Probing the salt bridge in the dihydrofolate reductase-methotrexate complex by using the coordinate-coupled free-energy perturbation method
about
Structural basis for the enhanced thermal stability of alcohol dehydrogenase mutants from the mesophilic bacterium Clostridium beijerinckii: contribution of salt bridgingElectrostatic strengths of salt bridges in thermophilic and mesophilic glutamate dehydrogenase monomers.Contribution of salt bridges toward protein thermostability.The methionine-aromatic motif plays a unique role in stabilizing protein structure.A free-energy perturbation study of the binding of methotrexate to mutants of dihydrofolate reductaseEffects of fluorine substitution on the structure and dynamics of complexes of dihydrofolate reductase (Escherichia coli).Relationship between ion pair geometries and electrostatic strengths in proteins.Interactions between ionizable amino acid side chains at a lipid bilayer-water interface.Minimum MD simulation length required to achieve reliable results in free energy perturbation calculations: case study of relative binding free energies of fructose-1,6-bisphosphatase inhibitors.
P2860
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P2860
Probing the salt bridge in the dihydrofolate reductase-methotrexate complex by using the coordinate-coupled free-energy perturbation method
description
1988 nî lūn-bûn
@nan
1988 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Probing the salt bridge in the ...... ree-energy perturbation method
@ast
Probing the salt bridge in the ...... ree-energy perturbation method
@en
Probing the salt bridge in the ...... ee-energy perturbation method.
@nl
type
label
Probing the salt bridge in the ...... ree-energy perturbation method
@ast
Probing the salt bridge in the ...... ree-energy perturbation method
@en
Probing the salt bridge in the ...... ee-energy perturbation method.
@nl
prefLabel
Probing the salt bridge in the ...... ree-energy perturbation method
@ast
Probing the salt bridge in the ...... ree-energy perturbation method
@en
Probing the salt bridge in the ...... ee-energy perturbation method.
@nl
P2860
P356
P1476
Probing the salt bridge in the ...... ree-energy perturbation method
@en
P2093
P2860
P304
P356
10.1073/PNAS.85.12.4280
P407
P577
1988-06-01T00:00:00Z