Nucleoside transporters: molecular biology and implications for therapeutic development.
about
Ethanol blocks adenosine uptake via inhibiting the nucleoside transport system in bronchial epithelial cellsNucleoside transporter proteins of Saccharomyces cerevisiae. Demonstration of a transporter (FUI1) with high uridine selectivity in plasma membranes and a transporter (FUN26) with broad nucleoside selectivity in intracellular membranes.Characterization of the transport mechanism and permeant binding profile of the uridine permease Fui1p of Saccharomyces cerevisiae.Functional and molecular characterization of nucleobase transport by recombinant human and rat equilibrative nucleoside transporters 1 and 2. Chimeric constructs reveal a role for the ENT2 helix 5-6 region in nucleobase translocationModulation of adenosine transport by insulin in human umbilical artery smooth muscle cells from normal or gestational diabetic pregnanciesMolecular cloning and functional characterization of inhibitor-sensitive (mENT1) and inhibitor-resistant (mENT2) equilibrative nucleoside transporters from mouse brainIdentification of Cys140 in helix 4 as an exofacial cysteine residue within the substrate-translocation channel of rat equilibrative nitrobenzylthioinosine (NBMPR)-insensitive nucleoside transporter rENT2Extracellular formation and uptake of adenosine during skeletal muscle contraction in the rat: role of adenosine transportersDifferential transport of cytosine-containing nucleosides by recombinant human concentrative nucleoside transporter protein hCNT1Gene expression and thiopurine metabolite profiling in inflammatory bowel disease - novel clues to drug targets and disease mechanisms?Immunocytochemical demonstration of the equilibrative nucleoside transporter rENT1 in rat sinoatrial nodeIdentification of amino acid residues responsible for the pyrimidine and purine nucleoside specificities of human concentrative Na(+) nucleoside cotransporters hCNT1 and hCNT2Genomic analysis of nucleoside transporters in Diptera and functional characterization of DmENT2, a Drosophila equilibrative nucleoside transporter.Role of adenosine kinase in cochlear development and response to noiseAdenosine and the auditory system.Cannabidiol As a Putative Novel Therapy for Diabetic Retinopathy: A Postulated Mechanism of Action as an Entry Point for Biomarker-Guided Clinical Development.Pharmacokinetic Study of Adjuvant Gemcitabine Therapy for Biliary Tract Cancer following Major Hepatectomy (KHBO1101).Xenobiotic, bile acid, and cholesterol transporters: function and regulation.Translational research in pancreatic ductal adenocarcinoma: current evidence and future concepts.Topology of a human equilibrative, nitrobenzylthioinosine (NBMPR)-sensitive nucleoside transporter (hENT1) implicated in the cellular uptake of adenosine and anti-cancer drugs.Differential expression of human equilibrative nucleoside transporter 1 (hENT1) protein in the Reed-Sternberg cells of Hodgkin's disease.A novel in vitro assay to assess phosphorylation of 3'-[(18)F]fluoro-3'-deoxythymidine.Complex regulation of nucleoside transporter expression in epithelial and immune system cells.Transport of physiological nucleosides and anti-viral and anti-neoplastic nucleoside drugs by recombinant Escherichia coli nucleoside-H(+) cotransporter (NupC) produced in Xenopus laevis oocytes.Prodrug based optimal drug delivery via membrane transporter/receptor.Uneven distribution of nucleoside transporters and intracellular enzymatic degradation prevent transport of intact [14C] adenosine across the sheep choroid plexus epithelium as a monolayer in primary culture.Inhibition of an equilibrative nucleoside transporter by cannabidiol: a mechanism of cannabinoid immunosuppression.Implication of the purinergic system in alcohol use disorders.Adenosine as a signaling molecule in the retina: biochemical and developmental aspects.Molecular biology and regulation of nucleoside and nucleobase transporter proteins in eukaryotes and prokaryotes.Human equilibrative nucleoside transporter 1 and carcinoma of the ampulla of Vater: expression differences in tumour histotypes.A metal-containing nucleoside that possesses both therapeutic and diagnostic activity against cancerExtracellular nucleotide metabolism and signaling in the pathophysiology of articular cartilage.Nucleoside anticancer drugs: the role of nucleoside transporters in resistance to cancer chemotherapy.Nucleoside transporters in chronic lymphocytic leukaemia.Extracellular Adenosine Formation by Ecto-5'-Nucleotidase (CD73) Is No Essential Trigger for Early Phase Ischemic PreconditioningNucleoside and nucleobase transporters in parasitic protozoa.A novel small molecule that selectively inhibits glioblastoma cells expressing EGFRvIII.Residue Ile89 in human plasma membrane monoamine transporter influences its organic cation transport activity and sensitivity to inhibition by dilazepEnhancing Drug Efficacy and Therapeutic Index through Cheminformatics-Based Selection of Small Molecule Binary Weapons That Improve Transporter-Mediated Targeting: A Cytotoxicity System Based on Gemcitabine.
