Assessment of in silico models for fraction of unbound drug in human liver microsomes.
about
Developing a Physiologically-Based Pharmacokinetic Model Knowledgebase in Support of Provisional Model ConstructionAgent-based simulation of reactions in the crowded and structured intracellular environment: Influence of mobility and location of the reactantsIn silico ADME/T modelling for rational drug design.Application of IVIVE and PBPK modeling in prospective prediction of clinical pharmacokinetics: strategy and approach during the drug discovery phase with four case studies.Regioselective glucuronidation of gingerols by human liver microsomes and expressed UDP-glucuronosyltransferase enzymes: reaction kinetics and activity correlation analyses for UGT1A9 and UGT2B7.Impact of low-dose ritonavir on danoprevir pharmacokinetics: results of computer-based simulations and a clinical drug-drug interaction study.Metabolism of the anthelmintic drug niclosamide by cytochrome P450 enzymes and UDP-glucuronosyltransferases: metabolite elucidation and main contributions from CYP1A2 and UGT1A1.Chemical inhibition and stable knock-down of efflux transporters leads to reduced glucuronidation of wushanicaritin in UGT1A1-overexpressing HeLa cells: the role of breast cancer resistance protein (BCRP) and multidrug resistance-associated proteins
P2860
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P2860
Assessment of in silico models for fraction of unbound drug in human liver microsomes.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Assessment of in silico models for fraction of unbound drug in human liver microsomes.
@ast
Assessment of in silico models for fraction of unbound drug in human liver microsomes.
@en
Assessment of in silico models for fraction of unbound drug in human liver microsomes.
@nl
type
label
Assessment of in silico models for fraction of unbound drug in human liver microsomes.
@ast
Assessment of in silico models for fraction of unbound drug in human liver microsomes.
@en
Assessment of in silico models for fraction of unbound drug in human liver microsomes.
@nl
prefLabel
Assessment of in silico models for fraction of unbound drug in human liver microsomes.
@ast
Assessment of in silico models for fraction of unbound drug in human liver microsomes.
@en
Assessment of in silico models for fraction of unbound drug in human liver microsomes.
@nl
P2093
P2860
P1476
Assessment of in silico models for fraction of unbound drug in human liver microsomes.
@en
P2093
George Chang
Stefanus J Steyn
P2860
P304
P356
10.1517/17425251003671022
P407
P577
2010-05-01T00:00:00Z