356
10.1111/J.1365-2958.2009.06938.X
P407
P577
2009-11-02T00:00:00Z