Succinate is an inflammatory signal that induces IL-1β through HIF-1α. - Wikidata - awgldk - TriplyDB

Succinate is an inflammatory signal that induces IL-1β through HIF-1α.

Succinate is an inflammatory signal that induces IL-1β through HIF-1α.

http://www.wikidata.org/entity/Q33652731

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The rise of mitochondria in medicine Mucosal Interactions between Genetics, Diet, and Microbiome in Inflammatory Bowel Disease Metabolic Inflammation-Differential Modulation by Dietary Constituents Liver immunology and its role in inflammation and homeostasis Hypoxia-inducible factors as molecular targets for liver diseases Metabolomics in rheumatic diseases: desperately seeking biomarkers Metabolic communication in tumors: a new layer of immunoregulation for immune evasion Purinergic Signaling to Terminate TLR Responses in Macrophages Dendritic Cells under Hypoxia: How Oxygen Shortage Affects the Linkage between Innate and Adaptive Immunity Sirtuins Link Inflammation and Metabolism Histone deacetylases in monocyte/macrophage development, activation and metabolism: refining HDAC targets for inflammatory and infectious diseases Adipose tissue macrophages: going off track during obesity The Macrophage Switch in Obesity Development Immune Cells and Inflammation in Diabetic Nephropathy Immunometabolism governs dendritic cell and macrophage function Macrophages During the Fibrotic Process: M2 as Friend and Foe Molecular control of activation and priming in macrophages Exploring Internal Ribosome Entry Sites as Therapeutic Targets Control of macrophage metabolism and activation by mTOR and Akt signaling Reactive oxygen species and mitochondria: A nexus of cellular homeostasis T cell metabolism drives immunity Interplay between sirtuins, MYC and hypoxia-inducible factor in cancer-associated metabolic reprogramming Mitochondria in the regulation of innate and adaptive immunity Adipose tissue as an immunological organ Immunometabolism in Tuberculosis Fueling immunity: insights into metabolism and lymphocyte function Lung macrophages contribute to house dust mite driven airway remodeling via HIF-1α A high-fat diet and NAD(+) activate Sirt1 to rescue premature aging in cockayne syndrome TXNIP deficiency exacerbates endotoxic shock via the induction of excessive nitric oxide synthesis DAMPs, MAMPs, and NAMPs in plant innate immunity Changing perspective on oncometabolites: from metabolic signature of cancer to tumorigenic and immunosuppressive agents Regulation of Nlrp3 inflammasome by dietary metabolites Metabolic reprogramming in macrophages and dendritic cells in innate immunity Contribution of metabolic reprogramming to macrophage plasticity and function Aerobic glycolysis: beyond proliferation Initiation and perpetuation of NLRP3 inflammasome activation and assembly C13orf31 (FAMIN) is a central regulator of immunometabolic function Histone deacetylase 7 promotes Toll-like receptor 4-dependent proinflammatory gene expression in macrophages Metabolic control of dendritic cell activation and function: recent advances and clinical implications Inflammasomes and metabolic disorders: old genes in modern diseases

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P2860

Succinate is an inflammatory signal that induces IL-1β through HIF-1α.

http://www.wikidata.org/entity/Q33652731

description

2013 nî lūn-bûn

@nan

2013 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի մարտին հրատարակված գիտական հոդված

@hy

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

Succinate is an inflammatory signal that induces IL-1β through HIF-1α.

@ast

Succinate is an inflammatory signal that induces IL-1β through HIF-1α.

@en

type

label

Succinate is an inflammatory signal that induces IL-1β through HIF-1α.

@ast

Succinate is an inflammatory signal that induces IL-1β through HIF-1α.

@en

prefLabel

Succinate is an inflammatory signal that induces IL-1β through HIF-1α.

@ast

Succinate is an inflammatory signal that induces IL-1β through HIF-1α.

@en

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Succinate is an inflammatory signal that induces IL-1β through HIF-1α

@en

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A F McGettrick

http://www.w3.org/2001/XMLSchema#string

A Gardet

http://www.w3.org/2001/XMLSchema#string

B E Caffrey

http://www.w3.org/2001/XMLSchema#string

B Kelly

http://www.w3.org/2001/XMLSchema#string

C T Taylor

http://www.w3.org/2001/XMLSchema#string

E M Palsson-McDermott

http://www.w3.org/2001/XMLSchema#string

F C Beasley

http://www.w3.org/2001/XMLSchema#string

G Goel

http://www.w3.org/2001/XMLSchema#string

G M Tannahill

http://www.w3.org/2001/XMLSchema#string

H Lin

http://www.w3.org/2001/XMLSchema#string

P2860

Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase

Cell-permeating alpha-ketoglutarate derivatives alleviate pseudohypoxia in succinate dehydrogenase-deficient cells

Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma

A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase

The R22X mutation of the SDHD gene in hereditary paraganglioma abolishes the enzymatic activity of complex II in the mitochondrial respiratory chain and activates the hypoxia pathway

Characterization of a functional NF-kappa B site in the human interleukin 1 beta promoter: evidence for a positive autoregulatory loop

Circulating mitochondrial DAMPs cause inflammatory responses to injury.

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes.

Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing

P2888

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238-242

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scholarly article

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10.1038/NATURE11986

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7444

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496

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Nicholas Bernard

Christian Frezza

Sarah R Walmsley

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2013-03-24T00:00:00Z

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236087063

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23535595

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4031686

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