Quantitative-qualitative data acquisition using a benchtop Orbitrap mass spectrometer.
about
Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometerExploring the utility of high-resolution MS with post-acquisition data mining for simultaneous exogenous and endogenous metabolite profiling.Data acquisition and data mining techniques for metabolite identification using LC coupled to high-resolution MS.Design Study of an Atmospheric Pressure Photoionization Interface for GC-MS.The development and validation of a method using high-resolution mass spectrometry (HRMS) for the qualitative detection of antiretroviral agents in human bloodHigh-resolution chromatography/time-of-flight MSE with in silico data mining is an information-rich approach to reactive metabolite screening.Current use of high-resolution mass spectrometry in drug screening relevant to clinical and forensic toxicology and doping control.Qualitative-(semi)quantitative data acquisition of artemisinin and its metabolites in rat plasma using an LTQ/Orbitrap mass spectrometer.Simultaneous screening of glutathione and cyanide adducts using precursor ion and neutral loss scans-dependent product ion spectral acquisition and data mining tools.HRMS: current usage, future directions and the promise of integration with unified data streams suited to post-acquisition mining.Integrated quantitative and qualitative workflow for in vivo bioanalytical support in drug discovery using hybrid Q-TOF-MS.Mass spectrometry-based proteomics using Q Exactive, a high-performance benchtop quadrupole Orbitrap mass spectrometer.The science of laboratory and project management in regulated bioanalysis.Modify on the fly: triple quad to high resolution in support of a dermal clinical study requiring an ultra low LLOQ.Comparison of high-resolution and tandem mass spectrometry for the analysis of nerve agent metabolites in urine.Recent development in high-throughput bioanalytical support for in vitro ADMET profiling.Advances in mass spectrometry applied to pharmaceutical metabolomics.Approaches for the rapid identification of drug metabolites in early clinical studies.Drug metabolite profiling and identification by high-resolution mass spectrometry.Screening of plant toxins in food, feed and botanicals using full-scan high-resolution (Orbitrap) mass spectrometry.Absolute quantitation of protein therapeutics in biological matrices by enzymatic digestion and LC-MS.Metabolite identification and quantitation in LC-MS/MS-based metabolomics.SPE-MS analysis of absorption, distribution, metabolism and excretion assays: a tool to increase throughput and steamline workflow.Metabolite structure analysis by high-resolution MS: supporting drug-development studies.High resolution mass spectrometry based techniques at the crossroads of metabolic pathways.Introduction of a routine quan/qual approach into research DMPK: experiences and evolving strategies.Challenges of analyzing different classes of metabolites by a single analytical method.Multi-drug and metabolite quantification in postmortem blood by liquid chromatography-high-resolution mass spectrometry: comparison with nominal mass technology.Insecticide ADME for support of early-phase discovery: combining classical and modern techniques.Development, optimization and implementation of a centralized metabolic soft spot assay.Recent developments in software tools for high-throughput in vitro ADME support with high-resolution MS.An assessment of endocrine activity in Australian rivers using chemical and in vitro analyses.An efficient liquid chromatography-high resolution mass spectrometry approach for the optimization of the metabolic stability of therapeutic peptides.Future applications of high-resolution MS to meet the demands for pain management drug testing.High-resolution MS in regulated bioanalysis: where are we now and where do we go from here?Applications of high-resolution MS in bioanalysis.The future key role of LC-high-resolution-MS analyses in clinical laboratories: a focus on quantification.HRMS using a Q-Exactive series mass spectrometer for regulated quantitative bioanalysis: how, when, and why to implement.Characterization of endocrine disruptors from a complex matrix using estrogen receptor affinity columns and high performance liquid chromatography-high resolution mass spectrometry.Simultaneous bioanalysis of a phosphate prodrug and its parent compound using a multiplexed LC-MS method.
P2860
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P2860
Quantitative-qualitative data acquisition using a benchtop Orbitrap mass spectrometer.
description
2009 nî lūn-bûn
@nan
2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Quantitative-qualitative data acquisition using a benchtop Orbitrap mass spectrometer.
@ast
Quantitative-qualitative data acquisition using a benchtop Orbitrap mass spectrometer.
@en
type
label
Quantitative-qualitative data acquisition using a benchtop Orbitrap mass spectrometer.
@ast
Quantitative-qualitative data acquisition using a benchtop Orbitrap mass spectrometer.
@en
prefLabel
Quantitative-qualitative data acquisition using a benchtop Orbitrap mass spectrometer.
@ast
Quantitative-qualitative data acquisition using a benchtop Orbitrap mass spectrometer.
@en
P2093
P2860
P1476
Quantitative-qualitative data acquisition using a benchtop Orbitrap mass spectrometer.
@en
P2093
Helmut Muenster
Lester Taylor
Markus Kellmann
Robert Papp
P2860
P2888
P304
P356
10.1016/J.JASMS.2009.03.002
P577
2009-03-06T00:00:00Z
P5875
P6179
1023355805