Wnt signaling activation and mammary gland hyperplasia in MMTV-LRP6 transgenic mice: implication for breast cancer tumorigenesis. - Wikidata - awgldk - TriplyDB

Wnt signaling activation and mammary gland hyperplasia in MMTV-LRP6 transgenic mice: implication for breast cancer tumorigenesis.

Wnt signaling activation and mammary gland hyperplasia in MMTV-LRP6 transgenic mice: implication for breast cancer tumorigenesis.

http://www.wikidata.org/entity/Q33618690

about

A systematic screen for micro-RNAs regulating the canonical Wnt pathway Mammary Development and Breast Cancer: A Wnt Perspective Targeting cancer stem cells by using the nanoparticles Niclosamide suppresses cancer cell growth by inducing Wnt co-receptor LRP6 degradation and inhibiting the Wnt/β-catenin pathway Targeting beta-catenin signaling to induce apoptosis in human breast cancer cells by z-guggulsterone and Gugulipid extract of Ayurvedic medicine plant Commiphora mukul.The cytoplasmic domain of MUC1 induces hyperplasia in the mammary gland and correlates with nuclear accumulation of β-catenin.Differentiation generates paracrine cell pairs that maintain basaloid mouse mammary tumors: proof of concept.Upregulation of the Wnt co-receptor LRP6 promotes hepatocarcinogenesis and enhances cell invasion Nestin positively regulates the Wnt/β-catenin pathway and the proliferation, survival and invasiveness of breast cancer stem cells.Key signaling nodes in mammary gland development and cancer: β-catenin.Wnt pathway activity in breast cancer sub-types and stem-like cells DEAD-box protein p68 is regulated by β-catenin/transcription factor 4 to maintain a positive feedback loop in control of breast cancer progression Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells.Rad6B acts downstream of Wnt signaling to stabilize β-catenin: Implications for a novel Wnt/β-catenin target.Wnt-β-catenin-Tcf-4 signalling-modulated invasiveness is dependent on osteopontin expression in breast cancer.Mesd is a general inhibitor of different Wnt ligands in Wnt/LRP signaling and inhibits PC-3 tumor growth in vivo.Transcriptome analysis of Wnt3a-treated triple-negative breast cancer cells.Diagnostic value of SFRP1 as a favorable predictive and prognostic biomarker in patients with prostate cancer.The pan-PI3K inhibitor GDC-0941 activates canonical WNT signaling to confer resistance in TNBC cells: resistance reversal with WNT inhibitor.Both LRP5 and LRP6 receptors are required to respond to physiological Wnt ligands in mammary epithelial cells and fibroblasts.Wnt signaling in mammary glands: plastic cell fates and combinatorial signaling.Functional consequences of WNT3/Frizzled7-mediated signaling in non-transformed hepatic cells.SOX9 regulates low density lipoprotein receptor-related protein 6 (LRP6) and T-cell factor 4 (TCF4) expression and Wnt/β-catenin activation in breast cancer.The Wnt/β-catenin signaling/Id2 cascade mediates the effects of hypoxia on the hierarchy of colorectal-cancer stem cells CWP232228 targets liver cancer stem cells through Wnt/β-catenin signaling: a novel therapeutic approach for liver cancer treatment Emerging evidence of the physiological role of hypoxia in mammary development and lactation.Potential therapeutic targets of Guggulsterone in cancer The various roles of ubiquitin in Wnt pathway regulation.β-catenin as a potential key target for tumor suppression.Wnt signalling in murine postnatal mammary gland development.The Wnt/β-catenin signaling pathway: a potential therapeutic target in the treatment of triple negative breast cancer.Regulation of Wnt/β-catenin signaling by posttranslational modifications Harnessing low-density lipoprotein receptor protein 6 (LRP6) genetic variation and Wnt signaling for innovative diagnostics in complex diseases.Role of Wnt Co-Receptor LRP6 in Triple Negative Breast Cancer Cell Migration and Invasion.MicroRNA-183 suppresses retinoblastoma cell growth, invasion and migration by targeting LRP6.LRP6 is identified as a potential prognostic marker for oral squamous cell carcinoma via MALDI-IMS.LRP6 promotes invasion and metastasis of colorectal cancer through cytoskeleton dynamics.Gigantol inhibits Wnt/β-catenin signaling and exhibits anticancer activity in breast cancer cells.Pattern of LRP6 gene expression in tumoral tissues of colorectal cancer.Substratum stiffness tunes proliferation downstream of Wnt3a in part by regulating integrin-linked kinase and frizzled-1.

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P2860

Wnt signaling activation and mammary gland hyperplasia in MMTV-LRP6 transgenic mice: implication for breast cancer tumorigenesis.

http://www.wikidata.org/entity/Q33618690

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2009 nî lūn-bûn

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2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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Wnt signaling activation and m ...... r breast cancer tumorigenesis.

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Wnt signaling activation and m ...... r breast cancer tumorigenesis.

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Wnt signaling activation and m ...... r breast cancer tumorigenesis.

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Wnt signaling activation and m ...... r breast cancer tumorigenesis.

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LDL-receptor-related proteins in Wnt signal transduction

Activation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signaling

Identification of c-MYC as a target of the APC pathway

39 kDa receptor-associated protein is an ER resident protein and molecular chaperone for LDL receptor-related protein

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

WNT pathway and mammary carcinogenesis: loss of expression of candidate tumor suppressor gene SFRP1 in most invasive carcinomas except of the medullary type

Loss of SFRP1 is associated with breast cancer progression and poor prognosis in early stage tumors

LRP6 expression promotes cancer cell proliferation and tumorigenesis by altering beta-catenin subcellular distribution

Characterization of Wnt-1 and Wnt-2 induced growth alterations and signaling pathways in NIH3T3 fibroblasts

The Wnt co-receptor Lrp6 is required for normal mouse mammary gland development

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