Human factor VIII procoagulant protein. Monoclonal antibodies define precursor-product relationships and functional epitopes

Human factor VIII procoagulant protein. Monoclonal antibodies define precursor-product relationships and functional epitopes

Item
http://www.wikidata.org/entity/Q34541462
Localization of a factor VIII-inhibiting antibody epitope to a region between residues 338 and 362 of factor VIII heavy chain.Epitope mapping of human factor VIII inhibitor antibodies by deletion analysis of factor VIII fragments expressed in Escherichia coli.Direct characterization of factor VIII in plasma: detection of a mutation altering a thrombin cleavage site (arginine-372----histidine).Localization of the binding regions of a murine monoclonal anti-factor VIII antibody and a human anti-factor VIII alloantibody, both of which inhibit factor VIII procoagulant activity, to amino acid residues threonine351-serine365 of the factor VIIIMolecular basis of factor VIII inhibition by human antibodies. Antibodies that bind to the factor VIII light chain prevent the interaction of factor VIII with phospholipid.Gene therapy for hemophilia A: production of therapeutic levels of human factor VIII in vivo in mice.Factor VIII-East Hartford (arginine 1689 to cysteine) has procoagulant activity when separated from von Willebrand factor.Isolation and characterization of human factor VIII: molecular forms in commercial factor VIII concentrate, cryoprecipitate, and plasma.Localization of human factor FVIII inhibitor epitopes to two polypeptide fragments.Inhibition of human coagulation factor VIII by monoclonal antibodies. Mapping of functional epitopes with the use of recombinant factor VIII fragments.Selective factor VIII activation by the tissue factor-factor VIIa-factor Xa complex.
P2860

Human factor VIII procoagulant protein. Monoclonal antibodies define precursor-product relationships and functional epitopes

Item
http://www.wikidata.org/entity/Q34541462
description
1985 nî lūn-bûn
@nan
1985 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1985 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1985年の論文
@ja
1985年論文
@yue
1985年論文
@zh-hant
1985年論文
@zh-hk
1985年論文
@zh-mo
1985年論文
@zh-tw
1985年论文
@wuu
name
Human factor VIII procoagulant ...... nships and functional epitopes
@ast
Human factor VIII procoagulant ...... nships and functional epitopes
@en
Human factor VIII procoagulant ...... nships and functional epitopes
@nl
type
label
Human factor VIII procoagulant ...... nships and functional epitopes
@ast
Human factor VIII procoagulant ...... nships and functional epitopes
@en
Human factor VIII procoagulant ...... nships and functional epitopes
@nl
prefLabel
Human factor VIII procoagulant ...... nships and functional epitopes
@ast
Human factor VIII procoagulant ...... nships and functional epitopes
@en
Human factor VIII procoagulant ...... nships and functional epitopes
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P932
P356
P1433
P1476
Human factor VIII procoagulant ...... nships and functional epitopes
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P932