Physiological modeling to understand the impact of enzymes and transporters on drug and metabolite data and bioavailability estimates.

Physiological modeling to understand the impact of enzymes and transporters on drug and metabolite data and bioavailability estimates.

Item
http://www.wikidata.org/entity/Q33550408
Predicting Drug Extraction in the Human Gut Wall: Assessing Contributions from Drug Metabolizing Enzymes and Transporter Proteins using Preclinical ModelsPhysiologically based pharmacokinetic modeling: methodology, applications, and limitations with a focus on its role in pediatric drug development.Physiologically based pharmacokinetic (PBPK) modelling tools: how to fit with our needs?Current toxicological aspects on drug and chemical transport and metabolism across the human placental barrier.Prediction of pharmacokinetics and drug-drug interactions when hepatic transporters are involved.Dealing with the complex drug-drug interactions: towards mechanistic models.Physiologically based pharmacokinetic modeling revealed minimal codeine intestinal metabolism in first-pass removal in rats.Metabolite Kinetics: The Segregated Flow Model for Intestinal and Whole Body Physiologically Based Pharmacokinetic Modeling to Describe Intestinal and Hepatic Glucuronidation of Morphine in Rats In Vivo.A weak C' box renders U3 snoRNA levels dependent on hU3-55K binding.Unequivocal evidence supporting the segregated flow intestinal model that discriminates intestine versus liver first-pass removal with PBPK modeling.
P2860

Physiological modeling to understand the impact of enzymes and transporters on drug and metabolite data and bioavailability estimates.

Item
http://www.wikidata.org/entity/Q33550408
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Physiological modeling to unde ...... and bioavailability estimates.
@ast
Physiological modeling to unde ...... and bioavailability estimates.
@en
Physiological modeling to unde ...... and bioavailability estimates.
@nl
type
label
Physiological modeling to unde ...... and bioavailability estimates.
@ast
Physiological modeling to unde ...... and bioavailability estimates.
@en
Physiological modeling to unde ...... and bioavailability estimates.
@nl
prefLabel
Physiological modeling to unde ...... and bioavailability estimates.
@ast
Physiological modeling to unde ...... and bioavailability estimates.
@en
Physiological modeling to unde ...... and bioavailability estimates.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P698
P356
P1433
P1476
Physiological modeling to unde ...... and bioavailability estimates.
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P698