Epitope mapping of human factor VIII inhibitor antibodies by deletion analysis of factor VIII fragments expressed in Escherichia coli.
about
Three point mutations in the factor IX genes of five hemophilia B patients. Identification strategy using localization by altered epitopes in their hemophilic proteinsDirect characterization of factor VIII in plasma: detection of a mutation altering a thrombin cleavage site (arginine-372----histidine).Inhibition of human factor VIIIa by anti-A2 subunit antibodies.Haemophilia A: effects of inhibitory antibodies on factor VIII functional interactions and approaches to prevent their action.Molecular basis of factor VIII inhibition by human antibodies. Antibodies that bind to the factor VIII light chain prevent the interaction of factor VIII with phospholipid.The concept of idiotypic vaccination against factor VIII inhibitors in haemophilia A.Pathophysiology of inhibitors to factor VIII in patients with haemophilia A.The important role of von Willebrand factor in platelet-derived FVIII gene therapy for murine hemophilia A in the presence of inhibitory antibodies.Basic aspects of inhibitors to factors VIII and IX and the influence of non-genetic risk factors.Recent developments with B-cell epitope identification for predictive studies.Complications of hemophilia A treatment: factor VIII inhibitors.Inhibition of human coagulation factor VIII by monoclonal antibodies. Mapping of functional epitopes with the use of recombinant factor VIII fragments.Use of affinity-directed liquid chromatography-mass spectrometry to map the epitopes of a factor VIII inhibitor antibody fraction.Epitope mapping of human factor IX inhibitor antibodies.Common inhibitory effects of human anti-C2 domain inhibitor alloantibodies on factor VIII binding to von Willebrand factor.Antibodies to factor VIII in plasma of patients with hemophilia A and normal subjects.Slowed release of thrombin-cleaved factor VIII from von Willebrand factor by a monoclonal and a human antibody is a novel mechanism for factor VIII inhibition.Factor VIII heavy chain polypeptides in plasma and concentrates.Analysis of the human factor VIII A2 inhibitor epitope by alanine scanning mutagenesis.Analysis of factor VIII gene inversion mutations in 166 unrelated haemophilia A families: frequency and utility in genetic counselling.Variation in factor VIII inhibitor reactivity with different commercial factor VIII preparations.Laboratory testing for factor VIII and IX inhibitors in haemophilia: A review.Molecular Characterization of the Immune Response to Factor VIII
P2860
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P2860
Epitope mapping of human factor VIII inhibitor antibodies by deletion analysis of factor VIII fragments expressed in Escherichia coli.
description
1988 nî lūn-bûn
@nan
1988 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Epitope mapping of human facto ...... expressed in Escherichia coli.
@ast
Epitope mapping of human facto ...... expressed in Escherichia coli.
@en
type
label
Epitope mapping of human facto ...... expressed in Escherichia coli.
@ast
Epitope mapping of human facto ...... expressed in Escherichia coli.
@en
prefLabel
Epitope mapping of human facto ...... expressed in Escherichia coli.
@ast
Epitope mapping of human facto ...... expressed in Escherichia coli.
@en
P2093
P2860
P356
P1476
Epitope mapping of human facto ...... expressed in Escherichia coli.
@en
P2093
DeGraaf Mahoney S
Fulcher CA
Mattingly M
Scandella D
P2860
P304
P356
10.1073/PNAS.85.16.6152
P407
P577
1988-08-01T00:00:00Z