Disruption of the Toxoplasma gondii parasitophorous vacuole by IFNgamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell death
about
A dedicated promoter drives constitutive expression of the cell-autonomous immune resistance GTPase, Irga6 (IIGP1) in mouse liverLocalisation and mislocalisation of the interferon-inducible immunity-related GTPase, Irgm1 (LRG-47) in mouse cellsGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)Autophagy in immunity and inflammationImmune response and immunopathology during toxoplasmosisMany stimuli pull the necrotic trigger, an overviewCoordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuolePhosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulenceThe activation mechanism of Irga6, an interferon-inducible GTPase contributing to mouse resistance against Toxoplasma gondiicPLA2 regulates the expression of type I interferons and intracellular immunity to Chlamydia trachomatisMaintenance of vacuole integrity by bacterial pathogensUNC93B1 mediates host resistance to infection with Toxoplasma gondiiNeurons are the Primary Target Cell for the Brain-Tropic Intracellular Parasite Toxoplasma gondiiDeterminants of GBP recruitment to Toxoplasma gondii vacuoles and the parasitic factors that control itIdentification of the microsporidian Encephalitozoon cuniculi as a new target of the IFNγ-inducible IRG resistance systemInvited review: Mechanisms of GTP hydrolysis and conformational transitions in the dynamin superfamilyPhosphorylation of mouse immunity-related GTPase (IRG) resistance proteins is an evasion strategy for virulent Toxoplasma gondiiThe CD40-autophagy pathway is needed for host protection despite IFN-Γ-dependent immunity and CD40 induces autophagy via control of P21 levelsA Toxoplasma gondii pseudokinase inhibits host IRG resistance proteinsRegulation of macrophage motility by Irgm1Dynamics of T cell, antigen-presenting cell, and pathogen interactions during recall responses in the lymph nodeCell death of gamma interferon-stimulated human fibroblasts upon Toxoplasma gondii infection induces early parasite egress and limits parasite replicationA highly conserved Toxo1 haplotype directs resistance to toxoplasmosis and its associated caspase-1 dependent killing of parasite and host macrophage.Modeling infectious disease in mice: co-adaptation and the role of host-specific IFNgamma responses.The mouse resistance protein Irgm1 (LRG-47): a regulator or an effector of pathogen defense?Strain- and Dose-Dependent Reduction of Toxoplasma gondii Burden in Pigs Is Associated with Interferon-Gamma Production by CD8+ Lymphocytes in a Heterologous Challenge Model.Processing and presentation of antigens derived from intracellular protozoan parasites.TRIM21 is critical for survival of Toxoplasma gondii infection and localises to GBP-positive parasite vacuoles.The parasitophorous vacuole membrane of Toxoplasma gondii is targeted for disruption by ubiquitin-like conjugation systems of autophagy.The IFN-γ-inducible GTPase, Irga6, protects mice against Toxoplasma gondii but not against Plasmodium berghei and some other intracellular pathogens.Subcellular antigen location influences T-cell activation during acute infection with Toxoplasma gondiiProgrammed cell death and its role in inflammationSubversion of host cellular functions by the apicomplexan parasites.The rhoptry proteins ROP18 and ROP5 mediate Toxoplasma gondii evasion of the murine, but not the human, interferon-gamma response.Hammondia hammondi, an avirulent relative of Toxoplasma gondii, has functional orthologs of known T. gondii virulence genesInterferon-γ restricts Toxoplasma gondii development in murine skeletal muscle cells via nitric oxide production and immunity-related GTPases.Temporal gene profiling of the 5XFAD transgenic mouse model highlights the importance of microglial activation in Alzheimer's disease.Autophagy in immunity and cell-autonomous defense against intracellular microbesGuanylate-binding protein 1 (Gbp1) contributes to cell-autonomous immunity against Toxoplasma gondii.Differential effects of three canonical Toxoplasma strains on gene expression in human neuroepithelial cells.
P2860
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P2860
Disruption of the Toxoplasma gondii parasitophorous vacuole by IFNgamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell death
description
2009 nî lūn-bûn
@nan
2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Disruption of the Toxoplasma g ...... ) triggers necrotic cell death
@ast
Disruption of the Toxoplasma g ...... ) triggers necrotic cell death
@en
Disruption of the Toxoplasma g ...... ) triggers necrotic cell death
@en-gb
Disruption of the Toxoplasma g ...... ) triggers necrotic cell death
@nl
type
label
Disruption of the Toxoplasma g ...... ) triggers necrotic cell death
@ast
Disruption of the Toxoplasma g ...... ) triggers necrotic cell death
@en
Disruption of the Toxoplasma g ...... ) triggers necrotic cell death
@en-gb
Disruption of the Toxoplasma g ...... ) triggers necrotic cell death
@nl
altLabel
Disruption of the Toxoplasma g ...... ) Triggers Necrotic Cell Death
@en
prefLabel
Disruption of the Toxoplasma g ...... ) triggers necrotic cell death
@ast
Disruption of the Toxoplasma g ...... ) triggers necrotic cell death
@en
Disruption of the Toxoplasma g ...... ) triggers necrotic cell death
@en-gb
Disruption of the Toxoplasma g ...... ) triggers necrotic cell death
@nl
P2093
P2860
P3181
P1433
P1476
Disruption of the Toxoplasma g ...... ) triggers necrotic cell death
@en
P2093
Aliaksandr Khaminets
Julia P Hunn
Yang O Zhao
P2860
P304
P3181
P356
10.1371/JOURNAL.PPAT.1000288
P407
P577
2009-02-01T00:00:00Z