Constitutive phosphorylation of aurora-a on ser51 induces its stabilization and consequent overexpression in cancer
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Non-centrosomal TPX2-Dependent Regulation of the Aurora A Kinase: Functional Implications for Healthy and Pathological Cell DivisionUbiquitin-Mediated Degradation of Aurora KinasesAurora-A Kinase as a Promising Therapeutic Target in CancerThe Non-Canonical Role of Aurora-A in DNA ReplicationBPR1K653, a novel Aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cellsAurora kinases in head and neck cancerAurora-A controls pre-replicative complex assembly and DNA replication by stabilizing geminin in mitosis.Evidence toward a dual phosphatase mechanism that restricts Aurora A (Thr-295) phosphorylation during the early embryonic cell cycle.Control of centrin stability by Aurora A.Single nucleotide polymorphisms in AREG and EREG are prognostic biomarkers in locally advanced gastric cancer patients after surgery with curative intent.Aurora-A inactivation causes mitotic spindle pole fragmentation by unbalancing microtubule-generated forcesOverexpression of Aurora-A promotes laryngeal cancer progression by enhancing invasive ability and chromosomal instabilityThe APC/C Ubiquitin Ligase: From Cell Biology to TumorigenesisProtein tyrosine phosphatase receptor delta acts as a neuroblastoma tumor suppressor by destabilizing the aurora kinase A oncogene.State of the APC/C: organization, function, and structure.Heterogeneity in sarcoma cell lines reveals enhanced motility of tetraploid versus diploid cells.APC/C-Cdh1: from cell cycle to cellular differentiation and genomic integrity.Aurora kinase inhibitor patents and agents in clinical testing: an update (2009-10).Aurora kinase inhibitor patents and agents in clinical testing: an update (2011 - 2013).Multi-kinase inhibitors, AURKs and cancer.HIF-1 is involved in the negative regulation of AURKA expression in breast cancer cell lines under hypoxic conditions.Common variation at BARD1 results in the expression of an oncogenic isoform that influences neuroblastoma susceptibility and oncogenicity.Control of Aurora-A stability through interaction with TPX2.A SUMOylation Motif in Aurora-A: Implications for Spindle Dynamics and Oncogenesis.Kinases and cancer
P2860
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P2860
Constitutive phosphorylation of aurora-a on ser51 induces its stabilization and consequent overexpression in cancer
description
2007 nî lūn-bûn
@nan
2007 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Constitutive phosphorylation o ...... quent overexpression in cancer
@ast
Constitutive phosphorylation o ...... quent overexpression in cancer
@en
Constitutive phosphorylation o ...... uent overexpression in cancer.
@nl
type
label
Constitutive phosphorylation o ...... quent overexpression in cancer
@ast
Constitutive phosphorylation o ...... quent overexpression in cancer
@en
Constitutive phosphorylation o ...... uent overexpression in cancer.
@nl
prefLabel
Constitutive phosphorylation o ...... quent overexpression in cancer
@ast
Constitutive phosphorylation o ...... quent overexpression in cancer
@en
Constitutive phosphorylation o ...... uent overexpression in cancer.
@nl
P2093
P2860
P50
P1433
P1476
Constitutive phosphorylation o ...... quent overexpression in cancer
@en
P2093
Hidehiko Kawai
Ikuko Ogawa
Masaaki Tatsuka
Takashi Takata
P2860
P356
10.1371/JOURNAL.PONE.0000944
P407
P577
2007-09-26T00:00:00Z