P2860
Q22242359-A0B9A01A-85B7-4C9B-9B99-D2608302CFEAQ27934663-6894EBAE-CDBF-4A60-A029-2D0DBF717C3BQ27937092-BA134E26-27ED-4A2D-B434-48DA6D5286D1Q28217218-0F921F4C-8FD1-4090-BD37-83CAD797995EQ28343381-8F11A963-BDF8-4194-8F89-97E30C4073BCQ28344960-45F7C0A8-4FA4-40D6-BA15-1244A80FBF35Q28345550-872596B4-BDB7-44D2-ADE0-9FF47A8286BDQ28365707-A0814D13-3ABD-4D76-87EA-302EA84F49BDQ28377219-B6D19699-309A-4C62-B4EA-0273A342D6BDQ28486322-7B7BA35F-B7DE-456A-8338-28C67A1BEA3BQ28567094-F59789DA-B796-4253-B7DD-1E23BA554550Q28610373-518CCF7A-595C-4523-8056-D3DF7F214545Q30357870-F1F50A83-8DA4-4045-A595-B548151DCFE2Q30474377-32E6810E-5CF8-4365-8143-906E9C3D8380Q30482911-0A24D7D9-F168-4510-842A-25C3F94CA52DQ30497010-3A30EFD1-B1EC-4B1F-94D2-EF84FE8B23B1Q33428122-28546DD1-2886-40A5-A997-62AE51A5C968Q33714593-6513FBBF-7AB2-441F-9DA5-C209F2628909Q34067863-70714C21-D250-48C3-9516-39843035B56EQ34093436-5B740E51-71D4-41DC-942C-07A8C03F0ED7Q34155353-08657043-62AC-441A-B3B7-91E75F6C1B6FQ34267713-364285D8-EBA8-486F-A69F-7F4109B9A436Q34276396-1C14D56A-F26C-4F19-A7B8-A7400AFB00EEQ34282746-972362B5-F9BF-4C91-85C5-F608FDACE891Q34452034-FA034F89-62A4-4EB7-BA77-27CE55229738Q34575217-ACBEE0A4-33C1-40C7-883D-47B8C7359BC5Q34651059-513035CA-2971-43EA-BC1D-5B9288774ABBQ34789609-39174FC6-0ED1-499F-AA37-E7B0788CA7C6Q34961337-5F845A31-00F7-458D-9FD1-004A50B97481Q35003182-15274C28-3A3E-472E-9777-76FA468412DBQ35197256-B62F1DD7-44D1-4560-A9C3-6C7CAE074ED1Q35351955-2319E4D4-C4A5-4A73-8FAE-B243806A1403Q35559241-EC9455C3-44D1-4F7F-8ED7-3945508BF07BQ35567292-72DB5B4E-DC08-41BB-BF85-D7570FB30D2FQ35635321-30063D43-25E7-424D-958E-79512D9E7754Q35742277-D0E65B5C-4385-47E2-BA2E-2A0D8834B673Q35742322-5933E9D3-A0F2-4D84-A2FD-955027D23631Q35757512-4E5B8218-CCD8-4DEC-B5D7-492A73D1F52CQ36024314-AF933795-CA75-4BC7-9B05-2B58E5644D38Q36342657-CF5D706E-0ABD-49FA-9524-47A8D1E27001
P2860
Nucleoside transporters: molecular biology and implications for therapeutic development.
description
1999 nî lūn-bûn
@nan
1999 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
name
Nucleoside transporters: molecular biology and implications for therapeutic development.
@ast
Nucleoside transporters: molecular biology and implications for therapeutic development.
@en
type
label
Nucleoside transporters: molecular biology and implications for therapeutic development.
@ast
Nucleoside transporters: molecular biology and implications for therapeutic development.
@en
prefLabel
Nucleoside transporters: molecular biology and implications for therapeutic development.
@ast
Nucleoside transporters: molecular biology and implications for therapeutic development.
@en
P2093
P1476
Nucleoside transporters: molecular biology and implications for therapeutic development.
@en
P2093
P304
P356
10.1016/S1357-4310(99)01459-8
P577
1999-05-01T00:00:00Z