Identification of a small molecule inhibitor of the human DNA repair enzyme polynucleotide kinase/phosphatase.
about
DNA repair targeted therapy: The past or future of cancer treatment?Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substratesRole of polynucleotide kinase/phosphatase in mitochondrial DNA repairMechanism of action of an imidopiperidine inhibitor of human polynucleotide kinase/phosphatase.Comprehensive survey of chemical libraries for drug discovery and chemical biology: 2009.Structural and functional characterization of the PNKP-XRCC4-LigIV DNA repair complexTargeting DNA repair pathways for cancer treatment: what's new?Tidying up loose ends: the role of polynucleotide kinase/phosphatase in DNA strand break repair.Ataxin-3, DNA damage repair, and SCA3 cerebellar degeneration: on the path to parsimony?Why high cholesterol levels help hematological malignancies: role of nuclear lipid microdomains.Synthetic lethal targeting of PTEN-deficient cancer cells using selective disruption of polynucleotide kinase/phosphataseHuman HAD phosphatases: structure, mechanism, and roles in health and disease.Detection and repair of ionizing radiation-induced DNA double strand breaks: new developments in nonhomologous end joining.DNA end-processing enzyme polynucleotide kinase as a potential target in the treatment of cancer.Characterization of DNA Substrate Binding to the Phosphatase Domain of the DNA Repair Enzyme Polynucleotide Kinase/PhosphataseTargeting DNA repair with PNKP inhibition sensitizes radioresistant prostate cancer cells to high LET radiation.In vivo phosphoproteomics reveals kinase activity profiles that predict treatment outcome in triple-negative breast cancer
P2860
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P2860
Identification of a small molecule inhibitor of the human DNA repair enzyme polynucleotide kinase/phosphatase.
description
2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
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2009年の論文
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2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年學術文章
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name
Identification of a small mole ...... nucleotide kinase/phosphatase.
@ast
Identification of a small mole ...... nucleotide kinase/phosphatase.
@en
type
label
Identification of a small mole ...... nucleotide kinase/phosphatase.
@ast
Identification of a small mole ...... nucleotide kinase/phosphatase.
@en
prefLabel
Identification of a small mole ...... nucleotide kinase/phosphatase.
@ast
Identification of a small mole ...... nucleotide kinase/phosphatase.
@en
P2093
P1433
P1476
Identification of a small mole ...... nucleotide kinase/phosphatase.
@en
P2093
Aghdass Rasouli-Nia
Agnieszka Ulaczyk-Lesanko
Ashley Ahrens
Charles F B Holmes
Feridoun Karimi-Busheri
Frauke Rininsland
Gary K Freschauf
Jonathan M Koshy
Michael Weinfeld
Phuwadet Pasarj
P304
P356
10.1158/0008-5472.CAN-09-1805
P407
P577
2009-09-22T00:00:00Z