A free-energy perturbation study of the binding of methotrexate to mutants of dihydrofolate reductase
about
Refolding of Escherichia coli dihydrofolate reductase: sequential formation of substrate binding sites.Decomposing the energetic impact of drug resistant mutations in HIV-1 protease on binding DRV.Effects of fluorine substitution on the structure and dynamics of complexes of dihydrofolate reductase (Escherichia coli).Molecular Basis for Drug Resistance in HIV-1 ProteaseOn achieving better than 1-A accuracy in a simulation of a large protein: Streptomyces griseus protease ARelative differences in the binding free energies of human immunodeficiency virus 1 protease inhibitors: a thermodynamic cycle-perturbation approachMinimum MD simulation length required to achieve reliable results in free energy perturbation calculations: case study of relative binding free energies of fructose-1,6-bisphosphatase inhibitors.Direct determination of vibrational density of states change on ligand binding to a protein.
P2860
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P2860
A free-energy perturbation study of the binding of methotrexate to mutants of dihydrofolate reductase
description
1988 nî lūn-bûn
@nan
1988 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年学术文章
@wuu
1988年学术文章
@zh-cn
1988年学术文章
@zh-hans
1988年学术文章
@zh-my
1988年学术文章
@zh-sg
1988年學術文章
@yue
name
A free-energy perturbation stu ...... nts of dihydrofolate reductase
@ast
A free-energy perturbation stu ...... nts of dihydrofolate reductase
@en
type
label
A free-energy perturbation stu ...... nts of dihydrofolate reductase
@ast
A free-energy perturbation stu ...... nts of dihydrofolate reductase
@en
prefLabel
A free-energy perturbation stu ...... nts of dihydrofolate reductase
@ast
A free-energy perturbation stu ...... nts of dihydrofolate reductase
@en
P2860
P356
P1476
A free-energy perturbation stu ...... nts of dihydrofolate reductase
@en
P2093
S J Benkovic
P2860
P304
P356
10.1073/PNAS.85.24.9519
P407
P577
1988-12-01T00:00:00Z