A high-capacity LC/MS system for the bioanalysis of samples generated from plate-based metabolic screening.
about
Predicting in vivo drug interactions from in vitro drug discovery data.Application of parallel liquid chromatography/mass spectrometry for high throughput microsomal stability screening of compound libraries.Recent advances in pharmacokinetic extrapolation from preclinical data to humans.Generic serial and parallel on-line direct-injection using turbulent flow liquid chromatography/tandem mass spectrometry.Quantitative-qualitative data acquisition using a benchtop Orbitrap mass spectrometer.Particle discriminator interface for nanoflow ESI-MS.The development and assessment of high-throughput mass spectrometry-based methods for the quantification of a nanoparticle drug delivery agent in cellular lysate.Minimising the potential for metabolic activation in drug discovery.Spirocyclic chromanes exhibit antiplasmodial activities and inhibit all intraerythrocytic life cycle stages.Recent development in high-throughput bioanalytical support for in vitro ADMET profiling.4-Nitro styrylquinoline is an antimalarial inhibiting multiple stages of Plasmodium falciparum asexual life cycle.Application of a rapid and integrated analysis system (RIAS) as a high-throughput processing tool for in vitro ADME samples by liquid chromatography/tandem mass spectrometry.Recent development in software and automation tools for high-throughput discovery bioanalysis.SPE-MS analysis of absorption, distribution, metabolism and excretion assays: a tool to increase throughput and steamline workflow.A Comparison of LC-MS/MS and a Fully Integrated Autosampler/Solid-Phase Extraction System for the Analysis of Protein Binding Samples.A high-speed liquid chromatography/tandem mass spectrometry platform using multiplexed multiple-injection chromatography controlled by single software and its application in discovery ADME screening.Utility of multivariate analysis in support of in vitro metabolite identification studies: retrospective analysis using the antidepressant drug nefazodone.High-speed liquid chromatography/tandem mass spectrometry using a monolithic column for high-throughput bioanalysis.A preliminary study on the feasibility of an automated blood-sampling system in conjunction with liquid chromatography/mass spectrometry.A rapid, automated approach to optimisation of multiple reaction monitoring conditions for quantitative bioanalytical mass spectrometry.Development of a high-speed, multiplexed sample-delivery instrument for LC-MS/MS bioanalysis.Optimization of a higher throughput microsomal stability screening assay for profiling drug discovery candidates.Development of a high-performance, enterprise-level, multimode LC-MS/MS autosampler for drug discovery.
P2860
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P2860
A high-capacity LC/MS system for the bioanalysis of samples generated from plate-based metabolic screening.
description
2001 nî lūn-bûn
@nan
2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
A high-capacity LC/MS system f ...... ate-based metabolic screening.
@ast
A high-capacity LC/MS system f ...... ate-based metabolic screening.
@en
A high-capacity LC/MS system f ...... ate-based metabolic screening.
@nl
type
label
A high-capacity LC/MS system f ...... ate-based metabolic screening.
@ast
A high-capacity LC/MS system f ...... ate-based metabolic screening.
@en
A high-capacity LC/MS system f ...... ate-based metabolic screening.
@nl
prefLabel
A high-capacity LC/MS system f ...... ate-based metabolic screening.
@ast
A high-capacity LC/MS system f ...... ate-based metabolic screening.
@en
A high-capacity LC/MS system f ...... ate-based metabolic screening.
@nl
P2093
P356
P1433
P1476
A high-capacity LC/MS system f ...... ate-based metabolic screening.
@en
P2093
Duchoslav E
Janiszewski JS
P304
P356
10.1021/AC0013251
P407
P577
2001-04-01T00:00:00Z