Restricted ultraviolet mutational spectrum in a shuttle vector propagated in xeroderma pigmentosum cells.
about
Multiple mutations and frameshifts are the hallmark of defective hPMS2 in pZ189-transfected human tumor cellsXPA protein alters the specificity of ultraviolet light-induced mutagenesis in vitro.Joining of linear plasmid DNA is reduced and error-prone in Bloom's syndrome cells.DNA base sequence changes and sequence specificity of bromodeoxyuridine-induced mutations in mammalian cells.Mutagenic specificity of solar UV light in nucleotide excision repair-deficient rodent cells.Molecular epidemiology of human cancer risk: gene-environment interactions and p53 mutation spectrum in human lung cancer.Unique pattern of point mutations arising after gene transfer into mammalian cells.Conversion of normal to malignant phenotype: telomere shortening, telomerase activation, and genomic instability during immortalization of human oral keratinocytes.The specificity of UV-induced mutations at an endogenous locus in mammalian cells.Inhibition of initiation of simian virus 40 DNA replication during acute response of cells irradiated by ultraviolet light.Photoproduct frequency is not the major determinant of UV base substitution hot spots or cold spots in human cellsKinds of mutations formed when a shuttle vector containing adducts of (+/-)-7 beta, 8 alpha-dihydroxy-9 alpha, 10 alpha-epoxy-7,8,9, 10-tetrahydrobenzo[a]pyrene replicates in human cells.Multiple point mutations in a shuttle vector propagated in human cells: evidence for an error-prone DNA polymerase activity.Deletions at short direct repeats and base substitutions are characteristic mutations for bleomycin-induced double- and single-strand breaks, respectively, in a human shuttle vector system.UV signature mutations.Forty years of research on xeroderma pigmentosum at the US National Institutes of Health.Abnormal ultraviolet mutagenic spectrum in plasmid DNA replicated in cultured fibroblasts from a patient with the skin cancer-prone disease, xeroderma pigmentosumMutagenic properties of the T-C cyclobutane dimer.Transcriptional bypass of bulky DNA lesions causes new mutant RNA transcripts in human cellsShining a light on xeroderma pigmentosum.Modulation of an ultraviolet mutational hotspot in a shuttle vector Xeroderma cells.Repair and replication of plasmids with site-specific 8-oxodG and 8-AAFdG residues in normal and repair-deficient human cells.UV-induced mutagenesis of human p53 in a vector replicated in Saccharomyces cerevisiae.Protein oxidative damage is associated with life expectancy of housefliesUltraviolet-induced mutations in Cockayne syndrome cells are primarily caused by cyclobutane dimer photoproducts while repair of other photoproducts is normal.Replication of UV-irradiated DNA in human cell extracts: evidence for mutagenic bypass of pyrimidine dimers.Specific UV-induced mutation spectrum in the p53 gene of skin tumors from DNA-repair-deficient xeroderma pigmentosum patientsReplication and mutagenesis of UV-damaged DNA templates in human and monkey cell extractsEvidence from mutation spectra that the UV hypermutability of xeroderma pigmentosum variant cells reflects abnormal, error-prone replication on a template containing photoproducts.Rapid and apparently error-prone excision repair of nonreplicating UV-irradiated plasmids in Xenopus laevis oocytesKinds and spectrum of mutations induced by 1-nitrosopyrene adducts during plasmid replication in human cellsUse of a simian virus 40-based shuttle vector to analyze enhanced mutagenesis in mitomycin C-treated monkey cells.Determination of the spectrum of mutations induced by defined-wavelength solar UVB (313-nm) radiation in mammalian cells by use of a shuttle vectorReplication fork bypass of a pyrimidine dimer blocking leading strand DNA synthesis.Unique DNA repair properties of a xeroderma pigmentosum revertant.Mutation in a reporter gene depends on proximity to and transcription of immunoglobulin variable transgenes.Xeroderma pigmentosum variant cells are less likely than normal cells to incorporate dAMP opposite photoproducts during replication of UV-irradiated plasmidsMolecular fingerprints of environmental carcinogens in human cancer.A review of some topics concerning mutagenesis by ultraviolet light.Respective roles of pyrimidine dimer and pyrimidine (6-4) pyrimidone photoproducts in UV mutagenesis of simian virus 40 DNA in mammalian cells.
