Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function. - Wikidata - awgldk - TriplyDB

Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function.

Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function.

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Polymorphisms within the novel type 2 diabetes risk locus MTNR1B determine beta-cell function Systematic identification of interaction effects between genome- and environment-wide associations in type 2 diabetes mellitus Physiologic characterization of type 2 diabetes-related loci Genetic variation and exercise-induced muscle damage: implications for athletic performance, injury and ageing Novel phenotypes of prediabetes?Different role of zinc transporter 8 between type 1 diabetes mellitus and type 2 diabetes mellitus Zinc transporter 8 (ZnT8) and β cell function Zinc and zinc transporter regulation in pancreatic islets and the potential role of zinc in islet transplantation Down-regulation of ZnT8 expression in INS-1 rat pancreatic beta cells reduces insulin content and glucose-inducible insulin secretion Evaluation of fasting state-/oral glucose tolerance test-derived measures of insulin release for the detection of genetically impaired β-cell function Gene expression in skeletal muscle biopsies from people with type 2 diabetes and relatives: differential regulation of insulin signaling pathways Genome-wide association studies in type 2 diabetes Genetic mapping in human disease Novel meta-analysis-derived type 2 diabetes risk loci do not determine prediabetic phenotypes.Variance of the SGK1 gene is associated with insulin secretion in different European populations: results from the TUEF, EUGENE2, and METSIM studies.Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data Novel association of HK1 with glycated hemoglobin in a non-diabetic population: a genome-wide evaluation of 14,618 participants in the Women's Genome Health Study.Investigation of type 2 diabetes risk alleles support CDKN2A/B, CDKAL1, and TCF7L2 as susceptibility genes in a Han Chinese cohort.Zinc transporters and their role in the pancreatic β-cell.Association of COL4A3 (rs55703767), MMP-9 (rs17576)and TIMP-1 (rs6609533) gene polymorphisms with susceptibility to type 2 diabetes The longitudinal association of common susceptibility variants for type 2 diabetes and obesity with fasting glucose level and BMI.Combined effects of 19 common variations on type 2 diabetes in Chinese: results from two community-based studies Genetics of type 2 diabetes in European populations.Genetic variants of IDE-KIF11-HHEX at 10q23.33 associated with type 2 diabetes risk: a fine-mapping study in Chinese population.Polymorphism rs11085226 in the gene encoding polypyrimidine tract-binding protein 1 negatively affects glucose-stimulated insulin secretion.Total zinc intake may modify the glucose-raising effect of a zinc transporter (SLC30A8) variant: a 14-cohort meta-analysis.Contribution of SLC30A8 variants to the risk of type 2 diabetes in a multi-ethnic population: a case control study.Association between SLC30A8 rs13266634 Polymorphism and Type 2 Diabetes Risk: A Meta-Analysis.Zinc transporter 8 autoantibodies and their association with SLC30A8 and HLA-DQ genes differ between immigrant and Swedish patients with newly diagnosed type 1 diabetes in the Better Diabetes Diagnosis study Znt7-null mice are more susceptible to diet-induced glucose intolerance and insulin resistance.Interactions between genetic background, insulin resistance and β-cell function.SLC30A8 (ZnT8) Polymorphism is Associated with Young Age at Type 1 Diabetes Onset.Extension of type 2 diabetes genome-wide association scan results in the diabetes prevention program Diabetes genes identified by genome-wide association studies are regulated in mice by nutritional factors in metabolically relevant tissues and by glucose concentrations in islets.A common nonsynonymous single nucleotide polymorphism in the SLC30A8 gene determines ZnT8 autoantibody specificity in type 1 diabetes.Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population.Cholesterol in islet dysfunction and type 2 diabetes Genetic Variation and Insulin Resistance in Middle-Aged Chinese Men Genetic variant in the IGF2BP2 gene may interact with fetal malnutrition to affect glucose metabolism.Association of type 2 diabetes candidate polymorphisms in KCNQ1 with incretin and insulin secretion.

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Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function.

http://www.wikidata.org/entity/Q33296991

description

2007 nî lūn-bûn

@nan

2007 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

name

Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function.

@ast

Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function.

@en

Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function.

@nl

type

label

Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function.

@ast

Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function.

@en

Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function.

@nl

prefLabel

Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function.

@ast

Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function.

@en

Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function.

@nl

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JOURNAL.PONE.0000832

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Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function.

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Andreas Fritsche

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Claus Thamer

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Fausto Machicao

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Kerstin Kirchhoff

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Konstantinos Kantartzis

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Otto Tschritter

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Silke A Schäfer

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P2860

The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules

In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion

Candidate gene association study in type 2 diabetes indicates a role for genes involved in beta-cell function as well as insulin action

A genome-wide association study identifies novel risk loci for type 2 diabetes

Hex homeobox gene controls the transition of the endoderm to a pseudostratified, cell emergent epithelium for liver bud development

Hex homeobox gene-dependent tissue positioning is required for organogenesis of the ventral pancreas

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

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10.1371/JOURNAL.PONE.0000832

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9

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2

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Hans-Ulrich Häring

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2007-09-05T00:00:00Z

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6054735

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17786204

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type-2 diabetes

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1952072

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