20-Hydroxycholecalciferol, product of vitamin D3 hydroxylation by P450scc, decreases NF-kappaB activity by increasing IkappaB alpha levels in human keratinocytes.
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IKKε knockout prevents high fat diet induced arterial atherosclerosis and NF-κB signaling in miceProducts of vitamin D3 or 7-dehydrocholesterol metabolism by cytochrome P450scc show anti-leukemia effects, having low or absent calcemic activity.Novel vitamin D analogs as potential therapeutics: metabolism, toxicity profiling, and antiproliferative activity.Purified mouse CYP27B1 can hydroxylate 20,23-dihydroxyvitamin D3, producing 1alpha,20,23-trihydroxyvitamin D3, which has altered biological activitySensing the environment: regulation of local and global homeostasis by the skin's neuroendocrine system.Metabolism of 20-hydroxyvitamin D3 by mouse liver microsomesKey role of CRF in the skin stress response system.CYP24A1 expression inversely correlates with melanoma progression: clinic-pathological studies.Neuroendocrinology of the skin: An overview and selective analysis20-Hydroxyvitamin D2 is a noncalcemic analog of vitamin D with potent antiproliferative and prodifferentiation activities in normal and malignant cells.Pseudomonas-derived ceramidase induces production of inflammatory mediators from human keratinocytes via sphingosine-1-phosphate.Production of 22-hydroxy metabolites of vitamin d3 by cytochrome p450scc (CYP11A1) and analysis of their biological activities on skin cellsMetabolism of 20-hydroxyvitamin D3 and 20,23-dihydroxyvitamin D3 by rat and human CYP24A1Novel interactive partners of neuroligin 3: new aspects for pathogenesis of autism.Antitumor effects of vitamin D analogs on hamster and mouse melanoma cell lines in relation to melanin pigmentation.Vitamin D prevents hypoxia/reoxygenation-induced blood-brain barrier disruption via vitamin D receptor-mediated NF-kB signaling pathways.A Proposed Molecular Mechanism of High-Dose Vitamin D3 Supplementation in Prevention and Treatment of Preeclampsia.Detection of novel CYP11A1-derived secosteroids in the human epidermis and serum and pig adrenal gland.In vivo evidence for a novel pathway of vitamin D₃ metabolism initiated by P450scc and modified by CYP27B1.Chemical Synthesis and Biological Activities of 20S,24S/R-Dihydroxyvitamin D3 Epimers and Their 1α-Hydroxyl Derivatives.On the role of skin in the regulation of local and systemic steroidogenic activities.Total synthesis of biologically active 20S-hydroxyvitamin D3.Effect of Nordic Walking training on iron metabolism in elderly women.Cytochrome P450scc-dependent metabolism of 7-dehydrocholesterol in placenta and epidermal keratinocytesNovel activities of CYP11A1 and their potential physiological significance.Hydroxylation of 20-hydroxyvitamin D3 by human CYP3A4.Hydroxylation of CYP11A1-derived products of vitamin D3 metabolism by human and mouse CYP27B1.The Vitamin D Receptor, Inflammatory Bowel Diseases, and Colon CancerCytochromes p450 and skin cancer: role of local endocrine pathways.Endocannabinoid crosstalk between placenta and maternal fat in a baboon model (Papio spp.) of obesityNovel vitamin D compounds and skin cancer prevention.Novel vitamin D photoproducts and their precursors in the skin.Noncalcemic 20-hydroxyvitamin D3 inhibits human melanoma growth in in vitro and in vivo modelsDesign, Synthesis and Biological Activities of Novel Gemini 20S-Hydroxyvitamin D3 Analogs.In vivo production of novel vitamin D2 hydroxy-derivatives by human placentas, epidermal keratinocytes, Caco-2 colon cells and the adrenal gland.The role of CYP11A1 in the production of vitamin D metabolites and their role in the regulation of epidermal functions.Effect of 1,25(OH)2 D3 and 20(OH)D3 on interleukin-1β-stimulated interleukin-6 and -8 production by human gingival fibroblasts.Novel non-calcemic secosteroids that are produced by human epidermal keratinocytes protect against solar radiation.On the role of classical and novel forms of vitamin D in melanoma progression and management.Melatonin and its metabolites ameliorate ultraviolet B-induced damage in human epidermal keratinocytes.
P2860
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P2860
20-Hydroxycholecalciferol, product of vitamin D3 hydroxylation by P450scc, decreases NF-kappaB activity by increasing IkappaB alpha levels in human keratinocytes.
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
20-Hydroxycholecalciferol, pro ...... levels in human keratinocytes.
@ast
20-Hydroxycholecalciferol, pro ...... levels in human keratinocytes.
@en
type
label
20-Hydroxycholecalciferol, pro ...... levels in human keratinocytes.
@ast
20-Hydroxycholecalciferol, pro ...... levels in human keratinocytes.
@en
prefLabel
20-Hydroxycholecalciferol, pro ...... levels in human keratinocytes.
@ast
20-Hydroxycholecalciferol, pro ...... levels in human keratinocytes.
@en
P2093
P2860
P50
P1433
P1476
20-Hydroxycholecalciferol, pro ...... levels in human keratinocytes.
@en
P2093
Damon A DeLeon
Minh N Nguyen
Zorica Janjetovic
P2860
P356
10.1371/JOURNAL.PONE.0005988
P407
P577
2009-06-19T00:00:00Z