Sex determining region Y-Box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung. - Wikidata - awgldk - TriplyDB

Sex determining region Y-Box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung.

Sex determining region Y-Box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung.

http://www.wikidata.org/entity/Q33531781

about

Evidence that SOX2 overexpression is oncogenic in the lung The PRKCI and SOX2 oncogenes are coamplified and cooperate to activate Hedgehog signaling in lung squamous cell carcinoma Molecular biology of lung cancer: clinical implications Sox2 is an androgen receptor-repressed gene that promotes castration-resistant prostate cancer Molecular biomarkers of cancer stem/progenitor cells associated with progression, metastases, and treatment resistance of aggressive cancers The role of SOX2 in small cell lung cancer, lung adenocarcinoma and squamous cell carcinoma of the lung The impact of the Cancer Genome Atlas on lung cancer.Protein Kinase Cι Drives a NOTCH3-dependent Stem-like Phenotype in Mutant KRAS Lung Adenocarcinoma Divergent genomic and epigenomic landscapes of lung cancer subtypes underscore the selection of different oncogenic pathways during tumor development DNA copy number gains in malignant pleural mesothelioma Pulmonary adenocarcinoma: a renewed entity in 2011 EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer SOX2 expression is an early event in a murine model of EGFR mutant lung cancer and promotes proliferation of a subset of EGFR mutant lung adenocarcinoma cell lines.Activation of SOX2 expression by BRD4-NUT oncogenic fusion drives neoplastic transformation in NUT midline carcinoma.SOX2 is overexpressed in stem-like cells of human lung adenocarcinoma and augments the tumorigenicity.CAFET algorithm reveals Wnt/PCP signature in lung squamous cell carcinoma Matrix metalloproteinase-10 is required for lung cancer stem cell maintenance, tumor initiation and metastatic potential.True 3q chromosomal amplification in squamous cell lung carcinoma by FISH and aCGH molecular analysis: impact on targeted drugs High SOX2 levels predict better outcome in non-small cell lung carcinomas.The prognostic value of SOX2 expression in non-small cell lung cancer: a meta-analysis Sox2 activates cell proliferation and differentiation in the respiratory epithelium.Squamous Cell Carcinoma - Similarities and Differences among Anatomical Sites.The impact of phosphorylated AMP-activated protein kinase expression on lung cancer survival.Prognostic impact of insulin receptor expression on survival of patients with nonsmall cell lung cancer.Mutations in TP53 increase the risk of SOX2 copy number alterations and silencing of TP53 reduces SOX2 expression in non-small cell lung cancer.The role of SOX-2 on the survival of patients with non-small cell lung cancer An Integrated Molecular Analysis of Lung Adenocarcinomas Identifies Potential Therapeutic Targets among TTF1-Negative Tumors, Including DNA Repair Proteins and Nrf2.Prognostic implications of tumoral expression of insulin like growth factors 1 and 2 in patients with non-small-cell lung cancer.Activation of insulin-like growth factor 1 receptor in patients with non-small cell lung cancer.SOX2 and PI3K Cooperate to Induce and Stabilize a Squamous-Committed Stem Cell Injury State during Lung Squamous Cell Carcinoma Pathogenesis.Increased Sox2 copy number in lung squamous cell carcinomas.SOX2 and nestin expression in human melanoma: an immunohistochemical and experimental study.The chromosome 3q26 OncCassette: A multigenic driver of human cancer.The role of Sox genes in lung morphogenesis and cancer.CXCR2 expression in tumor cells is a poor prognostic factor and promotes invasion and metastasis in lung adenocarcinoma.SOX2 suppresses CDKN1A to sustain growth of lung squamous cell carcinoma.Sex determining region Y-box 2 (SOX2) amplification is an independent indicator of disease recurrence in sinonasal cancer.The pivotal role of IKKα in the development of spontaneous lung squamous cell carcinomas.FGFR1 promotes the stem cell-like phenotype of FGFR1-amplified non-small cell lung cancer cells through the Hedgehog pathway.New strategies in squamous cell carcinoma of the lung: identification of tumor drivers to personalize therapy.

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P2860

Sex determining region Y-Box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung.

http://www.wikidata.org/entity/Q33531781

description

2010 nî lūn-bûn

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2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2010 թվականի փետրվարին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Sex determining region Y-Box 2 ...... s cell carcinomas of the lung.

@ast

Sex determining region Y-Box 2 ...... s cell carcinomas of the lung.

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Sex determining region Y-Box 2

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type

label

Sex determining region Y-Box 2 ...... s cell carcinomas of the lung.

@ast

Sex determining region Y-Box 2 ...... s cell carcinomas of the lung.

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Sex determining region Y-Box 2

@nl

prefLabel

Sex determining region Y-Box 2 ...... s cell carcinomas of the lung.

@ast

Sex determining region Y-Box 2 ...... s cell carcinomas of the lung.

@en

Sex determining region Y-Box 2

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Sex determining region Y-Box 2 ...... s cell carcinomas of the lung.

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Carmen Behrens

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Cesar Moran

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Denise Woods

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Edward Kim

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Guosheng Yin

http://www.w3.org/2001/XMLSchema#string

Humam Kadara

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Jiaoti Huang

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John D Minna

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Junya Fujimoto

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Luc Girard

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P2860

Core transcriptional regulatory circuitry in human embryonic stem cells

Genomic profiling identifies TITF1 as a lineage-specific oncogene amplified in lung cancer

Summaries of Affymetrix GeneChip probe level data

ONCOMINE: a cancer microarray database and integrated data-mining platform

Sox2 is important for two crucial processes in lung development: branching morphogenesis and epithelial cell differentiation

Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchless

Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung

Cancer statistics, 2009

Oncogenic pathway signatures in human cancers as a guide to targeted therapies

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Ignacio I Wistuba

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