Discovery of a novel HCV helicase inhibitor by a de novo drug design approach.

Discovery of a novel HCV helicase inhibitor by a de novo drug design approach.

Item
http://www.wikidata.org/entity/Q33438777
Inhibition of RNA Helicases of ssRNA(+) Virus Belonging to Flaviviridae, Coronaviridae and Picornaviridae FamiliesComputational methods in drug discoveryFragment-based modelling of single stranded RNA bound to RNA recognition motif containing proteins.Unique helicase determinants in the essential conjugative TraI factor from Salmonella enterica serovar Typhimurium plasmid pCU1.In silico fragment-based drug design using a PASS approach.Ebselen inhibits hepatitis C virus NS3 helicase binding to nucleic acid and prevents viral replicationDiscovering new medicines targeting helicases: challenges and recent progress.Binding Site Identification and Flexible Docking of Single Stranded RNA to Proteins Using a Fragment-Based Approach.A holistic evolutionary and structural study of flaviviridae provides insights into the function and inhibition of HCV helicase.Fragment informatics and computational fragment-based drug design: an overview and update.De novo design: balancing novelty and confined chemical space.Designing the molecular future.Protein signatures using electrostatic molecular surfaces in harmonic space.Molecular modeling and pharmacophore elucidation study of the Classical Swine Fever virus helicase as a promising pharmacological target.Customizable de novo design strategies for DOCK: Application to HIVgp41 and other therapeutic targets.HCV genetics and genotypes dictate future antiviral strategies.
P2860

Discovery of a novel HCV helicase inhibitor by a de novo drug design approach.

Item
http://www.wikidata.org/entity/Q33438777
description
2009 nî lūn-bûn
@nan
2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Discovery of a novel HCV helicase inhibitor by a de novo drug design approach.
@ast
Discovery of a novel HCV helicase inhibitor by a de novo drug design approach.
@en
type
label
Discovery of a novel HCV helicase inhibitor by a de novo drug design approach.
@ast
Discovery of a novel HCV helicase inhibitor by a de novo drug design approach.
@en
prefLabel
Discovery of a novel HCV helicase inhibitor by a de novo drug design approach.
@ast
Discovery of a novel HCV helicase inhibitor by a de novo drug design approach.
@en
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P356
P1433
P1476
Discovery of a novel HCV helicase inhibitor by a de novo drug design approach.
@en
P2093
P304
P31
P356
10.1016/J.BMCL.2009.04.074
P407
P433
P478
P50
P577
P5875
P698