Novel acridine-based compounds that exhibit an anti-pancreatic cancer activity are catalytic inhibitors of human topoisomerase II.

Novel acridine-based compounds that exhibit an anti-pancreatic cancer activity are catalytic inhibitors of human topoisomerase II.

Item
http://www.wikidata.org/entity/Q33391858
Structure and stability of human telomeric G-quadruplex with preclinical 9-amino acridinesOn the role of topoisomerase I in mediating the cytotoxicity of 9-aminoacridine-based anticancer agentsSynthesis of acridines by the [4 + 2] annulation of arynes and 2-aminoaryl ketonesEfficacy of substituted 9-aminoacridine derivatives in small cell lung cancer.Synthesis and biological evaluation of acridine derivatives as antimalarial agents.Novel acridine-based agents with topoisomerase II inhibitor activity suppress mesothelioma cell proliferation and induce apoptosis.Quinacrine has anticancer activity in breast cancer cells through inhibition of topoisomerase activity.Riccardin D, a novel macrocyclic bisbibenzyl, induces apoptosis of human leukemia cells by targeting DNA topoisomerase II.9-Amino acridine pharmacokinetics, brain distribution, and in vitro/in vivo efficacy against malignant glioma.Assessment of DNA-binding affinity of cholinesterase reactivators and electrophoretic determination of their effect on topoisomerase I and II activity.
P2860

Novel acridine-based compounds that exhibit an anti-pancreatic cancer activity are catalytic inhibitors of human topoisomerase II.

Item
http://www.wikidata.org/entity/Q33391858
description
2008 nî lūn-bûn
@nan
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
name
Novel acridine-based compounds ...... ors of human topoisomerase II.
@ast
Novel acridine-based compounds ...... ors of human topoisomerase II.
@en
type
label
Novel acridine-based compounds ...... ors of human topoisomerase II.
@ast
Novel acridine-based compounds ...... ors of human topoisomerase II.
@en
prefLabel
Novel acridine-based compounds ...... ors of human topoisomerase II.
@ast
Novel acridine-based compounds ...... ors of human topoisomerase II.
@en
P1433
P1476
P2093
P2860
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P31
P356
P407
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Novel acridine-based compounds ...... ors of human topoisomerase II.
@en
P2093
P2860
P304
P31
P356
10.1016/J.EJPHAR.2008.11.044
P407
P433
P478
P577
P5875
P698
P932