Evidence for both the nucleus and cytoplasm as subcellular sites of pathogenesis in Huntington's disease in cell culture and in transgenic mice expressing mutant huntingtin.
about
dAtaxin-2 mediates expanded Ataxin-1-induced neurodegeneration in a Drosophila model of SCA1Intrabody gene therapy ameliorates motor, cognitive, and neuropathological symptoms in multiple mouse models of Huntington's disease.Caspase 3-cleaved N-terminal fragments of wild-type and mutant huntingtin are present in normal and Huntington's disease brains, associate with membranes, and undergo calpain-dependent proteolysis.Modification of brain aging and neurodegenerative disorders by genes, diet, and behavior.Molecular pathogenesis of spinocerebellar ataxia type 6.An in vitro perspective on the molecular mechanisms underlying mutant huntingtin protein toxicityStudying neurodegenerative diseases in culture models.Association of polyalanine and polyglutamine coiled coils mediates expansion disease-related protein aggregation and dysfunctionYorkie Regulates Neurodegeneration Through Canonical Pathway and Innate Immune Response.
P2860
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P2860
Evidence for both the nucleus and cytoplasm as subcellular sites of pathogenesis in Huntington's disease in cell culture and in transgenic mice expressing mutant huntingtin.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Evidence for both the nucleus ...... expressing mutant huntingtin.
@ast
Evidence for both the nucleus ...... expressing mutant huntingtin.
@en
type
label
Evidence for both the nucleus ...... expressing mutant huntingtin.
@ast
Evidence for both the nucleus ...... expressing mutant huntingtin.
@en
prefLabel
Evidence for both the nucleus ...... expressing mutant huntingtin.
@ast
Evidence for both the nucleus ...... expressing mutant huntingtin.
@en
P2093
P2860
P356
P1476
Evidence for both the nucleus ...... e expressing mutant huntingtin
@en
P2093
P2860
P304
P356
10.1098/RSTB.1999.0457
P407
P577
1999-06-01T00:00:00Z