Fanconi anemia proteins stabilize replication forks. - Wikidata - awgldk - TriplyDB

Fanconi anemia proteins stabilize replication forks.

Fanconi anemia proteins stabilize replication forks.

http://www.wikidata.org/entity/Q33368942

about

Fanconi anemia complementation group A (FANCA) protein has intrinsic affinity for nucleic acids with preference for single-stranded forms Checkpoint signaling from a single DNA interstrand crosslink DNA double-strand break repair pathway choice and cancer FANCI protein binds to DNA and interacts with FANCD2 to recognize branched structures Cellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: mechanistic insights A reduction of licensed origins reveals strain-specific replication dynamics in mice Purification of FANCD2 sub-complexes.FANCJ helicase uniquely senses oxidative base damage in either strand of duplex DNA and is stimulated by replication protein A to unwind the damaged DNA substrate in a strand-specific manner.ATR activation and replication fork restart are defective in FANCM-deficient cells.Targeted inhibition of Replication Protein A reveals cytotoxic activity, synergy with chemotherapeutic DNA-damaging agents, and insight into cellular function.A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression.Fanconi anemia signaling and Mus81 cooperate to safeguard development and crosslink repair Radiosensitization of mammary carcinoma cells by telomere homolog oligonucleotide pretreatment.The Fanconi anemia pathway and ICL repair: implications for cancer therapy.Damage-dependent regulation of MUS81-EME1 by Fanconi anemia complementation group A protein.Human Fanconi anemia complementation group a protein stimulates the 5' flap endonuclease activity of FEN1.DNA repair: from genome maintenance to biomarker and therapeutic target.Replication Protein A (RPA) deficiency activates the Fanconi anemia DNA repair pathway.Fanconi anemia proteins FANCD2 and FANCI exhibit different DNA damage responses during S-phase The Interferon Consensus Sequence Binding Protein (Icsbp/Irf8) Is Required for Termination of Emergency Granulopoiesis.A novel interplay between the Fanconi anemia core complex and ATR-ATRIP kinase during DNA cross-link repair.Increased Fanconi C expression contributes to the emergency granulopoiesis response Recent insights into the molecular mechanisms involved in aging and the malignant transformation of adult stem/progenitor cells and their therapeutic implications.Cell-free Xenopus egg extracts for studying DNA damage response pathways.Cell resistance to the Cytolethal Distending Toxin involves an association of DNA repair mechanisms.FANCJ helicase operates in the Fanconi Anemia DNA repair pathway and the response to replicational stress.FANCD2 functions as a critical factor downstream of MiTF to maintain the proliferation and survival of melanoma cells Maintenance of genome stability by Fanconi anemia proteins.RAD51C: a novel cancer susceptibility gene is linked to Fanconi anemia and breast cancer.Stress and DNA repair biology of the Fanconi anemia pathway The human oncoprotein and chromatin architectural factor DEK counteracts DNA replication stress.Reduced FANCD2 influences spontaneous SCE and RAD51 foci formation in uveal melanoma and Fanconi anaemia.Rad18 E3 ubiquitin ligase activity mediates Fanconi anemia pathway activation and cell survival following DNA Topoisomerase 1 inhibition.Fanconi anemia: a paradigm of discovering molecular pathways from patients.Hypoxic stress facilitates acute activation and chronic downregulation of fanconi anemia proteins.Monoketone analogs of curcumin, a new class of Fanconi anemia pathway inhibitors.Fanconi anemia proteins and endogenous stresses.Stat3 and CCAAT enhancer-binding protein β (C/ebpβ) activate Fanconi C gene transcription during emergency granulopoiesis.TP53 Haploinsufficiency Rescues Emergency Granulopoiesis in FANCC-/- Mice.

P2860

Q24631719-2106DEB5-0E74-4F68-9A4E-14F8F176C509 Q24657928-A01420C8-8E78-42FE-BF0F-6F74A518431D Q26996175-A5F9DC89-D63E-4EDA-9E82-C734DF03C0F8 Q28250124-0043A0D1-3247-43C7-9B5E-6712A2FCC5CC Q28252640-DD2215A8-2AE3-4EBB-894A-F9801177C74D Q28507067-E8A47A00-FE91-4EAC-87F6-846238983009 Q30450792-2F971D42-8E33-4B09-A64C-4259ECABFB2C Q30863349-F91EA143-228D-4A42-8181-C6670EE3EF2C Q33522555-6F66A21C-01B5-4145-9784-1B9E25A363A1 Q33556289-14B50AAD-A8CE-4EF7-85B6-D584C149D42E Q33635514-AF3434F0-B33D-40C5-BE78-1907C68C870E Q34115459-7CF70C31-1B10-4165-B105-3114A4F42EE3 Q34989021-521AB171-F725-44B6-BD18-51F35E1886F5 Q35024542-D992062D-75F6-47C3-AFD5-C34D00351294 Q35028557-CDC00812-E27F-43A9-A3E2-A8DF57DC5032 Q35070427-69B63AE2-A94A-41D8-B9FD-7038D56F24D8 Q35555880-7A97AB7D-791D-41F3-8A71-055D3687B6DD Q36072502-A1D7CDEC-0261-441A-A20B-D015312DDA92 Q36280755-5BA4D608-50F5-4757-81D9-D7DAEF63E28A Q36594710-B9FDCAFD-FAB4-4353-B78A-F9637F7F6A65 Q37080394-A0DF22AE-A588-4E34-95EC-7D31088BAEA4 Q37123923-95F268D7-9D7C-40CB-8419-AF0A9ACA7A2A Q37310063-1EDB19A5-8098-42A7-BDD0-4AD5B02B2DB5 Q37351727-67BE7156-7899-4ED6-979F-8649FE4B6EFA Q37360355-B10BDCA9-E460-4846-9DAB-03ADA824CBC3 Q37391123-D5EB4948-DD09-4C9E-940F-B714ABCA8E3A Q37402621-0AAC8030-75B7-4E78-961F-694A6F228D28 Q37658498-A50B618E-8B0D-48A4-949B-F0F595571463 Q37800769-F63FE83A-C375-42CA-94E5-499F9AE375CC Q38252562-BDEE8CDA-491A-4017-AC36-F9FDD00BC9A9 Q38944912-ADE143D9-63FC-4DD0-A05C-D9FF273740BE Q39210775-DDA2C3EF-7E54-48A0-8AB5-132F6D650408 Q39561547-985EF38F-19B9-485F-A6D4-96665C30C887 Q41809959-E1D1F7CD-C56F-40C0-B4A4-A5248FE33AFB Q42024219-E14C1EE6-9CBD-4687-BCE7-665E2D82025B Q42094650-C30C435F-F5FE-42E9-8EB2-6804CEEFD04D Q42548726-22912ED7-5D9D-4E9C-AE76-16D10D03F605 Q49571810-7813C07A-DB5D-43CC-B8AE-0D6AB84D6968 Q50088140-87CE7E4A-7230-48FE-AAEF-0FB2B6577F91

