Endocrine profiling and prioritization of environmental chemicals using ToxCast data - Wikidata - awgldk - TriplyDB

Endocrine profiling and prioritization of environmental chemicals using ToxCast data

Endocrine profiling and prioritization of environmental chemicals using ToxCast data

http://www.wikidata.org/entity/Q33687961

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Systems biology and biomarkers of early effects for occupational exposure limit setting Diverse convergent evidence in the genetic analysis of complex disease: coordinating omic, informatic, and experimental evidence to better identify and validate risk factors Big data in chemical toxicity research: the use of high-throughput screening assays to identify potential toxicants Chemical Safety Assessment Using Read-Across: Assessing the Use of Novel Testing Methods to Strengthen the Evidence Base for Decision Making Evidence that bisphenol A (BPA) can be accurately measured without contamination in human serum and urine, and that BPA causes numerous hazards from multiple routes of exposure Addressing human variability in next-generation human health risk assessments of environmental chemicals A model for aryl hydrocarbon receptor-activated gene expression shows potency and efficacy changes and predicts squelching due to competition for transcription co-activators Toxicity testing in the 21 century: defining new risk assessment approaches based on perturbation of intracellular toxicity pathways Structural and Functional Elucidation of Yeast Lanosterol 14α-Demethylase in Complex with Agrochemical Antifungals Predictive modeling of chemical hazard by integrating numerical descriptors of chemical structures and short-term toxicity assay data Editor's Highlight: Screening ToxCast Prioritized Chemicals for PPARG Function in a Human Adipose-Derived Stem Cell Model of Adipogenesis Editor's Highlight: Development of an In vitro Assay Measuring Uterine-Specific Estrogenic Responses for Use in Chemical Safety Assessment Supporting read-across using biological data High-performance metabolic profiling of plasma from seven mammalian species for simultaneous environmental chemical surveillance and bioeffect monitoring.ToxPi GUI: an interactive visualization tool for transparent integration of data from diverse sources of evidence.Developing predictive approaches to characterize adaptive responses of the reproductive endocrine axis to aromatase inhibition: I. Data generation in a small fish model.Incorporating new technologies into toxicity testing and risk assessment: moving from 21st century vision to a data-driven framework.Non-monotonic dose responses in studies of endocrine disrupting chemicals: bisphenol a as a case study Mapping the human toxome by systems toxicology.A round robin approach to the analysis of bisphenol A (BPA) in human blood samples.Chemical genomics profiling of environmental chemical modulation of human nuclear receptors.What Are We Putting in Our Food That Is Making Us Fat? Food Additives, Contaminants, and Other Putative Contributors to Obesity.Environmental impact on vascular development predicted by high-throughput screening.A framework for the next generation of risk science.A three-stage algorithm to make toxicologically relevant activity calls from quantitative high throughput screening data Test driving ToxCast: endocrine profiling for 1858 chemicals included in phase II.Integrated Model of Chemical Perturbations of a Biological Pathway Using 18 In Vitro High-Throughput Screening Assays for the Estrogen Receptor.Quantitative high-throughput screening for chemical toxicity in a population-based in vitro model Tiered High-Throughput Screening Approach to Identify Thyroperoxidase Inhibitors Within the ToxCast Phase I and II Chemical Libraries.Biosensor zebrafish provide new insights into potential health effects of environmental estrogens Bisphenol A sulfonation is impaired in metabolic and liver disease Using in vitro high throughput screening assays to identify potential endocrine-disrupting chemicals.Improving the human hazard characterization of chemicals: a Tox21 update On the Utility of ToxCast™ and ToxPi as Methods for Identifying New Obesogens.Regulatory decisions on endocrine disrupting chemicals should be based on the principles of endocrinology.Reply to "Comment on 'On the Utility of ToxCast™ and ToxPi as Methods for Identifying New Obesogens'".Disruption of embryonic vascular development in predictive toxicology.Developmental neurotoxicity testing: a path forward.Alternatives to in vivo tests to detect endocrine disrupting chemicals (EDCs) in fish and amphibians--screening for estrogen, androgen and thyroid hormone disruption.In vitro and modelling approaches to risk assessment from the U.S. Environmental Protection Agency ToxCast programme.

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Endocrine profiling and prioritization of environmental chemicals using ToxCast data

http://www.wikidata.org/entity/Q33687961

description

2010 nî lūn-bûn

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2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Endocrine profiling and prioritization of environmental chemicals using ToxCast data

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Endocrine profiling and prioritization of environmental chemicals using ToxCast data

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type

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Endocrine profiling and prioritization of environmental chemicals using ToxCast data

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Endocrine profiling and prioritization of environmental chemicals using ToxCast data

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Endocrine profiling and prioritization of environmental chemicals using ToxCast data

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Endocrine profiling and prioritization of environmental chemicals using ToxCast data

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Environmental Health Perspectives

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Endocrine profiling and prioritization of environmental chemicals using ToxCast data

@en

P2093

Ann M Richard

http://www.w3.org/2001/XMLSchema#string

David J Dix

http://www.w3.org/2001/XMLSchema#string

Keith A Houck

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Robert J Kavlock

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Shirlee W Tan

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Thomas B Knudsen

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NTP-CERHR expert panel report on the reproductive and developmental toxicity of bisphenol A

KEGG: Kyoto Encyclopedia of Genes and Genomes

Correlation between thyroid hormone status and hepatic hyperplasia and hypertrophy caused by the peroxisome proliferator-activated receptor alpha agonist Wy-14,643

Endocrine-disrupting potential of bisphenol A, bisphenol A dimethacrylate, 4-n-nonylphenol, and 4-n-octylphenol in vitro: new data and a brief review.

Cellular and molecular mechanisms of action of linuron: an antiandrogenic herbicide that produces reproductive malformations in male rats.

Homogeneous reporter system enables quantitative functional assessment of multiple transcription factors.

Impact of environmental chemicals on key transcription regulators and correlation to toxicity end points within EPA's ToxCast program.

In vitro screening of environmental chemicals for targeted testing prioritization: the ToxCast project

Regulation of constitutive androstane receptor and its target genes by fasting, cAMP, hepatocyte nuclear factor alpha, and the coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha

The ToxCast program for prioritizing toxicity testing of environmental chemicals.

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1714-1720

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scholarly article

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10.1289/EHP.1002180

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12

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118

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Matthew T Martin

Richard S. Judson

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2010-09-08T00:00:00Z

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46180858

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20826373

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3002190

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