Quinacrine has anticancer activity in breast cancer cells through inhibition of topoisomerase activity.
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Pentacyclic Triterpenoids Inhibit IKKβ Mediated Activation of NF-κB Pathway: In Silico and In Vitro EvidencesRepurposing the anti-malarial drug, quinacrine: new anti-colitis propertiesDrug screen in patient cells suggests quinacrine to be repositioned for treatment of acute myeloid leukemia.Experimental validation of FINDSITE(comb) virtual ligand screening results for eight proteins yields novel nanomolar and micromolar binders.Identification of inhibitors of ovarian cancer stem-like cells by high-throughput screening.Quinacrine promotes autophagic cell death and chemosensitivity in ovarian cancer and attenuates tumor growth.Nanoquinacrine induced apoptosis in cervical cancer stem cells through the inhibition of hedgehog-GLI1 cascade: Role of GLI-15-Fluorouracil mediated anti-cancer activity in colon cancer cells is through the induction of Adenomatous Polyposis Coli: Implication of the long-patch base excision repair pathway.The DNA virus white spot syndrome virus uses an internal ribosome entry site for translation of the highly expressed nonstructural protein ICP35.9-AAA inhibits growth and induces apoptosis in human melanoma A375 and rat prostate adenocarcinoma AT-2 and Mat-LyLu cell lines but does not affect the growth and viability of normal fibroblastsQuinacrine induces apoptosis in cancer cells by forming a functional bridge between TRAIL-DR5 complex and modulating the mitochondrial intrinsic cascade.Etoposide and doxorubicin enhance the sensitivity of triple negative breast cancers through modulation of TRAIL-DR5 axis.A Quinacrine Analogue Selective Against Gastric Cancer Cells: Insight from Biochemical and Biophysical Studies.Chitosan-Dextran sulfate coated doxorubicin loaded PLGA-PVA-nanoparticles caused apoptosis in doxorubicin resistance breast cancer cells through induction of DNA damage.Characterization of Anticancer Principles of Celosia argentea (Amaranthaceae)NECTIN-4 increased the 5-FU resistance in colon cancer cells by inducing the PI3K-AKT cascade.L-carvone induces p53, caspase 3 mediated apoptosis and inhibits the migration of breast cancer cell lines.1,3-Bis(2-chloroethyl)-1-nitrosourea enhances the inhibitory effect of resveratrol on 5-fluorouracil sensitive/resistant colon cancer cells.Structural elaboration of a natural product: identification of 3,3'-diindolylmethane aminophosphonate and urea derivatives as potent anticancer agents.Silver-based nanoparticles induce apoptosis in human colon cancer cells mediated through p53.Lycopene synergistically enhances quinacrine action to inhibit Wnt-TCF signaling in breast cancer cells through APC.Amsacrine-induced apoptosis of human leukemia U937 cells is mediated by the inhibition of AKT- and ERK-induced stabilization of MCL1.Cytosporone B, an inhibitor of the type III secretion system of Salmonella enterica serovar Typhimurium.Inhibition of Kir4.1 potassium channels by quinacrine.Quinacrine Inhibits ICAM-1 Transcription by Blocking DNA Binding of the NF-κB Subunit p65 and Sensitizes Human Lung Adenocarcinoma A549 Cells to TNF-α and the Fas Ligand.Quinacrine upregulates p21/p27 independent of p53 through autophagy-mediated downregulation of p62-Skp2 axis in ovarian cancer.TRAIL enhances quinacrine-mediated apoptosis in breast cancer cells through induction of autophagy via modulation of p21 and DR5 interactions.
P2860
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P2860
Quinacrine has anticancer activity in breast cancer cells through inhibition of topoisomerase activity.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Quinacrine has anticancer acti ...... ion of topoisomerase activity.
@en
Quinacrine has anticancer acti ...... ion of topoisomerase activity.
@nl
type
label
Quinacrine has anticancer acti ...... ion of topoisomerase activity.
@en
Quinacrine has anticancer acti ...... ion of topoisomerase activity.
@nl
prefLabel
Quinacrine has anticancer acti ...... ion of topoisomerase activity.
@en
Quinacrine has anticancer acti ...... ion of topoisomerase activity.
@nl
P2093
P2860
P356
P1476
Quinacrine has anticancer acti ...... ion of topoisomerase activity.
@en
P2093
Chanakya Nath Kundu
Purusottam Mohapatra
Suchitra Mohanty
Sushil Kumar Sahu
Tathagata Choudhuri
P2860
P304
P356
10.1002/IJC.26158
P577
2011-08-16T00:00:00Z