An approach for extensibly profiling the molecular states of cellular subpopulations.
about
Shedding light on filovirus infection with high-content imagingHigh content screening in chemical biology: overview and main challengesA simple high-content cell cycle assay reveals frequent discrepancies between cell number and ATP and MTS proliferation assaysIdentifying and quantifying heterogeneity in high content analysis: application of heterogeneity indices to drug discoveryParameterizing cell-to-cell regulatory heterogeneities via stochastic transcriptional profiles.Closed-form density-based framework for automatic detection of cellular morphology changesIntensity quantile estimation and mapping--a novel algorithm for the correction of image non-uniformity bias in HCS data.A personal perspective on high-content screening (HCS): from the beginning.Patterns of basal signaling heterogeneity can distinguish cellular populations with different drug sensitivities.Cellular heterogeneity: do differences make a difference?Extracting fluorescent reporter time courses of cell lineages from high-throughput microscopy at low temporal resolution.High-content screening data management for drug discovery in a small- to medium-size laboratory: results of a collaborative pilot study focused on user expectations as indicators of effectiveness.Concise review: a high-content screening approach to stem cell research and drug discovery.A computational platform for robotized fluorescence microscopy (I): high-content image-based cell-cycle analysis.A novel phenotypic dissimilarity method for image-based high-throughput screens.cellXpress: a fast and user-friendly software platform for profiling cellular phenotypes.Quantitative protein localization signatures reveal an association between spatial and functional divergences of proteins.Detection of cell aggregation and altered cell viability by automated label-free video microscopy: a promising alternative to endpoint viability assays in high-throughput screening.On comparing heterogeneity across biomarkers.Morphological Profiles of RNAi-Induced Gene Knockdown Are Highly Reproducible but Dominated by Seed EffectsCell Painting, a high-content image-based assay for morphological profiling using multiplexed fluorescent dyes.A metric and workflow for quality control in the analysis of heterogeneity in phenotypic profiles and screensHigh-content screening for the discovery of pharmacological compounds: advantages, challenges and potential benefits of recent technological developments.Single-cell and multivariate approaches in genetic perturbation screens.A Versatile Cell Death Screening Assay Using Dye-Stained Cells and Multivariate Image AnalysisBenchmarking of multivariate similarity measures for high-content screening fingerprints in phenotypic drug discovery.Chemoattractant concentration-dependent tuning of ERK signaling dynamics in migrating neutrophils.Automated microscopy and image analysis for androgen receptor function.Sequential array cytometry: multi-parameter imaging with a single fluorescent channel.A novel organelle map framework for high-content cell morphology analysis in high throughput.
P2860
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P2860
An approach for extensibly profiling the molecular states of cellular subpopulations.
description
2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
An approach for extensibly profiling the molecular states of cellular subpopulations.
@ast
An approach for extensibly profiling the molecular states of cellular subpopulations.
@en
type
label
An approach for extensibly profiling the molecular states of cellular subpopulations.
@ast
An approach for extensibly profiling the molecular states of cellular subpopulations.
@en
prefLabel
An approach for extensibly profiling the molecular states of cellular subpopulations.
@ast
An approach for extensibly profiling the molecular states of cellular subpopulations.
@en
P2093
P2860
P356
P1433
P1476
An approach for extensibly profiling the molecular states of cellular subpopulations.
@en
P2093
Hai-Jui Lin
Lit-Hsin Loo
Robert J Steininger
Steven J Altschuler
Yanqin Wang
P2860
P2888
P304
P356
10.1038/NMETH.1375
P577
2009-09-20T00:00:00Z
P5875
P6179
1029206549