Mutagenic specificity of solar UV light in nucleotide excision repair-deficient rodent cells.
about
UVA radiation is highly mutagenic in cells that are unable to repair 7,8-dihydro-8-oxoguanine in Saccharomyces cerevisiae.Recombination-dependent deletion formation in mammalian cells deficient in the nucleotide excision repair gene ERCC12'-Deoxycytidine glycols, a missing link in the free radical-mediated oxidation of DNA.Wavelength dependence of ultraviolet radiation-induced DNA damage as determined by laser irradiation suggests that cyclobutane pyrimidine dimers are the principal DNA lesions produced by terrestrial sunlight.Excision repair is required for genotoxin-induced mutagenesis in mammalian cells.Genome-wide comparison of human keratinocyte and squamous cell carcinoma responses to UVB irradiation: implications for skin and epithelial cancer.Unravelling UVA-induced mutagenesis.Cyclobutane pyrimidine dimers are predominant DNA lesions in whole human skin exposed to UVA radiation.UV signature mutations.UVA-induced cyclobutane pyrimidine dimers form predominantly at thymine-thymine dipyrimidines and correlate with the mutation spectrum in rodent cells.Identification of potentially cytotoxic lesions induced by UVA photoactivation of DNA 4-thiothymidine in human cellsXeroderma pigmentosum: from genetics to hopes and realities of cutaneous gene therapy.UVB induces atypical melanocytic lesions and melanoma in human skin.Mutagenicity of ultraviolet A radiation in the lacI transgene in Big Blue mouse embryonic fibroblastsUVA-induced DNA double-strand breaks result from the repair of clustered oxidative DNA damages.DNA damage in human pterygium: one-shot multiple targets.Formation of cyclobutane pyrimidine dimers at dipyrimidines containing 5-hydroxymethylcytosine.DNA-lesion mapping in mammalian cellsRapid repair of UVA-induced oxidized purines and persistence of UVB-induced dipyrimidine lesions determine the mutagenicity of sunlight in mouse cellsCellular and sub-cellular responses to UVA in relation to carcinogenesis.Signature p53 mutation at DNA cross-linking sites in 8-methoxypsoralen and ultraviolet A (PUVA)-induced murine skin cancers.A novel p53 mutational hotspot in skin tumors from UV-irradiated Xpc mutant mice alters transactivation functions.Nuclear and non-nuclear targets of genotoxic agents in the induction of gene expression. Shared principles in yeast, rodents, man and plants.Rapid degradation of longer DNA fragments enables the improved estimation of distribution and biomass using environmental DNA.Can skin cancer in humans be prevented by alleviation of oxidative stress?Comet assay combined with p53 detection as a sensitive approach for DNA photoprotection assessment in vitro.Far-UV-lnduced Dimeric Photoproducts in Short Oligonucleotides: Sequence Effects
P2860
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P2860
Mutagenic specificity of solar UV light in nucleotide excision repair-deficient rodent cells.
description
1996 nî lūn-bûn
@nan
1996 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Mutagenic specificity of solar ...... repair-deficient rodent cells.
@ast
Mutagenic specificity of solar ...... repair-deficient rodent cells.
@en
type
label
Mutagenic specificity of solar ...... repair-deficient rodent cells.
@ast
Mutagenic specificity of solar ...... repair-deficient rodent cells.
@en
prefLabel
Mutagenic specificity of solar ...... repair-deficient rodent cells.
@ast
Mutagenic specificity of solar ...... repair-deficient rodent cells.
@en
P2093
P2860
P356
P1476
Mutagenic specificity of solar ...... repair-deficient rodent cells.
@en
P2093
Chteauneuf A
Drobetsky EA
Moustacchi E
P2860
P304
P356
10.1073/PNAS.93.1.176
P407
P577
1996-01-01T00:00:00Z