Site-directed mutagenesis of human beta-adrenergic receptors: substitution of aspartic acid-130 by asparagine produces a receptor with high-affinity agonist binding that is uncoupled from adenylate cyclase.
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Cloning and characterization of a fourth human somatostatin receptorA "genome-to-lead" approach for insecticide discovery: pharmacological characterization and screening of Aedes aegypti D(1)-like dopamine receptorsOverexpression of kinin B1 receptors induces hypertensive response to des-Arg9-bradykinin and susceptibility to inflammationIdentification of CXCR4 domains that support coreceptor and chemokine receptor functionsSelective binding of ligands to beta 1, beta 2 or chimeric beta 1/beta 2-adrenergic receptors involves multiple subsites.Mutational analysis of ligand binding activity of beta 2 adrenergic receptor expressed in Escherichia coliFunctional role of proline and tryptophan residues highly conserved among G protein-coupled receptors studied by mutational analysis of the m3 muscarinic receptorA novel putative G-protein-coupled receptor expressed in lung, heart and lymphoid tissue.Murine cytomegalovirus M78 protein, a G protein-coupled receptor homologue, is a constituent of the virion and facilitates accumulation of immediate-early viral mRNAMolecular Architecture of G Protein-Coupled Receptors.In vitro mutagenesis and the search for structure-function relationships among G protein-coupled receptorsTwo distinct CCR5 domains can mediate coreceptor usage by human immunodeficiency virus type 1.Polymorphisms in the CCR5 genes of African green monkeys and mice implicate specific amino acids in infections by simian and human immunodeficiency virusesIdentification of critical residues involved in ligand binding and G protein signaling in human somatostatin receptor subtype 2.Chimeric dopamine-norepinephrine transporters delineate structural domains influencing selectivity for catecholamines and 1-methyl-4-phenylpyridiniumMechanism of action of des-His1-[Glu9]glucagon amide, a peptide antagonist of the glucagon receptor systemMolecular biology and respiratory disease. 5. Molecular biology of receptors: implications for lung disease.Structure, function, and regulation of adrenergic receptors.Molecular uncoupling of C-C chemokine receptor 5-induced chemotaxis and signal transduction from HIV-1 coreceptor activity.Role of the highly conserved Asp-Arg-Tyr motif in signal transduction of the CB2 cannabinoid receptor.Genetic fine-structural analysis of the Saccharomyces cerevisiae alpha-pheromone receptor.Models of 5-hydroxytryptamine receptors. A review.Mutations and diseases of G protein coupled receptors.Chemical characterization of ligand binding site fragments from turkey beta-adrenergic receptor.Effects of second intracellular loop mutations on signal transduction and internalization of the gonadotropin-releasing hormone receptor.Bacteriorhodopsin chimeras containing the third cytoplasmic loop of bovine rhodopsin activate transducin for GTP/GDP exchange.Cloning of an octopamine/tyramine receptor and plasticity of its expression as a function of adult sexual maturation in the male moth Agrotis ipsilon.G-Protein binding domains of the angiotensin II AT1A receptors mapped with synthetic peptides selected from the receptor sequence.Identification of a conserved switch residue responsible for selective constitutive activation of the beta2-adrenergic receptor.Understanding the effects on constitutive activation and drug binding of a D130N mutation in the β2 adrenergic receptor via molecular dynamics simulation.
P2860
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P2860
Site-directed mutagenesis of human beta-adrenergic receptors: substitution of aspartic acid-130 by asparagine produces a receptor with high-affinity agonist binding that is uncoupled from adenylate cyclase.
description
1988 nî lūn-bûn
@nan
1988 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Site-directed mutagenesis of h ...... oupled from adenylate cyclase.
@ast
Site-directed mutagenesis of h ...... oupled from adenylate cyclase.
@en
type
label
Site-directed mutagenesis of h ...... oupled from adenylate cyclase.
@ast
Site-directed mutagenesis of h ...... oupled from adenylate cyclase.
@en
prefLabel
Site-directed mutagenesis of h ...... oupled from adenylate cyclase.
@ast
Site-directed mutagenesis of h ...... oupled from adenylate cyclase.
@en
P2093
P2860
P356
P1476
Site-directed mutagenesis of h ...... oupled from adenylate cyclase.
@en
P2093
P2860
P304
P356
10.1073/PNAS.85.15.5478
P407
P577
1988-08-01T00:00:00Z