The mouse resistance protein Irgm1 (LRG-47): a regulator or an effector of pathogen defense?
about
Identification of the microsporidian Encephalitozoon cuniculi as a new target of the IFNγ-inducible IRG resistance systemHost genetics and Chlamydia disease: prediction and validation of disease severity mechanisms.The IFN-γ-inducible GTPase, Irga6, protects mice against Toxoplasma gondii but not against Plasmodium berghei and some other intracellular pathogens.Compensatory T cell responses in IRG-deficient mice prevent sustained Chlamydia trachomatis infectionsTemporal gene profiling of the 5XFAD transgenic mouse model highlights the importance of microglial activation in Alzheimer's disease.Autophagy in immunity and cell-autonomous defense against intracellular microbesLoss of the interferon-γ-inducible regulatory immunity-related GTPase (IRG), Irgm1, causes activation of effector IRG proteins on lysosomes, damaging lysosomal function and predicting the dramatic susceptibility of Irgm1-deficient mice to infection.Host interferon-γ inducible protein contributes to Brucella survival.The immunity-related GTPases in mammals: a fast-evolving cell-autonomous resistance system against intracellular pathogens.Interferon-inducible GTPases in cell autonomous and innate immunity.Irgm1 (LRG-47), a regulator of cell-autonomous immunity, does not localize to mycobacterial or listerial phagosomes in IFN-γ-induced mouse cells.Nitric Oxide Modulates Macrophage Responses to Mycobacterium tuberculosis Infection through Activation of HIF-1α and Repression of NF-κB.Irgm1 coordinately regulates autoimmunity and host defense at select mucosal surfaces.Morphine-potentiated cognitive deficits correlate to suppressed hippocampal iNOS RNA expression and an absent type 1 interferon response in LP-BM5 murine AIDS.Mechanisms of interferon-beta-induced inhibition of Toxoplasma gondii growth in murine macrophages and embryonic fibroblasts: role of immunity-related GTPase M1.
P2860
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P2860
The mouse resistance protein Irgm1 (LRG-47): a regulator or an effector of pathogen defense?
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The mouse resistance protein I ...... effector of pathogen defense?
@ast
The mouse resistance protein I ...... effector of pathogen defense?
@en
type
label
The mouse resistance protein I ...... effector of pathogen defense?
@ast
The mouse resistance protein I ...... effector of pathogen defense?
@en
prefLabel
The mouse resistance protein I ...... effector of pathogen defense?
@ast
The mouse resistance protein I ...... effector of pathogen defense?
@en
P2860
P1433
P1476
The mouse resistance protein I ...... effector of pathogen defense?
@en
P2093
Julia P Hunn
P2860
P304
P356
10.1371/JOURNAL.PPAT.1001008
P577
2010-07-15T00:00:00Z