CK1epsilon is required for breast cancers dependent on beta-catenin activity. - Wikidata - awgldk - TriplyDB

CK1epsilon is required for breast cancers dependent on beta-catenin activity.

CK1epsilon is required for breast cancers dependent on beta-catenin activity.

http://www.wikidata.org/entity/Q33620584

about

A systematic screen for micro-RNAs regulating the canonical Wnt pathway Synthetic lethal screens as a means to understand and treat MYC-driven cancers PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury Selective Targeting of CTNBB1-, KRAS- or MYC-Driven Cell Growth by Combinations of Existing Drugs IC261 induces cell cycle arrest and apoptosis of human cancer cells via CK1δ/ɛ and Wnt/β-catenin independent inhibition of mitotic spindle formation.Coexpression and coregulation analysis of time-series gene expression data in estrogen-induced breast cancer cell MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells.Circadian gene variants in cancer.Activation status of Wnt/ß-catenin signaling in normal and neoplastic breast tissues: relationship to HER2/neu expression in human and mouse Distinguishing between driver and passenger mutations in individual cancer genomes by network enrichment analysis.CK1δ kinase activity is modulated by Chk1-mediated phosphorylation.The microtubule-associated protein DCAMKL1 regulates osteoblast function via repression of Runx2 Concurrent gene signatures for han chinese breast cancers Ligand-independent canonical Wnt activity in canine mammary tumor cell lines associated with aberrant LEF1 expression Acquisition of estrogen independence induces TOB1-related mechanisms supporting breast cancer cell proliferation.Functional genomics identifies therapeutic targets for MYC-driven cancer.Casein kinase 1α has a non-redundant and dominant role within the CK1 family in melanoma progression Casein kinase I epsilon interacts with mitochondrial proteins for the growth and survival of human ovarian cancer cells.Targeting Wnt pathways in disease.High casein kinase 1 epsilon levels are correlated with better prognosis in subsets of patients with breast cancer.Therapeutic targeting of casein kinase 1δ in breast cancer Functions of NOD-Like Receptors in Human Diseases.CK1δ: a pharmacologically tractable Achilles' heel of Wnt-driven cancers?Casein kinase 1 epsilon expression predicts poorer prognosis in low T-stage oral cancer patients.Cross-talk between the circadian clock and the cell cycle in cancer.Biological functions of casein kinase 1 isoforms and putative roles in tumorigenesis.Development of highly selective casein kinase 1δ/1ε (CK1δ/ε) inhibitors with potent antiproliferative properties Casein kinases as potential therapeutic targets.Glucocorticoid Receptor β Acts as a Co-activator of T-Cell Factor 4 and Enhances Glioma Cell Proliferation.SS18-SSX fusion protein-induced Wnt/β-catenin signaling is a therapeutic target in synovial sarcoma.WNT/β-catenin pathway is modulated in asthma patients and LPS-stimulated RAW264.7 macrophage cell line.Lentivirus-mediated gene silencing of beta-catenin inhibits growth of human tongue cancer cells.Defective cell cycle checkpoints as targets for anti-cancer therapies.Phosphorylation of human enhancer filamentation 1 (HEF1) stimulates interaction with Polo-like kinase 1 leading to HEF1 localization to focal adhesions.Casein kinase 1-epsilon or 1-delta required for Wnt-mediated intestinal stem cell maintenance.Development of dual casein kinase 1δ/1ε (CK1δ/ε) inhibitors for treatment of breast cancer.Alternative splicing within the Wnt signaling pathway: role in cancer development.Casein Kinase 1 Epsilon Regulates Glioblastoma Cell Survival

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CK1epsilon is required for breast cancers dependent on beta-catenin activity.

http://www.wikidata.org/entity/Q33620584

description

2010 nî lūn-bûn

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2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

CK1epsilon is required for breast cancers dependent on beta-catenin activity.

@ast

CK1epsilon is required for breast cancers dependent on beta-catenin activity.

@en

type

label

CK1epsilon is required for breast cancers dependent on beta-catenin activity.

@ast

CK1epsilon is required for breast cancers dependent on beta-catenin activity.

@en

prefLabel

CK1epsilon is required for breast cancers dependent on beta-catenin activity.

@ast

CK1epsilon is required for breast cancers dependent on beta-catenin activity.

@en

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JOURNAL.PONE.0008979

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CK1epsilon is required for breast cancers dependent on beta-catenin activity.

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Anna C Schinzel

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Ben Wittner

http://www.w3.org/2001/XMLSchema#string

David E Root

http://www.w3.org/2001/XMLSchema#string

Ian F Dunn

http://www.w3.org/2001/XMLSchema#string

Kara Repich

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Leslie Wardwell

http://www.w3.org/2001/XMLSchema#string

Piyush Gupta

http://www.w3.org/2001/XMLSchema#string

Ron Firestein

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Serena J Silver

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So Young Kim

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P2860

Bioconductor: open software development for computational biology and bioinformatics

Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of the CKI gene family

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

Crystal structure of a conformation-selective casein kinase-1 inhibitor

The Wnt signaling pathway in development and disease

Epigenetic suppression of secreted frizzled related protein 1 (SFRP1) expression in human breast cancer

CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity

An inhibitor of casein kinase I epsilon induces phase delays in circadian rhythms under free-running and entrained conditions

Role of translocation in the activation and function of protein kinase B

The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease

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20126544

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