P2860

Fanconi anemia proteins stabilize replication forks.

http://www.wikidata.org/entity/Q33368942

description

2008 nî lūn-bûn

@nan

2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

Fanconi anemia proteins stabilize replication forks.

@ast

Fanconi anemia proteins stabilize replication forks.

@en

type

label

Fanconi anemia proteins stabilize replication forks.

@ast

Fanconi anemia proteins stabilize replication forks.

@en

prefLabel

Fanconi anemia proteins stabilize replication forks.

@ast

Fanconi anemia proteins stabilize replication forks.

@en

P1433

Q33368942-6B943843-72C6-403F-9ABF-09802A6B235E

P1476

Q33368942-D851FF17-0066-46F1-849E-46F5318F3A30

P2093

Q33368942-2FC51B72-5857-4D05-8E46-72A1DF94978D

Q33368942-A5578C03-A49F-45FB-9F98-C932D79C71F2

Q33368942-A88303B2-4799-47BA-A4F6-D4803CDC893E

Q33368942-B5BF12AE-7163-447A-A513-AC8D24DDB862

P2860

Q33368942-01EC76E6-E8A7-4092-9413-AEFC01A216AA

Q33368942-1691805D-981E-4002-864D-567F0F6F4D44

Q33368942-2F1D547A-B3EE-4AD3-9EE6-AEA95D3193D9

Q33368942-34BC9966-A358-4162-ADA4-384839FA3BCC

Q33368942-356A1FDB-42E6-4ECF-B407-678E64FAA5F7

Q33368942-3738D48A-F058-45ED-BF46-E1E57FFDD9B9

Q33368942-3921453B-E790-4815-8309-D1F5E1C0A16E

Q33368942-39B83109-4615-483D-98C7-B3074511F600

Q33368942-3AAEF386-1DA5-4543-8C51-C8E61584828D

Q33368942-3B7D2547-D6FC-4824-95D4-C5C4CE5E39C1

P304

Q33368942-C7755886-CF0D-4AAF-88BB-220544797E91

P31

Q33368942-E858EB2F-C187-40A5-B830-D2024BA9891F

P356

Q33368942-76C0C29D-75D3-49FB-B9EE-76A639BE8440

P433

Q33368942-E7EB8E2E-7176-43D1-8B43-F33C66ACDA84

P478

Q33368942-CF4F8DA7-1798-41E1-A74A-F0E64D135565

P577

Q33368942-F74A2D9E-AB50-493D-9F96-D2AF68D6F4CA

P5875

Q33368942-397AD0CB-387F-4B54-B653-8729B98ADDEA

P698

Q33368942-0325C4F6-22BB-42F8-A306-C4BDFDE43AD8

P932

Q33368942-29DFB8CD-C1A7-4CDE-97A2-707CD535B094

P356

J.DNAREP.2008.08.005

P1433

P1476

Fanconi anemia proteins stabilize replication forks.

@en

P2093

Jean Gautier

http://www.w3.org/2001/XMLSchema#string

Lily Chien Wang

http://www.w3.org/2001/XMLSchema#string

Maureen Elizabeth Hoatlin

http://www.w3.org/2001/XMLSchema#string

Stacie Stone

http://www.w3.org/2001/XMLSchema#string

P2860

BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function

UBE2T, the Fanconi anemia core complex, and FANCD2 are recruited independently to chromatin: a basis for the regulation of FANCD2 monoubiquitination.

FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway

FANCI is a second monoubiquitinated member of the Fanconi anemia pathway

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways

Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin

A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M

Chk1-mediated phosphorylation of FANCE is required for the Fanconi anemia/BRCA pathway

Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair

P304

1973-1981

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.DNAREP.2008.08.005

http://www.w3.org/2001/XMLSchema#string

P433

12

http://www.w3.org/2001/XMLSchema#string

P478

7

http://www.w3.org/2001/XMLSchema#string

P577

2008-09-25T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

23253108

http://www.w3.org/2001/XMLSchema#string

P698

18786657

http://www.w3.org/2001/XMLSchema#string

P932

2596863

http://www.w3.org/2001/XMLSchema#string