Regulation of constitutive androstane receptor and its target genes by fasting, cAMP, hepatocyte nuclear factor alpha, and the coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha
about
Regulation of the cytosolic sulfotransferases by nuclear receptorsCrosstalk of HNF4α with extracellular and intracellular signaling pathways in the regulation of hepatic metabolism of drugs and lipidsFasting-Induced Changes in Hepatic P450 Mediated Drug Metabolism Are Largely Independent of the Constitutive Androstane Receptor CARExercise and adrenaline increase PGC-1{alpha} mRNA expression in rat adipose tissueGene expression profiling reveals a regulatory role for ROR alpha and ROR gamma in phase I and phase II metabolismFasting induces basolateral uptake transporters of the SLC family in the liver via HNF4alpha and PGC1alpha.Sexually dimorphic regulation and induction of P450s by the constitutive androstane receptor (CAR).The transcriptional regulation of the human CYP2C genesEndocrine profiling and prioritization of environmental chemicals using ToxCast dataHepatocyte nuclear factor 4{alpha} regulates rifampicin-mediated induction of CYP2C genes in primary cultures of human hepatocytesFibroblast growth factor (Fgf) 21 is a novel target gene of the aryl hydrocarbon receptor (AhR).Activation of CAR and PXR by Dietary, Environmental and Occupational Chemicals Alters Drug Metabolism, Intermediary Metabolism, and Cell Proliferation.Knockdown of SF-1 and RNF31 affects components of steroidogenesis, TGFβ, and Wnt/β-catenin signaling in adrenocortical carcinoma cells.HNF4α--role in drug metabolism and potential drug target?Pregnane X receptor and constitutive androstane receptor at the crossroads of drug metabolism and energy metabolism.CYP2B6: new insights into a historically overlooked cytochrome P450 isozymeNCOA6 differentially regulates the expression of the CYP2C9 and CYP3A4 genesCINPA1 is an inhibitor of constitutive androstane receptor that does not activate pregnane X receptor.UDP-glucuronosyltransferase expression in mouse liver is increased in obesity- and fasting-induced steatosisSmall-molecule modulators of the constitutive androstane receptor.Transcriptional Regulation of CYP2B6 Expression by Hepatocyte Nuclear Factor 3β in Human Liver Cells.Deciphering the roles of the constitutive androstane receptor in energy metabolism.Neonatal activation of the nuclear receptor CAR results in epigenetic memory and permanent change of drug metabolism in mouse liverCAR Suppresses Hepatic Gluconeogenesis by Facilitating the Ubiquitination and Degradation of PGC1α.The transcriptional activity of hepatocyte nuclear factor 4 alpha is inhibited via phosphorylation by ERK1/2.Nuclear receptor CAR requires early growth response 1 to activate the human cytochrome P450 2B6 geneEffects of adult onset mild calorie restriction on weight of reproductive organs, plasma parameters and gene expression in male mice.p38 Mitogen-activated protein kinase regulates nuclear receptor CAR that activates the CYP2B6 geneXenobiotic-sensing nuclear receptors involved in drug metabolism: a structural perspectiveCell signaling and nuclear receptors: new opportunities for molecular pharmaceuticals in liver disease.Nuclear receptors as therapeutic targets in cholestatic liver diseases.A concentration addition model for the activation of the constitutive androstane receptor by xenobiotic mixtures.Bile Acid sulfation: a pathway of bile acid elimination and detoxification.The constitutive androstane receptor is an anti-obesity nuclear receptor that improves insulin sensitivity.Fasting induces nuclear factor E2-related factor 2 and ATP-binding Cassette transporters via protein kinase A and Sirtuin-1 in mouse and humanNuclear receptors: the controlling force in drug metabolism of the liver?Sterol regulation of metabolism, homeostasis, and development.Signaling control of the constitutive androstane receptor (CAR)Nuclear receptor-mediated regulation of carboxylesterase expression and activity.Role of the constitutive androstane receptor in obesity and type 2 diabetes: a case study of the endobiotic function of a xenobiotic receptor.
P2860
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P2860
Regulation of constitutive androstane receptor and its target genes by fasting, cAMP, hepatocyte nuclear factor alpha, and the coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha
description
2006 nî lūn-bûn
@nan
2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Regulation of constitutive and ...... eptor gamma coactivator-1alpha
@ast
Regulation of constitutive and ...... eptor gamma coactivator-1alpha
@en
Regulation of constitutive and ...... eptor gamma coactivator-1alpha
@nl
type
label
Regulation of constitutive and ...... eptor gamma coactivator-1alpha
@ast
Regulation of constitutive and ...... eptor gamma coactivator-1alpha
@en
Regulation of constitutive and ...... eptor gamma coactivator-1alpha
@nl
prefLabel
Regulation of constitutive and ...... eptor gamma coactivator-1alpha
@ast
Regulation of constitutive and ...... eptor gamma coactivator-1alpha
@en
Regulation of constitutive and ...... eptor gamma coactivator-1alpha
@nl
P2093
P2860
P356
P1476
Regulation of constitutive and ...... eptor gamma coactivator-1alpha
@en
P2093
Frank J Gonzalez
Insook Kim
Jeff L Staudinger
Kristin Lichti
Xunshan Ding
P2860
P304
26540-26551
P356
10.1074/JBC.M600931200
P407
P577
2006-07-05T00:00:00Z