Histological evaluation of AMPK signalling in primary breast cancer - Wikidata - awgldk - TriplyDB

Histological evaluation of AMPK signalling in primary breast cancer

Histological evaluation of AMPK signalling in primary breast cancer

http://www.wikidata.org/entity/Q33499119

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AMPK: opposing the metabolic changes in both tumour cells and inflammatory cells?Dissecting the Dual Role of AMPK in Cancer: From Experimental to Human Studies Aminoimidazole carboxamide ribonucleotide (AICAR) inhibits the growth of retinoblastoma in vivo by decreasing angiogenesis and inducing apoptosis Inhibition of the LKB1-AMPK pathway by the Epstein-Barr virus-encoded LMP1 promotes proliferation and transformation of human nasopharyngeal epithelial cells Metformin effects on biochemical recurrence and metabolic signaling in the prostate.Metformin-treated cancer cells modulate macrophage polarization through AMPK-NF-κB signaling.The RNA helicase/transcriptional co-regulator, p68 (DDX5), stimulates expression of oncogenic protein kinase, Polo-like kinase-1 (PLK1), and is associated with elevated PLK1 levels in human breast cancers AMPK as a metabolic tumor suppressor: control of metabolism and cell growth.Prognostic significance of AMPK activation in advanced stage colorectal cancer treated with chemotherapy plus bevacizumab.The effect of 5-aminoimidazole-4-carboxamide-ribonucleoside was mediated by p38 mitogen activated protein kinase signaling pathway in FRO thyroid cancer cells.Prognostic significance of AMP-activated protein kinase expression and modifying effect of MAPK3/1 in colorectal cancer.Chromosome 9p deletion in clear cell renal cell carcinoma predicts recurrence and survival following surgery.A novel dysregulated pathway-identification analysis based on global influence of within-pathway effects and crosstalk between pathways.AMPK-activated protein kinase activation by Impatiens balsamina L. is related to apoptosis in HSC-2 human oral cancer cells Involvement of metformin and AMPK in the radioresponse and prognosis of luminal versus basal-like breast cancer treated with radiotherapy Association between phosphorylated AMP-activated protein kinase and acetyl-CoA carboxylase expression and outcome in patients with squamous cell carcinoma of the head and neck.The glycolytic shift in fumarate-hydratase-deficient kidney cancer lowers AMPK levels, increases anabolic propensities and lowers cellular iron levels.Changes in insulin receptor signaling underlie neoadjuvant metformin administration in breast cancer: a prospective window of opportunity neoadjuvant study.MAGE-A Cancer/Testis Antigens Inhibit MDM2 Ubiquitylation Function and Promote Increased Levels of MDM4 Metformin and the ATM DNA damage response (DDR): accelerating the onset of stress-induced senescence to boost protection against cancer Targeting AMPK for cancer prevention and treatment.AMP-activated kinase (AMPK) regulates activity of HER2 and EGFR in breast cancer.Molecular Pathways: Is AMPK a Friend or a Foe in Cancer?Immunohistochemical detection of Polo-like kinase-1 (PLK1) in primary breast cancer is associated with TP53 mutation and poor clinical outcom AMPK Inhibits the Stimulatory Effects of TGF-β on Smad2/3 Activity, Cell Migration, and Epithelial-to-Mesenchymal Transition.ATM and LKB1 dependent activation of AMPK sensitizes cancer cells to etoposide-induced apoptosis AMP-Activated Protein Kinase Signalling in Cancer and Cardiac Hypertrophy.AMPK is a negative regulator of the Warburg effect and suppresses tumor growth in vivo.LKB1/AMPK inhibits TGF-β1 production and the TGF-β signaling pathway in breast cancer cells.AMP-Activated Protein Kinase α 2 Isoform Suppression in Primary Breast Cancer Alters AMPK Growth Control and Apoptotic Signaling.Potential applications for biguanides in oncology Group X secreted phospholipase A(2) induces lipid droplet formation and prolongs breast cancer cell survival.mir-101-3p is a key regulator of tumor metabolism in triple negative breast cancer targeting AMPK.AMPKα Is Suppressed in Bladder Cancer through Macrophage-Mediated Mechanisms.Gene co-expression network analysis reveals common system-level properties of prognostic genes across cancer types.AMP-activated protein kinase and energy balance in breast cancer.Perspectives of the AMP-activated kinase (AMPK) signalling pathway in thyroid cancer.Metabolic alterations in cancer cells and therapeutic implications.Targeting the liver kinase B1/AMP-activated protein kinase pathway as a therapeutic strategy for hematological malignancies.Role of AMP-activated protein kinase in cancer therapy.

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Histological evaluation of AMPK signalling in primary breast cancer

http://www.wikidata.org/entity/Q33499119

description

2009 nî lūn-bûn

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2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Histological evaluation of AMPK signalling in primary breast cancer

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Histological evaluation of AMPK signalling in primary breast cancer

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type

label

Histological evaluation of AMPK signalling in primary breast cancer

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Histological evaluation of AMPK signalling in primary breast cancer

@en

prefLabel

Histological evaluation of AMPK signalling in primary breast cancer

@ast

Histological evaluation of AMPK signalling in primary breast cancer

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Histological evaluation of AMPK signalling in primary breast cancer

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Alastair M Thompson

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David Kellock

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George Thomson

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Katherine E Robertson

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Lee B Jordan

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Lee Baker

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Sirwan M Hadad

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Stewart Fleming

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Susan E Bray

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P2860

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

The Hallmarks of Cancer

Role of AMP-activated protein kinase in mechanism of metformin action

The subcellular localization of acetyl-CoA carboxylase 2

Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia

Identification of the sucrose non-fermenting related kinase SNRK, as a novel LKB1 substrate

LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1

AMPK phosphorylation of raptor mediates a metabolic checkpoint

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

TSC2 mediates cellular energy response to control cell growth and survival

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1471-2407-9-307

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10.1186/1471-2407-9-307

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9

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Philip R Quinlan

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19723334

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