The specificity of UV-induced mutations at an endogenous locus in mammalian cells.
about
Integrative analysis of the melanoma transcriptomeMelanoma genome sequencing reveals frequent PREX2 mutationsMutagenic specificity of solar UV light in nucleotide excision repair-deficient rodent cells.Mutation signatures of carcinogen exposure: genome-wide detection and new opportunities for cancer prevention.Rapid detection of ultraviolet-induced reversion of an amber mutation in mouse L cellsHypomutability in Fanconi anemia cells is associated with increased deletion frequency at the HPRT locus.8-Methoxypsoralen induced mutations are highly targeted at crosslinkable sites of photoaddition on the non-transcribed strand of a mammalian chromosomal gene.Mutagen-specific mutation signature determines global microRNA binding.A role for ultraviolet A in solar mutagenesis.UV signature mutations.A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma.Revisiting the photochemistry of solar UVA in human skin.UVA-induced cyclobutane pyrimidine dimers form predominantly at thymine-thymine dipyrimidines and correlate with the mutation spectrum in rodent cells.Evidence for recent, population-specific evolution of the human mutation rateMutations in ras genes in cells cultured from mouse skin tumors induced by ultraviolet irradiation.Mutagenic properties of the T-C cyclobutane dimer.Strand specificity for UV-induced DNA repair and mutations in the Chinese hamster HPRT geneHigh levels of patched gene mutations in basal-cell carcinomas from patients with xeroderma pigmentosum.Replication of UV-irradiated DNA in human cell extracts: evidence for mutagenic bypass of pyrimidine dimers.Specific UV-induced mutation spectrum in the p53 gene of skin tumors from DNA-repair-deficient xeroderma pigmentosum patientsCell cycle-dependent strand bias for UV-induced mutations in the transcribed strand of excision repair-proficient human fibroblasts but not in repair-deficient cellsEvidence from mutation spectra that the UV hypermutability of xeroderma pigmentosum variant cells reflects abnormal, error-prone replication on a template containing photoproducts.Nonsense mutations in the dihydrofolate reductase gene affect RNA processing.N-ras mutations in human cutaneous melanoma from sun-exposed body sites.Determination of the spectrum of mutations induced by defined-wavelength solar UVB (313-nm) radiation in mammalian cells by use of a shuttle vectorA threshold of endogenous stress is required to engage cellular response to protect against mutagenesis.In vivo mapping of a DNA adduct at nucleotide resolution: detection of pyrimidine (6-4) pyrimidone photoproducts by ligation-mediated polymerase chain reactionCellular and sub-cellular responses to UVA in relation to carcinogenesis.Mechanisms and consequences of mutation induction in mammalian cells.Abnormal, error-prone bypass of photoproducts by xeroderma pigmentosum variant cell extracts results in extreme strand bias for the kinds of mutations induced by UV light.Specific tandem GG to TT base substitutions induced by acetaldehyde are due to intra-strand crosslinks between adjacent guanine bases.Respective roles of pyrimidine dimer and pyrimidine (6-4) pyrimidone photoproducts in UV mutagenesis of simian virus 40 DNA in mammalian cells.DNA strand specificity for UV-induced mutations in mammalian cells.Mutational spectrum of the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis.Multiple mutations are common at mouse Aprt in genotoxin-exposed mismatch repair deficient cells.Assessment of genotoxicity and mutagenicity of 1,2-dioxetanes in human cells using a plasmid shuttle vector.Developmental genes and cancer: role of patched in basal cell carcinoma of the skin.Multiple dispersed spontaneous mutations: a novel pathway of mutation in a malignant human cell lineAltered oncogenes in UV-transformed C3H 10T1/2 mouse cells: identification of mutated H-ras allele(s).Ultraviolet-induced p53 mutations in atypical fibroxanthoma
P2860
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P2860
The specificity of UV-induced mutations at an endogenous locus in mammalian cells.
description
1987 nî lūn-bûn
@nan
1987 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1987 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
name
The specificity of UV-induced mutations at an endogenous locus in mammalian cells.
@ast
The specificity of UV-induced mutations at an endogenous locus in mammalian cells.
@en
The specificity of UV-induced mutations at an endogenous locus in mammalian cells.
@nl
type
label
The specificity of UV-induced mutations at an endogenous locus in mammalian cells.
@ast
The specificity of UV-induced mutations at an endogenous locus in mammalian cells.
@en
The specificity of UV-induced mutations at an endogenous locus in mammalian cells.
@nl
prefLabel
The specificity of UV-induced mutations at an endogenous locus in mammalian cells.
@ast
The specificity of UV-induced mutations at an endogenous locus in mammalian cells.
@en
The specificity of UV-induced mutations at an endogenous locus in mammalian cells.
@nl
P2093
P2860
P356
P1476
The specificity of UV-induced mutations at an endogenous locus in mammalian cells.
@en
P2093
Drobetsky EA
Glickman BW
Grosovsky AJ
P2860
P304
P356
10.1073/PNAS.84.24.9103
P407
P577
1987-12-01T00:00:00Z