Targeting Id1 and Id3 by a specific peptide aptamer induces E-box promoter activity, cell cycle arrest, and apoptosis in breast cancer cells.
about
Nanotechnology-mediated targeting of tumor angiogenesisAptamers: A promising chemical antibody for cancer therapyKrüppel-like factor 17, a novel tumor suppressor: its low expression is involved in cancer metastasisId2, Id3 and Id4 overcome a Smad7-mediated block in tumorigenesis, generating TGF-β-independent melanoma.Inhibition of Id proteins by a peptide aptamer induces cell-cycle arrest and apoptosis in ovarian cancer cells.Increased expression of Id1 and Id3 promotes tumorigenicity by enhancing angiogenesis and suppressing apoptosis in small cell lung cancerNucleic acid aptamer-guided cancer therapeutics and diagnostics: the next generation of cancer medicineID proteins regulate diverse aspects of cancer progression and provide novel therapeutic opportunities.Id3 induces an Elk-1-caspase-8-dependent apoptotic pathway in squamous carcinoma cellsMolecular characterization of irinotecan (SN-38) resistant human breast cancer cell lines.Id1 and Id3 expression is associated with increasing grade of prostate cancer: Id3 preferentially regulates CDKN1BId1 and Id3 co-expression correlates with clinical outcome in stage III-N2 non-small cell lung cancer patients treated with definitive chemoradiotherapy.Id1 enhances human ovarian cancer endothelial progenitor cell angiogenesis via PI3K/Akt and NF-κB/MMP-2 signaling pathways.Role of ID Proteins in BMP4 Inhibition of Profibrotic Effects of TGF-β2 in Human TM Cells.An ShRNA Screen Identifies MEIS1 as a Driver of Malignant Peripheral Nerve Sheath Tumors.Footprintless disruption of prosurvival genes in aneuploid cancer cells using CRISPR/Cas9 technology.Effects of upregulation of Id3 in human lung adenocarcinoma cells on proliferation, apoptosis, mobility and tumorigenicity.Inflammation-induced S100A8 activates Id3 and promotes colorectal tumorigenesis.Inhibitor of differentiation 4 (ID4) acts as an inhibitor of ID-1, -2 and -3 and promotes basic helix loop helix (bHLH) E47 DNA binding and transcriptional activity.Targeting the bHLH transcriptional networks by mutated E proteins in experimental glioma.The Id-protein family in developmental and cancer-associated pathways.Bone morphogenetic protein type I receptor antagonists decrease growth and induce cell death of lung cancer cell lines.Structure-activity relationships of a peptidic antagonist of Id1 studied by biosensor method, circular dichroism spectroscopy, and bioassay.Aptamers: a promising tool for cancer imaging, diagnosis, and therapy.Structure activity relationships of peptidic analogs of MyoD for the development of Id1 inhibitors as antiproliferative agents.A new diagnostic algorithm for Burkitt and diffuse large B-cell lymphomas based on the expression of CSE1L and STAT3 and on MYC rearrangement predicts outcome.Expression, function, and regulation of the embryonic transcription factor TBX1 in parathyroid tumors.Targeting of a Helix-Loop-Helix Transcriptional Regulator by a Short Helical Peptide.Structural insights into interacting mechanism of ID1 protein with an antagonist ID1/3-PA7 and agonist ETS-1 in treatment of ovarian cancer: molecular docking and dynamics studies.ID2 and ID3 protein expression mirrors granulopoietic maturation and discriminates between acute leukemia subtypes.Smurfs in Protein Homeostasis, Signaling, and Cancer
P2860
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P2860
Targeting Id1 and Id3 by a specific peptide aptamer induces E-box promoter activity, cell cycle arrest, and apoptosis in breast cancer cells.
description
2010 nî lūn-bûn
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2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
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2010 թվականի փետրվարին հրատարակված գիտական հոդված
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年學術文章
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name
Targeting Id1 and Id3 by a spe ...... ptosis in breast cancer cells.
@ast
Targeting Id1 and Id3 by a spe ...... ptosis in breast cancer cells.
@en
Targeting Id1 and Id3 by a spe ...... ptosis in breast cancer cells.
@nl
type
label
Targeting Id1 and Id3 by a spe ...... ptosis in breast cancer cells.
@ast
Targeting Id1 and Id3 by a spe ...... ptosis in breast cancer cells.
@en
Targeting Id1 and Id3 by a spe ...... ptosis in breast cancer cells.
@nl
prefLabel
Targeting Id1 and Id3 by a spe ...... ptosis in breast cancer cells.
@ast
Targeting Id1 and Id3 by a spe ...... ptosis in breast cancer cells.
@en
Targeting Id1 and Id3 by a spe ...... ptosis in breast cancer cells.
@nl
P2093
P1476
Targeting Id1 and Id3 by a spe ...... ptosis in breast cancer cells.
@en
P2093
Demissew S Mern
Felix Hoppe-Seyler
Jens Hasskarl
Karin Hoppe-Seyler
P2860
P2888
P304
P356
10.1007/S10549-010-0810-6
P407
P577
2010-02-27T00:00:00Z
P5875
P6179
1013045363