Activation of sphingosine 1-phosphate receptor-1 by FTY720 is neuroprotective after ischemic stroke in rats. - Wikidata - awgldk - TriplyDB

Activation of sphingosine 1-phosphate receptor-1 by FTY720 is neuroprotective after ischemic stroke in rats.

Activation of sphingosine 1-phosphate receptor-1 by FTY720 is neuroprotective after ischemic stroke in rats.

http://www.wikidata.org/entity/Q33611979

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The SphKs/S1P/S1PR1 axis in immunity and cancer: more ore to be mined Rational modulation of the innate immune system for neuroprotection in ischemic stroke Sphingolipids in spinal cord injury Fingolimod for the treatment of neurological diseases-state of play and future perspectives FTY720 treatment in the convalescence period improves functional recovery and reduces reactive astrogliosis in photothrombotic stroke Sphingosine-1-Phosphate Receptor-1 Selective Agonist Enhances Collateral Growth and Protects against Subsequent Stroke FTY720 reduces post-ischemic brain lymphocyte influx but does not improve outcome in permanent murine cerebral ischemia Fingolimod Limits Acute Aβ Neurotoxicity and Promotes Synaptic Versus Extrasynaptic NMDA Receptor Functionality in Hippocampal Neurons Innate inflammatory responses in stroke: mechanisms and potential therapeutic targets.Isoflurane posttreatment reduces neonatal hypoxic-ischemic brain injury in rats by the sphingosine-1-phosphate/phosphatidylinositol-3-kinase/Akt pathway.Activation of immune responses to brain antigens after stroke.Mechanisms of osteopontin-induced stabilization of blood-brain barrier disruption after subarachnoid hemorrhage in rats Antigen-specific immune reactions to ischemic stroke.MALDI-mass spectrometry imaging of desalted rat brain sections reveals ischemia-mediated changes of lipids.An update on sphingosine-1-phosphate and other sphingolipid mediators.Ozanimod (RPC1063) is a potent sphingosine-1-phosphate receptor-1 (S1P1 ) and receptor-5 (S1P5 ) agonist with autoimmune disease-modifying activity.Treatment with the immunomodulator FTY720 does not promote spontaneous bacterial infections after experimental stroke in mice.Impact of an immune modulator fingolimod on acute ischemic stroke.Protective role of fingolimod (FTY720) in rats subjected to subarachnoid hemorrhage.S1P1 receptor modulation preserves vascular function in mesenteric and coronary arteries after CPB in the rat independent of depletion of lymphocytes.Changes in the metabolism of sphingolipids after subarachnoid hemorrhage.Sphingosine-1-phosphate signaling and its role in disease.Sphingolipids in cardiovascular diseases and metabolic disorders Importance of T lymphocytes in brain injury, immunodeficiency, and recovery after cerebral ischemia.Artesunate Protected Blood-Brain Barrier via Sphingosine 1 Phosphate Receptor 1/Phosphatidylinositol 3 Kinase Pathway After Subarachnoid Hemorrhage in Rats.Ethanol triggers sphingosine 1-phosphate elevation along with neuroapoptosis in the developing mouse brain.The flavonoid fisetin attenuates postischemic immune cell infiltration, activation and infarct size after transient cerebral middle artery occlusion in mice Junctional protein regulation by sphingosine kinase 2 contributes to blood-brain barrier protection in hypoxic preconditioning-induced cerebral ischemic tolerance.The immunosuppressant FTY720 prolongs survival in a mouse model of diet-induced coronary atherosclerosis and myocardial infarction.Sphingosine 1-phosphate receptor 5 mediates the immune quiescence of the human brain endothelial barrier.Macrophage-Derived Angiopoietin-Like Protein 2 Exacerbates Brain Damage by Accelerating Acute Inflammation after Ischemia-Reperfusion Fingolimod, a sphingosine-1 phosphate receptor modulator, increases BDNF levels and improves symptoms of a mouse model of Rett syndrome.Exogenous S1P Exposure Potentiates Ischemic Stroke Damage That Is Reduced Possibly by Inhibiting S1P Receptor Signaling.Neuroprotective effects of adjunctive treatments for acute stroke thrombolysis: a review of clinical evidence.Influence of inflammation on poststroke plasticity Splenic immune cells in experimental neonatal hypoxia-ischemia Sphingolipids in cardiovascular and cerebrovascular systems: Pathological implications and potential therapeutic targets.Acute splenic irradiation reduces brain injury in the rat focal ischemic stroke model.Mechanism of Action and Clinical Potential of Fingolimod for the Treatment of Stroke.Role of the sphingosine metabolism pathway on neurons against experimental cerebral ischemia in rats

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P2860

Activation of sphingosine 1-phosphate receptor-1 by FTY720 is neuroprotective after ischemic stroke in rats.

http://www.wikidata.org/entity/Q33611979

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2009 nî lūn-bûn

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2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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Activation of sphingosine 1-ph ...... after ischemic stroke in rats.

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Activation of sphingosine 1-ph ...... after ischemic stroke in rats.

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Activation of sphingosine 1-ph ...... after ischemic stroke in rats.

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Activation of sphingosine 1-ph ...... after ischemic stroke in rats.

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Activation of sphingosine 1-ph ...... after ischemic stroke in rats.

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Activation of sphingosine 1-ph ...... after ischemic stroke in rats

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Hidenori Suzuki

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Takumi Sozen

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William Rolland

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Yu Hasegawa

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P2860

Neuronal necrosis after middle cerebral artery occlusion in Wistar rats progresses at different time intervals in the caudoputamen and the cortex.

FTY720: altered lymphocyte traffic results in allograft protection.

Oral fingolimod (FTY720) for relapsing multiple sclerosis.

Signaling of sphingosine-1-phosphate via the S1P/EDG-family of G-protein-coupled receptors.

FTY720: sphingosine 1-phosphate receptor-1 in the control of lymphocyte egress and endothelial barrier function.

FTY720, a new class of immunomodulator, inhibits lymphocyte egress from secondary lymphoid tissues and thymus by agonistic activity at sphingosine 1-phosphate receptors.

Brain sphingosine-1-phosphate receptors: implication for FTY720 in the treatment of multiple sclerosis.

Multifaceted roles of sphingosine-1-phosphate: how does this bioactive sphingolipid fit with acute neurological injury?

Dual roles of the MAPK/ERK1/2 cell signaling pathway after stroke.

The immune modulator FTY720 targets sphingosine 1-phosphate receptors.

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