Solution structure of the second bromodomain of Brd2 and its specific interaction with acetylated histone tails
about
Structural implications for K5/K12-di-acetylated histone H4 recognition by the second bromodomain of BRD2Histone recognition and large-scale structural analysis of the human bromodomain familyThe role of human bromodomains in chromatin biology and gene transcriptionStructural Basis for Acetylated Histone H4 Recognition by the Human BRD2 BromodomainSuppression of inflammation by a synthetic histone mimicA combination of H2A.Z and H4 acetylation recruits Brd2 to chromatin during transcriptional activationThe testis-specific double bromodomain-containing protein BRDT forms a complex with multiple spliceosome components and is required for mRNA splicing and 3'-UTR truncation in round spermatidsA Novel Phenanthridionone Based Scaffold As a Potential Inhibitor of the BRD2 Bromodomain: Crystal Structure of the ComplexThe C-terminal domain of Brd2 is important for chromatin interaction and regulation of transcription and alternative splicing.The "histone mimicry" by pathogens.Epigenetic drugs against cancer: an evolving landscape.Development of neurodevelopmental disorders: a regulatory mechanism involving bromodomain-containing proteinsThe bromodomain inhibitor N-methyl pyrrolidone reduced fat accumulation in an ovariectomized rat model.The interaction of the gammaherpesvirus 68 orf73 protein with cellular BET proteins affects the activation of cell cycle promoters.Bromo- and extraterminal domain chromatin regulators serve as cofactors for murine leukemia virus integration.Double bromodomain-containing gene Brd2 is essential for embryonic development in mouseThe role of the double bromodomain-containing BET genes during mammalian spermatogenesis.Bromodomains as therapeutic targets.The bromodomain interaction module.The promise and failures of epigenetic therapies for cancer treatmentInhibition of bromodomain and extra-terminal proteins (BET) as a potential therapeutic approach in haematological malignancies: emerging preclinical and clinical evidence.New Synthetic Routes to Triazolo-benzodiazepine Analogues: Expanding the Scope of the Bump-and-Hole Approach for Selective Bromo and Extra-Terminal (BET) Bromodomain Inhibition.Bromodomain and extra-terminal (BET) family proteins: New therapeutic targets in major diseases.HIV-1 Tat Binding to PCAF Bromodomain: Structural Determinants from Computational Methods.Molecular structures guide the engineering of chromatin.Exploiting a water network to achieve enthalpy-driven, bromodomain-selective BET inhibitors.Insights into the crystal structure of BRD2-BD2 - phenanthridinone complex and theoretical studies on phenanthridinone analogs.Bromodomain-peptide displacement assays for interactome mapping and inhibitor discovery
P2860
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P2860
Solution structure of the second bromodomain of Brd2 and its specific interaction with acetylated histone tails
description
2007 nî lūn-bûn
@nan
2007 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Solution structure of the seco ...... with acetylated histone tails
@ast
Solution structure of the seco ...... with acetylated histone tails
@en
Solution structure of the seco ...... with acetylated histone tails.
@nl
type
label
Solution structure of the seco ...... with acetylated histone tails
@ast
Solution structure of the seco ...... with acetylated histone tails
@en
Solution structure of the seco ...... with acetylated histone tails.
@nl
prefLabel
Solution structure of the seco ...... with acetylated histone tails
@ast
Solution structure of the seco ...... with acetylated histone tails
@en
Solution structure of the seco ...... with acetylated histone tails.
@nl
P2093
P2860
P356
P1476
Solution structure of the seco ...... with acetylated histone tails
@en
P2093
Hongda Huang
Jiahai Zhang
Weiqun Shen
Xingsheng Wang
P2860
P2888
P356
10.1186/1472-6807-7-57
P577
2007-09-12T00:00:00Z
P5875
P6179
1038087578