P2860
Q22254326-CE8451AE-F63C-4A36-851C-7817BAEA91DDQ31928055-B6CDE31E-FDE5-4199-86BF-72AD4DC697C2Q33564824-5298E59D-6E9E-4AF2-A2BC-93697F95D15BQ33582091-800E4CEC-2936-4AAE-8F3E-D4CD52F3306AQ33607059-8E6605B0-830C-41DD-8738-40E3C8717C99Q33643298-40EA5AA4-B5CA-4ACE-A0A5-D5A950ED1109Q33928718-8510288F-5AA2-497F-9FC6-C9DC2B58C767Q34249547-19FD63C4-3F05-4407-8FB7-E5A567A0A907Q34379440-9092A81E-B4C8-4AEE-8FEA-3D01D3E18F0FQ34607368-A95D6361-D2FB-494E-A973-EFBF7960F78BQ34627971-4E05EF53-B03B-447F-802D-BDAE4FAD035CQ34628034-F5A6AE39-215D-42B0-8567-1D264A8D1D2FQ34639696-0F7014B7-4A21-423F-9C05-680B5624E33EQ34767915-ADC0B7F3-F51C-4C00-94D3-640E2D61DE1EQ34963798-8AB8C0AB-4228-4EBD-B912-444030A8705EQ35164298-C083151D-3189-4744-A540-7654E4ADB6C6Q35582966-06809956-7AD3-41D9-8BB9-7F2E4CB87D85Q35622541-32F3491E-3550-4E6B-A47B-5860118C5F9CQ35752678-BB108EAE-16EA-488D-BC0D-1120F2B2D890Q35757364-08A9F946-4CB5-47E4-952B-E536FABBE7E0Q35919559-5C332E71-C4B9-4D7C-8416-21C5B208BE4AQ35926583-9A158535-D041-4E1E-8E94-417C239A01E0Q36035680-B5DB1788-1B43-4885-A7E1-8C46FB044725Q36458801-4698C911-8ED1-4A4A-8FC3-E4CD0642059EQ36458963-E0B9CF49-FF35-4738-B8E7-357C408F90E6Q36487817-B376C13A-B8B9-4D8A-846D-A5533EE1279CQ36659736-0A0A1C7C-4119-49CD-BA41-9AFABB2D7E99Q36659778-8D540E96-2F56-4891-8A6A-F615C787967EQ36690666-CDB017C3-9391-42F2-A9BF-DCC5326E3462Q36715358-4072AD7E-54A2-47EE-89DA-B0DB01540AD7Q36793418-3E6A45D0-8264-4586-AE3C-9241F0CD03D7Q36845722-9839238E-373A-4751-8A80-4B87E8E41165Q36850841-15AF4BD7-460D-4535-9815-BA5216B6B1C4Q36861158-9036C8F2-0944-4E73-81AC-B2E05CA4B255Q36921671-6AEFF2EB-7855-45C5-ABAC-E2D1739B4F7CQ37525213-8BB97B65-A18B-4997-AC10-7ABC82AB38FCQ37588195-336F6571-0AF0-4B67-8EAB-3844DA20A5F2Q38507277-80C50B42-6F5C-45BA-BBB8-1968435E761CQ39667528-16C38A1A-02AC-4FB4-A682-81FC308D7133Q40117296-E5A2E492-F040-4638-B566-98713A8603C7
P2860
Restricted ultraviolet mutational spectrum in a shuttle vector propagated in xeroderma pigmentosum cells.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年学术文章
@wuu
1986年学术文章
@zh-cn
1986年学术文章
@zh-hans
1986年学术文章
@zh-my
1986年学术文章
@zh-sg
1986年學術文章
@yue
1986年學術文章
@zh
1986年學術文章
@zh-hant
name
Restricted ultraviolet mutatio ...... n xeroderma pigmentosum cells.
@en
Restricted ultraviolet mutatio ...... n xeroderma pigmentosum cells.
@nl
type
label
Restricted ultraviolet mutatio ...... n xeroderma pigmentosum cells.
@en
Restricted ultraviolet mutatio ...... n xeroderma pigmentosum cells.
@nl
prefLabel
Restricted ultraviolet mutatio ...... n xeroderma pigmentosum cells.
@en
Restricted ultraviolet mutatio ...... n xeroderma pigmentosum cells.
@nl
P2093
P2860
P356
P1476
Restricted ultraviolet mutatio ...... n xeroderma pigmentosum cells.
@en
P2093
A Bredberg
K H Kraemer
M M Seidman
P2860
P304
P356
10.1073/PNAS.83.21.8273
P407
P577
1986-11-01T00:00:00Z